Dabigatran

Pradaxa

Pradaxa, also known as Dabigatran, has been approved by the FDA as a prescription drug. It is used to treat deep vein thrombosis and pulmonary embolism in adults after they have received 5 to 10 days of injectable anticoagulants. Dabigatran, its active component, belongs to a class of drugs known as direct thrombin inhibitors. Pradaxa is available in capsule form and is taken by mouth. If you want to buy Pradaxa Online, you need to have a valid prescription from your doctor.

Product Overview

Pradaxa, or Dabigatran, is an FDA-approved medicine that prevents blood clots. It’s prescribed to people from as young as 3 months to adults, especially useful for those with a type of heart rhythm disorder called atrial fibrillation, as it reduces the risk of strokes and clots. Available in capsules of 75 mg, 110 mg, and 150 mg, the dosage depends on the patient’s age, weight, and health conditions. 

For example, adults with atrial fibrillation typically take 75-150 mg two times per day. After hip surgery, the dose starts at 110 mg, then 220 mg daily for about a month. Dosages for children are set by their doctors based on weight. Side effects can include easy bruising, stomach pain, mild bleeding, and heartburn. 

It’s important to follow your doctor’s instructions and discuss all other medications you’re taking to avoid interactions. So, if you want to buy Pradaxa online from Canada, please consult with your healthcare provider.

Uses of Pradaxa

• Pradaxa is used to treat children aged 3 months to under 18 years with blood clots, following at least 5 days of prior treatment with another blood thinner.
• It helps prevent the recurrence of blood clots in both adults and children after previous treatments.
• Pradaxa is also prescribed after hip replacement surgery to prevent DVT (deep vein thrombosis) or pulmonary embolism (PE).
• In adults with non-valvular atrial fibrillation, a type of heart rhythm disorder, Pradaxa reduces the risk of stroke and blood clots.

Benefits of Pradaxa

• Does not require routine blood tests.
• Fewer dietary restrictions compared to warfarin.
• Simplified dosing compared to other anticoagulants.

Side Effects of Pradaxa

Common Pradaxa side effects may include:

• Nausea
• Esophagus Mild Bleeding
• Mild Bleeding
• Gastroesophageal Reflux Disease (GERD)
• Heartburn
• Bruising More Easily
• Upper Abdominal Pain

[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]

Pradaxa Dosage

Forms & Strengths

Pradaxa capsules can be taken orally and available in the following strengths:

• Pradaxa 75 mg capsules
• Pradaxa 110 mg capsules
• Pradaxa 150 mg capsules

Recommended Dosage for Different Patients

Preventing Stroke & Patients with Blood Clots in Nonvalvular Atrial Fibrillation

• Adults: 75-150 mg two times per day.
• Children: Follow your doctor’s instructions.

Preventing Blood Clots After Hip Replacement Surgery

• Adults: Take 110 mg 1-4 hours post-surgery, then 220 mg daily for 28-35 days.
• Children: Follow your doctor’s instructions.

Treatment and Prevention of Blood Clots

• Adults: 150 mg two times per day.
• Children (8 years and older): Dosage varies by weight; follow your doctor’s instructions.

Weight-based Dosage for Children

• Over 81 kg: 260 mg two times per day.
• 61-80 kg: 220 mg two times per day.
• 41-60 kg: 185 mg two times per day.
• 26-40 kg: 150 mg two times per day.
• 16-25 kg: 110 mg two times per day.
• 11-15 kg: 75 mg two times per day.

For Pellets: Treatment and Prevention of Blood Clots

• Children (2-12 years): Dosage based on weight; follow your doctor’s instructions.

Weight-based Dosage for Children

• Over 41 kg: 260 mg two times per day.
• 21-40 kg: 220 mg two times per day.
• 16-20 kg: 170 mg two times per day.
• 13-15 kg: 140 mg two times per day.
• 11-12 kg: 110 mg two times per day.
• 9-11 kg: 90 mg two times per day.
• 7-9 kg: 70 mg two times per day.

Specific Dosages by Age and Weight

• 18-24 months, 21-25 kg: 180 mg two times per day.
• 12-24 months, 16-20 kg: 140 mg two times per day.
• 11-24 months, 13-15 kg: 140 mg two times per day.
• 10-11 months, 11-13 kg: 100 mg two times per day.
• 18-24 months, 11-12 kg: 110 mg two times per day.
• 8-18 months, 9-11 kg: 100 mg two times per day.
• 11-24 months, 9-11 kg: 90 mg two times per day.
• 6-11 months, 8-11 kg: 80 mg two times per day.
• 5-6 months, 7-9 kg: 60 mg two times per day.
• 9-24 months, 7-9 kg: 70 mg two times per day.
• 4-9 months, 7-9 kg: 60 mg two times per day.
• 3-4 months, 5-7 kg: 50 mg two times per day.
• 5-24 months, 5-7 kg: 50 mg two times per day.
• 3-5 months, 3-4 kg: 40 mg two times per day.
• 3-6 months, 3-4 kg: 30 mg two times per day.
• 3-10 months, 4-5 kg: 40 mg two times per day.

How to Take Pradaxa?

• Follow the dosage and schedule prescribed by your healthcare provider for Pradaxa Capsules.
• Swallow capsules whole with a full glass of water; do not break, chew, or empty the pellets.
• Take Pradaxa Capsules with or without food as instructed.
• Always take Pradaxa Capsules with a full glass of water to aid absorption.

Missed Dose 

If you miss a dose of Pradaxa, you should take it as soon as you remember unless it’s close to the time for your next dose. If less than six hours remain before your next dose, skip the missed dose of Pradaxa and continue with your regular dosing schedule. In the case of missing part of an oral pellet dose, wait at least 12 hours before taking the next dose; do not take another dose immediately.

[Note: Do not take two doses of Pradaxa at the same time to compensate for a missed dose. This can increase your chance of experiencing various side effects.]

Overdose

If you take more Pradaxa than prescribed, you risk excessive bleeding. In the event of a suspected overdose of Pradaxa, it is crucial to seek immediate medical help. Call 911 or go to the nearest emergency room without delay.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Pradaxa Work?

Pradaxa functions by binding to thrombin, a crucial component in blood clot formation. By inhibiting thrombin’s clotting capabilities, Pradaxa effectively slows down the clot formation process. Therefore, using Pradaxa helps prevent the formation of blood clots within the blood vessels.

Important Safety Precautions

• Do not take Pradaxa if you are allergic to its ingredients. 
• Discuss your medical history with your doctor or healthcare provider, particularly if you have:
  • A genetic spinal defect
  • A catheter in your spine for administering medication
  • Past spine problems or spinal surgery
  • History of difficult or repeated spinal taps
  • Bleeding disorders
  • A stomach ulcer or gastrointestinal bleeding
  • Use of medications that increase bleeding risk
  • Antiphospholipid syndrome, which heightens blood clot risks
  • Plans for upcoming surgery, medical or dental procedures, or kidney disease

• Inform your doctor if you are pregnant or plan to become pregnant, as Pradaxa may cause bleeding in both mother and baby. Do not breastfeed while taking Pradaxa.

Storage 

• Store Pradaxa at room temperature between 68° F & 77° F (20° C to 25° C).
• Use capsules within 4 months of opening the bottle; dispose of any unused capsules after this period.
• Keep the capsules in their original bottle or blister pack to protect against moisture.
• Do not use pill boxes or organizers to store Pradaxa.
• Keep Pradaxa and all medications out of reach of children and pets.
• Regularly check the expiration date and discard expired medication.

Pradaxa Interactions

• Apixaban
• Aspirin
• Heparin
• Clopidogrel
• Rivaroxaban
• Enoxaparin
• Dronedarone
• Ketoconazole
• Ibuprofen
• Prasugrel
• Naproxen
• Warfarin
• Dalteparin
• Defibrotide
• Rifampin

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

Pradaxa Alternatives

• Dabigatran (dabigatran etexilate)
• Xarelto (rivaroxaban)
• Eliquis (apixaban)
• Apixaban (apixaban)
• Rivaroxaban (rivaroxaban)
• Coumadin (warfarin sodium)
• Warfarin (warfarin sodium)
• Plavix (clopidogrel)

[Note: Your healthcare provider will choose which Pradaxa alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

How is Pradaxa different from warfarin?

Warfarin, though a longstanding and effective medication, requires careful dietary monitoring and regular blood tests. In contrast, newer medications like Pradaxa and Xarelto demand less patient oversight but still carry risks of bleeding.

What is the age limit for Pradaxa?

Pradaxa is safe and effective for pediatric patients aged 8 to less than 18 years, specifically for the treatment & prevention of recurrent venous thromboembolism.

How long should I take Pradaxa?

The duration for which dabigatran is prescribed depends on the condition being treated:

• For a knee joint replacement, dabigatran is typically taken for 10 days.
• For a hip joint replacement, the usual course is 4 to 5 weeks.
• For a blood clot, the treatment period with dabigatran generally lasts at least 3 months, depending on the underlying cause of the clot.

What happens if I stop taking Pradaxa?

It is crucial to understand that stopping Pradaxa can significantly increase your risk of stroke or developing blood clots. 

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