Buy Novolin GE 50/50 Penfill Cartridge Online from Canada
Novolin GE 50/50
Novolin GE 50/50 is a premixed insulin therapy designed for managing diabetes mellitus, blending fast and intermediate-acting insulins to stabilize blood sugar levels. It’s available in 100 units/ml injectable suspensions for subcutaneous administration, tailored for adults and pediatric patients. Dosage varies by individual needs, emphasizing the importance of following medical guidance to avoid complications like hypoglycemia. Proper storage and handling, including not sharing needles or pens, are crucial for safety. This medication facilitates effective glycemic control, requiring careful adherence to prescribed regimens under healthcare supervision.
Product Overview
Novolin GE 50/50 is a premixed insulin therapy combining fast-acting and intermediate-acting insulin, specifically designed to control blood sugar levels in individuals with diabetes mellitus. This formulation aims to facilitate glycemic management by offering a balanced approach to insulin replacement. The active ingredients work synergistically to improve blood glucose absorption and storage, reducing the risks associated with uncontrolled blood sugar levels.
Available in injectable suspension forms of 100 units/ml in 3 ml and 10 ml vials, Novolin GE 50/50 is administered subcutaneously, offering flexibility in dosing tailored to the patient’s needs. It is suitable for adults and pediatric patients, with dosing guidelines recommending a daily maintenance dosage that varies based on body weight and diabetic condition type. Its dosing regimen mimics the body’s natural insulin release, providing a stable blood sugar level throughout the day.
While Novolin GE 50/50 effectively manages diabetes, it requires careful handling. Patients must adhere to prescribed dosages to avoid complications such as hypoglycemia, allergic reactions, or potassium imbalances. It is essential to store the medication correctly, avoid exposure to extreme temperatures, and never share insulin pens or needles to prevent contamination.
Uses of Novolin GE 50/50
- Used to improve glycemic control in adults and pediatric patients with diabetic mellitus.
How to Use Novolin GE 50/50?
Dosage
Strengths and Forms
Injectable Suspension
- 100 units/ml (3ml)
- 100 units/ml (10ml)
Recommended Dosage for Different Patients
Type 1 Diabetes Mellitus
- The typical daily maintenance dosage ranges from 0.5 to 1 unit/kg/day, administered subcutaneously in divided doses.
- Non-obese people may need 0.4 to 0.6 units/kg/day, and obese people require 0.8 to 1.2 units/kg/day.
Type 2 Diabetes Mellitus
Initial dose recommendation: 0.2 units/kg/day.
Morning Dosing:
- Administer two-thirds of the daily insulin dose subcutaneously (SC).
- Use a ratio of regular insulin to NPH insulin of 1:2.
Evening Dosing:
- Administer one-third of the daily insulin dose subcutaneously (SC).
- Use a ratio of regular insulin to NPH insulin of 1:1.
Blood Sugar Patterns (over 3 days):
- Identify consistent patterns in blood sugar levels for more than 3 days.
- Compare blood glucose levels at the same time each day.
- Calculate the blood glucose range for each time of day.
- Determine the median blood glucose level.
- Consider eating and activity patterns throughout the day.
Blood Glucose Adjustments:
- Adjust only one insulin dose at a time.
- Address hypoglycemia first.
- Next, correct the highest blood sugar levels.
- If all blood sugars are high (within 2.75 mmol/L [50 mg/dL]), start by correcting the morning fasting blood glucose.
- Change insulin doses in small increments: 1-2 units for type 1 diabetes, and 2-3 for type 2 diabetes.
Sliding Scales:
- Various sliding scales exist to determine the exact insulin dose based on frequent blood glucose monitoring.
- Scales are commonly written for blood glucose tests every 4 hours (q4hr).
- Sliding scale coverage usually starts when blood glucose exceeds 11 mmol/L (200 mg/dL).
- If coverage is needed every 4 hours for 24 hours, adjust the base insulin dose first; sliding scale doses may be increased as required.
[Note: Remember these recommendations may vary depending on person to person. Discuss it with your doctor, and they’ll change your dosage accordingly.]
How to Take It?
Step 1: Check that you have the correct type of insulin, mainly if you use different types.
Step 2: Inspect the vial and insulin. It should be cloudy or milky. Don’t use it if the cap is missing, the contents look lumpy, or if it has solid particles.
Step 3: Wash your hands with soap and water.
Step 4: If using a new vial, remove the cap and clean the rubber stopper with an alcohol swab.
Step 5: Gently roll the vial 10 times to mix the insulin. Avoid shaking it.
Step 6: Draw the correct insulin dose into the syringe, checking for air bubbles. If there are bubbles, tap the syringe and adjust the dose.
Step 7: Inject the insulin under the skin of your stomach area, buttocks, thighs, or upper arms. Rotate your injection sites to avoid skin problems.
Step 8: Do not inject into areas with pits, lumps, tenderness, bruises, scaliness, hardness, or damaged skin.
Step 9: After injecting, do not recap the needle. Dispose of used syringes and needles in a puncture-resistant container.
[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]
How Does Novolin GE 50/50 Work?
Novolin GE 50 is a premixed insulin formulation consisting of a combination of rapid-acting insulin (insulin regular) and intermediate-acting insulin (insulin NPH). The rapid-acting insulin begins to take effect approximately 30 minutes after injection. Intermediate-acting insulin aids in absorbing and storing sugar and fat from your bloodstream following a meal.
Important Safety Information
Side Effects
Common Side Effects
- Hypoglycemia
- Injection site reactions
- Allergic responses
- Subcutaneous fat accumulation
- Increased body weight
- Edema
- Lipohypertrophy
Adverse/Serious Side Effects
- Severe hypoglycemia (extremely low blood sugar): Untreated, it can result in unconsciousness, seizures, and potentially death.
- Severe allergic reactions: Symptoms include rash, hives, facial swelling, tongue swelling, throat swelling, and breathing difficulties.
- Dangerously low potassium levels: Without treatment, this can cause breathing difficulties, irregular heartbeat, and potentially death.
[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]
Warnings
Hypoglycemia: Low blood sugar levels are a common side effect of insulin, including Novolin GE 50/50. Untreated low or high blood sugar can lead to loss of consciousness, coma, or death.
Allergic Reactions: Some individuals may experience severe allergic reactions, such as widespread rash or blisters, seizures, swelling of the face or throat, difficulty breathing, wheezing, or an itchy skin rash, leading to unconsciousness.
Glucose Monitoring: It is recommended that all individuals with diabetes regularly check their blood sugar levels.
Medical Supervision: Any changes in insulin should be made carefully and only with the guidance of a healthcare professional.
Precautions
Allergy: Ensure you are not allergic to any of the ingredients in Novolin GE 50/50.
Dosage: Follow your healthcare provider’s instructions regarding dosage and timing. Do not adjust your dose without consulting your doctor.
Blood Sugar Monitoring: Regularly monitor your blood sugar levels as directed by your healthcare provider.
Hypoglycemia: Be aware of the signs of low blood sugar (hypoglycemia) and carry a quick source of sugar with you in case you need it.
Injection Site: Rotate injection sites to prevent skin issues such as lipodystrophy.
Expiration: Do not use the insulin past its expiration date.
Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
Medical Conditions: Inform your doctor of any other medical conditions you have, especially kidney or liver problems, as these may affect how your body uses insulin.
Alcohol: Be cautious with alcohol consumption, as it can affect blood sugar levels.
Other Medications: Inform your healthcare provider of all other medications you are taking, as they may interact with insulin.
Novolin GE 50/50 Contraindications
Contraindications refer to specific medical conditions or circumstances where a medication should not be used due to safety risks. If you have any of the following conditions or if any of the following situations apply to you, inform your healthcare provider as Novolin may not be safe for you: Experiencing episodes of low blood sugar (hypoglycemia)
Missed Dose
Take the medication as soon as you remember, but skip the missed dose if it’s almost time for your next dose. Avoid taking two doses at once. Ensure that you refill your prescription before completely running out of the medication.
[Note: If you have missed a medication dose and are still determining when to take the next one, immediately consult your doctor or pharmacist.]
Overdose
An overdose of insulin can lead to dangerously low blood sugar levels, which can be life-threatening. Symptoms may include feeling sleepy, confused, having blurry vision, numbness or tingling in your mouth, difficulty speaking, muscle weakness, uncoordinated or jerky movements, seizures, or passing out.
[Note: If you have over-consumed the medication, get medical help immediately or contact the Poison Help line at 1-800-222-1222.]
Storage
Unopened Vials or Pens: Store unopened vials or pens in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). Do not freeze. If Novolin GE 50/50 freezes, discard it.
Opened Vials: Once opened, vials can be stored in the refrigerator or at room temperature below 30°C (86°F). Use within 28 days and discard after this period.
Opened Pens: Once in use, pens should be kept at room temperature, below 30°C (86°F), and should not be refrigerated. Use within 28 days and discard after this period.
Protection from Light: Keep the vials and pens away from direct light.
Do Not Shake: Avoid shaking the insulin as it may affect its effectiveness.
Do Not Use If: Do not use Novolin GE 50/50 if it appears cloudy, thickened, or has particles after mixing.
[Note: Discuss with your healthcare professional about the proper disposal of any unused medicine and any questions you may have regarding its storage.]
Novolin GE 50/50 Interactions
- Sulfonylureas
- Meglitinides
- Beta-Blockers
- Thiazolidinediones (TZDs)
- Corticosteroids
- Sympathomimetic Agents
- ACE Inhibitors
- ARBs (Angiotensin Receptor Blockers)
- Certain Antibiotics
- Certain Antipsychotics
[Note: This isn’t a complete list, and there could be other drugs that interact with Novolin GE 50/50. Make sure to tell your doctor any prescription, over-the-counter medicines, and herbal products you’re taking.]
Novolin GE 50/50 Alternatives
- Novolog (insulin aspart)
- Apidra (insulin glulisine)
- Humalog KwikPen (insulin lispro)
- Humulin R (insulin regular)
- Humulin N (insulin isophane)
- Levemir (insulin detemir)
- Tresiba FlexTouch (insulin degludec)
- Basaglar KwikPen (insulin glargine)
- Humulin 70/30 (insulin isophane)
[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.]
Frequently Asked Questions
Is it safe to adjust the dosage of Novolin on my own?
No, it is unsafe to adjust the dosage of Novolin on your own. Any changes in dosage should be discussed and approved by your healthcare provider. They will consider your specific medical condition, blood sugar levels, and other factors to make appropriate adjustments for safe and effective diabetes management.
How long does a Novolin Penfill Cartridge last once opened?
Once opened, a Novolin Penfill Cartridge typically lasts for up to 28 days if stored at room temperature (between 59°F to 86°F or 15°C to 30°C). It’s important to discard the cartridge after this period to ensure the medication’s effectiveness and safety.
What should I do if I experience a hypoglycemic episode while using Novolin?
If you experience a hypoglycemic episode while using Novolin, consume a fast-acting source of glucose like juice, candy, or glucose gel. Check your blood sugar after 15 minutes and repeat if necessary. Rest, monitor your levels, and eat a balanced meal. If symptoms persist or worsen, seek medical attention promptly.
How frequently should I monitor my blood sugar levels on Novolin?
While using Novolin, monitor your blood sugar levels regularly. The frequency may vary depending on your healthcare provider’s recommendations and your individual needs. Typically, it’s advised to check before meals, before bedtime, and occasionally during the night. Additionally, monitor if you experience symptoms of high or low blood sugar. Always follow your healthcare provider’s specific guidance.
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