Buy Myrbetriq Tablets Online from Canada To Treat Overactive Bladder
Mirabegron
Buy Myrbetriq Online from Canada
Myrbetriq effectively treats the Overactive Bladder (OAB) and Neurogenic Detrusor Overactivity (NDO) by relaxing the bladder muscle, increasing capacity, and reducing urinary frequency and urgency. Available in 25 mg and 50 mg tablets, it’s suitable for adults and requires careful dosing adjustments for special populations. Side effects are manageable, and they interact with various drugs. Always consult healthcare providers for personalized advice and monitoring.
Product Overview
Myrbetriq (mirabegron) is used primarily to manage symptoms of Overactive Bladder (OAB) and Neurogenic Detrusor Overactivity (NDO). It effectively reduces urinary frequency, decreases urination urgency, and improves bladder control by relaxing the bladder muscle, thereby increasing its capacity. This results in fewer episodes of incontinence and significantly elevates the quality of life for patients. Myrbetriq is available in tablet and extended-release forms, with standard dosages of 25 mg and 50 mg.
Myrbetriq’s side effects are generally manageable, including increased blood pressure, urinary tract infections, headache, and dizziness. For specific patient groups such as the older adults, those with renal or hepatic impairment, and pediatric cases, dosage adjustments and cautious use are advised to maximize safety and efficacy. Regular blood pressure monitoring and adherence to dosage guidelines are crucial for optimal treatment outcomes.
Myrbetriq interacts with various drugs like CYP2D6 substrates and antihypertensives, potentially impacting their effectiveness or necessitating dosage adjustments. It should be stored at an average room temperature, in a dry place, and away from direct light to maintain its efficacy. Patients should consult their healthcare provider to understand potential interactions with other medications. Alternatives to Myrbetriq include medications such as oxybutynin and solifenacin, offering options for patients who may respond differently to various treatments.
Uses of Myrbetriq
- Overactive Bladder (OAB)
- Neurogenic Detrusor Overactivity (NDO)
- Urinary Retention
Benefits of Myrbetriq
- Reduces urinary frequency
- Decreases urgency to urinate
- Improves bladder control
- Increases bladder capacity
- Reduces incontinence episodes
- Improves quality of life for overactive bladder patients
- It can be effective for those who don’t respond to anticholinergics
Side Effects of Myrbetriq
Common side effects of Myrbetriqmay include:
- Increased blood pressure
- Urinary tract infection (UTI)
- Headache
- Nausea
- Diarrhea
- Constipation
- Dizziness
- Back pain
- Dry mouth
- Fatigue
- Abdominal pain
- Influenza-like symptoms
[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Myrbetriq Dosage
Forms & Strengths
Myrbetriq comes in tablet and extended-release forms, and the following dosage strengths:
- 25mg
- 50mg
Recommended Dosages
Overactive Bladder (OAB) in Adults:
- Starting Dose: 25 mg orally once daily.
- Combination Therapy: Can be taken with 5 mg of solifenacin (Vesicare).
- Potential Increase: May increase to 50 mg once daily after 1 to 2 months based on the provider’s evaluation.
Neurogenic Detrusor Overactivity (NDO) in Children:
- Children ≤ 77 pounds (35 kg) with Myrbetriq Granules:
- Dose Range: 24 mg to 64 mg orally once daily, adjusted based on body weight.
- Children > 77 pounds (35 kg):
- Myrbetriq Tablets:
- Starting Dose: 25 mg orally once daily.
- Potential Increase: Increase to 50 mg once daily after 1 to 2 months.
- Myrbetriq Granules:
- Starting Dose: 48 mg orally once daily.
- Potential Increase: May increase to 80 mg once daily after 1 to 2 months.
- Myrbetriq Tablets:
Elderly Patients:
- No specific dose adjustment is required based solely on age.
- Begin close to the lower end of the dosing range due to potential sensitivity.
Renal Impairment:
- Mild (eGFR 60-89 mL/min/1.73 m²): No adjustment needed.
- Moderate (eGFR 30-59 mL/min/1.73 m²): 25 mg once daily.
- Severe (eGFR 15-29 mL/min/1.73 m²): Use cautiously; max 25 mg daily.
- Very Severe (<15 mL/min/1.73 m²): Not recommended, including end-stage renal disease.
Hepatic Impairment:
- Mild (Child-Pugh A): No dose adjustment is needed.
- Moderate (Child-Pugh B): Do not exceed 25 mg once daily.
- Severe (Child-Pugh C): Not recommended.
Pediatric Use:
- Safety and efficacy not established in children.
How to Take Myrbetriq?
- Take once daily with water.
- Swallow the tablet whole.
- Do not crush, chew, or split the Myrbetriq tablet
- Can be taken with or without food
- Take at approximately the same time each day
- Start with a 25 mg dose, which may increase to 50 mg if needed
- Do not exceed the recommended dose
- If a dose is missed, take it as soon as remembered
- If it’s close to the next dosage, skip the missed dose
- Do not take double doses to make up for a missed one
- Continue taking as prescribed, even if symptoms improve
- Regular follow-ups with your doctor are important
- Inform your medical professional of any side effects or concerns
Missed Dose
If you’ve forgotten to take a dose of Myrbetriq, take it as soon as you remember. If it’s close to the time for your next dose, skip what you missed and maintain your regular dosing routine.
[Note: Do not simultaneously take two doses of Myrbetriq to compensate for a missed dose. This can elevate your risk of experiencing side effects.]
Overdose
An overdose of Myrbetriq (mirabegron) can lead to severe symptoms such as increased heart rate, high blood pressure, and severe headaches. Immediate medical attention is crucial. Treatment may involve supportive care and monitoring in a healthcare facility.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Myrbetriq Work?
Myrbetriq works by stimulating beta-3 adrenergic receptors in the bladder, resulting in the relaxation of the bladder muscle. This reduces urinary urgency, increases bladder capacity, and decreases urination frequency, helping manage overactive bladder symptoms (OAB).
Important Safety Precautions
- Monitor blood pressure regularly
- Use caution in patients with severe uncontrolled hypertension
- Not recommended for severe renal impairment or end-stage renal disease
- Use with caution in severe hepatic impairment
- Avoid in patients with known hypersensitivity to mirabegron
- Use caution in patients with bladder outlet obstruction
- Monitor for signs of urinary retention, especially in men with BPH
- Use caution in patients with narrow-angle glaucoma
- Not recommended during pregnancy unless necessary
- Advise patients to report signs of angioedema (swelling of face, lips, tongue, throat)
- Discontinue if severe hypersensitivity reactions occur
- Practice caution when operating machinery or driving, as dizziness can occur
- Inform the doctor of all medications to avoid potential drug interactions
- Regular follow-up with healthcare providers is important
Storage
- Store Myrbetriq at room temperature, between 20°C to 25°C.
- Keep in a dry place; avoid exposure to moisture.
- Store in the original container, away from direct light.
- Keep the container tightly closed and out of reach of children.
- Follow local regulations for disposing of expired or unused medication.
Myrbetriq Interactions
- CYP2D6 substrates: May increase levels of drugs metabolized by CYP2D6 (e.g., metoprolol, desipramine)
- Digoxin: Myrbetriq may increase digoxin levels
- Antihypertensive medications May enhance blood pressure-lowering effects
- Other beta-3 adrenergic agonists: Avoid concurrent use
- Strong CYP3A4 inhibitors: May increase Myrbetriq levels (e.g., ketoconazole, itraconazole, ritonavir)
- Strong CYP3A4 inducers: May decrease Myrbetriq effectiveness (e.g., rifampin, carbamazepine, phenytoin)
- OCT2 substrates: May increase levels of drugs transported by OCT2 (e.g., metformin)
- Warfarin: Monitor INR when starting or stopping Myrbetriq
- P-glycoprotein substrates: May increase levels of P-gp substrates (e.g., dabigatran)
- Alcohol: No known significant interaction
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]
Myrbetriq Alternatives
- Oxybutynin (ditropan, oxytrol)
- Tolterodine (detrol, detrol la)
- Solifenacin (vesicare)
- Trospium (sanctura)
- Fesoterodine (toviaz)
- Darifenacin (enablex)
- Propiverine (not widely branded)
- Mirabegron and Solifenacin Combination (no specific brand)
[Note: Your healthcare provider will choose which Myrbetriq alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
How soon can I expect to see results from Myrbetriq?
You may notice an improvement in your overactive bladder (OAB) symptoms within 4 to 8 weeks. Even if there is no immediate improvement in the initial weeks, it’s crucial to keep taking Myrbetriq consistently.
Can taking Myrbetriq lead to weight gain?
Weight gain has not been indicated as a side effect in clinical studies of Myrbetriq. If you experience significant weight gain while on this medication, it is suggested to consult with your healthcare provider. They can help determine the cause of the weight gain and decide if further medical evaluation is needed. Maintaining a healthy weight is very important, as getting over weight may exacerbate symptoms of an overactive bladder, although additional research is required to fully understand this relationship.
Will Myrbetriq increase the frequency of urination?
No, Myrbetriq does not cause increased urination. Instead, it treats an overactive bladder by relaxing the bladder muscles, enabling it to hold more urine. This actually reduces the frequency of bathroom visits.
Is Myrbetriq classified as an anticholinergic drug?
No, Myrbetriq is not an anticholinergic medication. It is a beta-3 adrenergic agonist, which works differently from anticholinergic medicines for overactive bladder, such as oxybutynin (Ditropan). Consequently, Myrbetriq does not typically cause anticholinergic side effects like dry mouth and dizziness.
Our Guarantee
At Arctic Meds, we guarantee you will find the most competitive prices for purchasing Myrbetriqthrough our platform. As the best Canadian online pharmacy, we are dedicated to delivering only the top-most quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Myrbetriq online from Canada at a low price, contact us.
