Eluxadoline
Buy Viberzi Online at Affordable Price
Viberzi (Eluxadoline) is an FDA-approved medication prescribed for adults to manage irritable bowel syndrome with diarrhea (IBS-D). It works by modulating opioid receptors in the gastrointestinal tract, helping to reduce bowel contractions and abdominal pain. Available in 75 mg and 100 mg extended-release tablets, Viberzi should be taken twice daily with food. Common side effects include gas, dizziness, and constipation. It’s crucial not to exceed the prescribed dosage to avoid severe side effects like pancreatitis. Viberzi is not suitable for patients without a gallbladder, those with certain pre-existing conditions, or individuals under 18.
Product Overview
Viberzi is a prescription drug formulated to manage symptoms of irritable bowel syndrome with diarrhea (IBS-D) in adults. It functions as a mixed opioid receptor modulator, acting both as an agonist and antagonist at opioid receptors specifically located in the gastrointestinal tract. This dual action helps to moderate bowel motility and decrease fluid secretion in the gut, effectively reducing the frequency and severity of diarrhea and abdominal pain associated with IBS-D.
Viberzi is available in two strengths: 75 mg and 100 mg extended-release tablets. The typical adult dosage is 100 mg, taken twice daily with food, while seniors may be prescribed either 75 mg or 100 mg depending on their condition and response to treatment. The medication must be swallowed whole with water and should not be crushed or chewed. Side effects of Viberzi can include dizziness, constipation, nausea, headache, and abdominal discomfort. It is contraindicated in individuals without a gallbladder, those with a history of pancreatitis, or with severe liver impairment.
Patients are advised to store Viberzi at room temperature in its original packaging to protect it from light and moisture. It should be kept out of reach of children and not stored in humid environments like bathrooms. Always consult a healthcare provider before starting Viberzi, especially to discuss potential interactions with other medications such as antidepressants, pain relievers, and certain vitamins.
Uses of Viberzi
- Treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.
[Important Warning: It is important to note that Viberzi is not approved for use in individuals younger than 18 years old.]
Benefits of Viberzi
- Effective in treating diarrhea-predominant irritable bowel syndrome (IBS-D) in adults.
- Helps reduce the severity and frequency of abdominal pain associated with IBS-D.
- Can improve stool consistency and reduce the urgency to have bowel movements.
- May help patients better manage their IBS-D symptoms and improve quality of life.
- Acts as a mu-opioid receptor agonist, which can slow intestinal motility and decrease fluid secretion in the gut.
- Generally well-tolerated, with a low risk of serious side effects when used as directed.
- Available in an extended-release oral tablet formulation for convenient once-daily dosing.
- Provides an effective treatment option for those who have not responded well to other IBS-D medications.
- Can be used as a long-term maintenance treatment for IBS-D.
- Does not require any invasive procedures or surgeries.
- May help reduce the need for over-the-counter or prescription anti-diarrheal medications.
Side Effects of Viberzi
Common side effects of Viberzi may include:
- Gas
- Dizziness
- Constipation
- Nausea
- Runny or stuffy nose
- Abdominal pain or discomfort
- Vomiting
- Headache
- Fatigue
- Bloating
- Indigestion
- Dry mouth
[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
Viberzi Dosage
Forms & Strengths
It comes in the form of an oral tablet and has these following strengths:
- Viberzi 75 mg tablets
- Viberzi 100 mg tablets
Recommended Dosages
Dosage for IBS-D (Irritable Bowel Syndrome with Diarrhea)
- Recommended Dosage for Adults: Take 100 mg two times daily with food.
- Recommended Dosage for Seniors: Take 75 mg or 100 mg two times daily.
How to Take Viberzi?
- Take Viberzi tablets orally with food to enhance absorption and reduce stomach upset.
- Swallow the tablet whole with water. Do not split, crush, or chew the tablet, as this can affect how the medication is released and absorbed by your body.
- The typical dosage is one tablet taken twice daily.
- Aim to take Viberzi at evenly spaced intervals, approximately 12 hours apart, to maintain steady medication levels in your body.
- Strictly adhere to the dosage and administration instructions provided by your healthcare professional.
- Only take the dosage recommended by your doctor to avoid potential risks or side effects.
Missed Dose
If you forget to take a dose of Viberzi, take it as soon as you remember. Do not take two doses at the same time to make up for the missed dose.
[Note: Do not take two doses of Viberzi at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]
Overdose
Overdosing on Viberzi can lead to serious health issues, including:
- Severe constipation
- Nausea and vomiting
- Abdominal pain or cramping
- Dizziness or lightheadedness
- Difficulty breathing
- Changes in heart rate or rhythm
- Confusion or disorientation
- Loss of consciousness
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Viberzi Work?
Viberzi operates through a unique mechanism as a mixed opioid receptor modulator. It simultaneously acts as both an agonist and antagonist on opioid receptors located specifically in the gastrointestinal tract. By targeting these receptors, Viberzi effectively reduces bowel contractions, which helps alleviate abdominal pain and discomfort. This action results in improved control over bowel habits for individuals suffering from irritable bowel syndrome with diarrhea (IBS-D).
Important Safety Precautions
Always consult your doctor before taking Viberzi as it may cause the following:
- Adverse Reactions in Pediatric Patients
- Interactions with Alcohol
- Hepatic Impairment
- Severe Allergic Reactions
- Spasm of the Sphincter of Oddi
- Breastfeeding
- Constipation Risk
- Pregnancy
- Pancreatitis Risk
Storage
- Store Viberzi at room temperature, away from excessive heat and moisture.
- Keep the tablets in their original packaging to protect them from light.
- Ensure the medication is stored in a child-resistant container and kept out of reach of children.
- Do not store Viberzi in the bathroom or other humid environments to maintain its stability.
Viberzi Interactions
- Buspirone
- Lyrica (pregabalin)
- Vitamin D3 (cholecalciferol)
- Omeprazole
- Cyclobenzaprine
- Tramadol
- Gabapentin
- Atorvastatin
- Alcohol
- Levothyroxine
- Cymbalta (duloxetine)
- Lisinopril
- Amitriptyline
- Prednisone
- Zyrtec (cetirizine)
- Dicyclomine
- Trazodone
- Vitamin B12 (cyanocobalamin)
- Amlodipine
- Metformin
- Lomotil (atropine/diphenoxylate)
- Meloxicam
- Famotidine
- Ibuprofen
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Viberzi Alternatives
- Lotronex (alosetron)
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- Lyrica (pregabalin)
- Xifaxanta (rifaximin)
- Imodium (loperamide)
- Elavil (amitriptyline hydrochloride)
- Lomotil (atropine and diphenoxylate)
- Prednisone (prednisone)
- Welchol (colesevelam)
[Note: Your healthcare provider will choose which Viberzi alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
Who should not take Viberzi?
Viberzi should not be used by individuals with certain conditions due to the risk of serious side effects. It is contraindicated for:
- Individuals without a Gallbladder
- Biliary Duct Obstruction or Sphincter of Oddi Dysfunction
- Structural Diseases of the Pancreas
- History of Pancreatitis
- Alcohol Consumption
Can I stop taking Viberzi if my symptoms improve?
No, you should not stop taking Viberzi on your own, even if your symptoms improve. It’s crucial to follow your healthcare provider’s instructions and complete the full course of treatment prescribed. Discontinuing Viberzi without guidance from your doctor can lead to a return of symptoms. Always consult with your healthcare provider before making any changes to how you take your medication.
How long can you stay on Viberzi?
You can continue taking Viberzi for as long as your doctor recommends it. It’s important to closely follow your doctor’s instructions regarding the duration of treatment. Make sure to monitor your supply of Viberzi and contact your healthcare provider to refill your prescription before you run out. This ensures that you do not miss any doses and maintain consistent treatment for your condition.
When is the best time to take Viberzi?
The best time to take Viberzi is twice a day with meals to enhance absorption and reduce potential stomach upset. A convenient way to remember your doses is to take one tablet in the morning with your breakfast and another tablet in the evening with your dinner. This routine helps maintain a consistent level of medication in your system and aligns with your daily meal schedule, making it easier to remember each dose.
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