Estradiol

Buy Vagifem Online from Trusted Canadian Pharmacy

Vagifem is an FDA-approved vaginal estrogen tablet designed to alleviate symptoms of vaginal atrophy in menopausal women, such as dryness and irritation. It offers localized treatment with minimal systemic absorption and is available in various forms, including creams, inserts, and rings. Always consult a healthcare provider to ensure it suits your needs and monitor for potential side effects.

Product Overview 

Vagifem is a low-dose vaginal estrogen tablet specifically designed to treat symptoms of vaginal atrophy due to menopause. It is effective in alleviating symptoms such as vaginal dryness, itching, and irritation by delivering estrogen directly to the vaginal tissue. This localized approach not only helps restore the vaginal tissue’s thickness and elasticity but also minimizes systemic absorption, reducing the chances of side effects associated with higher doses of estrogen.

Available in forms like vaginal creams (Estrace, Premarin), vaginal inserts (Imvexxy, Vagifem, Yuvafem), and vaginal rings (Estring, Femring), Vagifem offers flexibility in administration, catering to individual preferences and medical needs. The typical initial dosage is 10 mcg administered on a daily basis for two weeks, followed by a maintenance dose of 10 mcg twice weekly. 

Patients are advised to regularly consult with their healthcare provider to monitor effectiveness and adjust the regimen. Safety precautions include avoiding use during pregnancy, understanding potential risks such as endometrial or breast cancer, and watching for symptoms like unusual vaginal bleeding. Always check interactions with other medications and follow storage guidelines to maintain efficacy.

Uses of Vagifem 

• Osteoporosis
• Menopause
• Estrogen Replacement
• Atrophic Vaginitis

Benefits of Vagifem 

• Relieves Vaginal Symptoms
• Improves Comfort
• Localized Treatment
• Effective Maintenance

Side Effects of Vagifem 

Common side effects of Vagifem may include:

• Stomach cramps
• Nausea
• Vomiting
• Bloating
• Diarrhea
• Breast swelling or tenderness
• Nipple discharge
• Vaginal itching or discharge
• Ankle or foot swelling
• Headaches, including migraines
• Weight fluctuations
• Dizziness
• Cold-like symptoms (stuffy nose, sneezing, sore throat)
• Acne
• Changes in skin color
• Increased facial hair
• Thinning hair on the scalp
• Depression
• Altered menstrual periods
• Breakthrough bleeding

[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Vagifem Dosage

Forms & Strengths

Vagifem comes in the following forms and strengths:

Vaginal Cream

• Estrace Vaginal Cream: 0.1 mg/g (0.01%)

Vaginal Inserts

• Imvexxy: 4 mcg
• Imvexxy, Vagifem, Yuvafem: 10 mcg

Vaginal Rings

• Estring: Contains 2 mg of estradiol per ring, releasing approximately 7.5 mcg every 24 hours
• Femring:
  • 12.4 mg per ring, releasing 0.05 mg every 24 hours over three months
  • 24.8 mg per ring, releasing 0.1 mg every 24 hours over three months

Recommended Dosages

• Initial Treatment: Administer 10 mcg vaginally each day for two weeks.
• Maintenance Dose: Apply 10 mcg vaginally twice a week (e.g., every Monday and Thursday).
• Alternative Low Dose: Post-initial phase, use 10 mcg vaginally once a week, adjusted based on symptom control.

How to Take Vagifem? 

• Ensure Vagifem is not past its expiration date.
• Before and after application, wash your hands thoroughly.
• Remove an applicator from the package; the tablet should be loaded inside.
• You may stand with one foot on a chair or lie back with your knees bent.
• Carefully insert the applicator into your vagina to a comfortable depth.
• Press the plunger of the applicator until it stops to release the tablet.
• Slowly pull the applicator out and dispose of it properly; do not reuse it.
• Use Vagifem at the same time each day for the best results.

Missed Dose 

If you miss a dose of Vagifem, take it when you remember. If it’s close to the time for your next dose of Vagifem, skip the missed one and continue as scheduled.

 

[Note: Do not simultaneously take two doses of Vagifem to compensate for a missed dose. This can escalate your risk of experiencing side effects.]

Overdose

In case of a Vagifem overdose, seek immediate medical attention, although severe symptoms from overdose are unlikely due to its local application.

 

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Vagifem Work?

Vagifem works by delivering estrogen directly to the vaginal tissue. It helps to restore the vaginal tissue’s thickness and elasticity, which can decrease with age or due to lower estrogen levels after menopause. This localized delivery minimizes systemic absorption, effectively alleviating signs of vaginal atrophy, such as dryness, itching, and irritation, while also reducing the risk of systemic side effects.

Important Safety Precautions 

• Always start treatment after a thorough consultation with your healthcare provider.
• Use Vagifem precisely as prescribed, without altering the dose or frequency.
• Schedule routine visits with your doctor to monitor your response to treatment and adjust the regimen as needed.
• Be vigilant for symptoms like unusual vaginal bleeding, new breast lumps, or vision changes, and report them to your doctor immediately.
• Understand the potential risks of endometrial cancer or breast cancer associated with hormonal treatments.
• Do not use Vagifem if you are pregnant, suspect you might be, or if you are breastfeeding.
• Tell your doctor about all other medications you’re taking to avoid possible drug interactions.
• Smoking increases the risk of severe cardiovascular side effects from hormonal therapy.
• For safety, check and adhere to the expiration date on the package.

Storage 

• Store Vagifem at room temperature, typically between 68°F to 77°F.
• Protect from excessive heat and moisture. Do not store in the bathroom or near a heat source.
• Retain the tablets in their original box to protect them from light and moisture until use.
• Ensure Vagifem is kept out of reach of children and pets to avoid accidental ingestion.
• Check the expiration date regularly and dispose of expired tablets according to local guidelines.

Vagifem Interactions 

• Blood Thinners (Anticoagulants): Estrogen can potentially reduce the effectiveness of warfarin and similar blood-thinning medications, which may necessitate dosage adjustments.
• Thyroid Medications: Estrogen may increase thyroid-binding globulin levels, affecting the dosage needed for thyroid hormone replacement therapy.
• Grapefruit Juice: Consuming grapefruit juice can increase blood levels of estrogen, potentially enhancing side effects.
• Corticosteroids: Estrogen may alter the metabolism and excretion of corticosteroids, impacting their therapeutic effects.
• Other Hormones: Concurrent use with other hormonal therapies, like progestins or other forms of estrogen, may alter the effects and side effects of Vagifem.
• St. John’s Wort: This herbal supplement may decrease the effectiveness of estrogen therapies, including Vagifem, by increasing the metabolism of estrogens in the liver.
• CYP3A4 Inducers: Drugs that induce CYP3A4 enzymes, like certain anticonvulsants and antibiotics, can decrease estrogen levels, reducing Vagifem’s effectiveness.

 

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

Vagifem Alternatives 

• Estrace Vaginal Cream (estradiol vaginal cream)
• Premarin Vaginal Cream (conjugated estrogens vaginal cream)
• Estring (estradiol vaginal ring)
• Femring (estradiol acetate vaginal ring)
• Imvexxy (estradiol vaginal inserts)
• Intrarosa (prasterone vaginal inserts)
• Osphena (ospemifene – non-estrogen oral tablet)
• Estrogel (estradiol topical gel)
• Divigel (estradiol topical gel)
• Evamist (estradiol transdermal spray)
• Mimvey (estradiol vaginal emulsion)
• Estraderm (estradiol transdermal patch)
• Vivelle-Dot (estradiol transdermal patch)

[Note: Your healthcare provider will choose which Vagifem alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions 

Can Vagifem lead to hair loss?

Hair loss can occur as a potential side effect of using generic estradiol, Vagifem, or Yuvafem, although it typically isn’t severe. If you experience significant hair loss or notice bald patches after starting this medication, it’s important to consult your healthcare provider.

What is the safe duration for using Vagifem?

The safe duration for taking estradiol varies, as long-term use of estrogen replacement therapies, including estradiol, increases the potential for severe health issues like breast cancer and blood clots. Research indicates that using low-dose estradiol vaginal inserts (10 mcg) for up to a year poses a very low risk compared to higher-dose oral pills. However, it’s crucial to discuss your specific risks with your healthcare expert to figure out the appropriate length of time you should use this medication.

When is the best time of day to take estradiol?

Estradiol can be taken at any time of day that fits your schedule. Although many individuals choose to apply it at bedtime, this is not required. For the most consistent results, using it simultaneously each day is essential.

How long should I use hormone replacement therapy (HRT)?

HRT is recommended for 2 to 5 years to alleviate symptoms, but it may be necessary to continue it longer. There is no absolute limit on the duration of HRT use. It is important to consult with your doctor at least annually to assess if the benefits of using vaginal estrogen continue to outweigh the risks.

Our Guarantee

At Arctic Meds, we guarantee that you will find the most competitive prices for purchasing Vagifem through our platform. As the best Canadian online pharmacy, we are committed to providing only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Vagifem online from Canada at a low price contact us.