Plecanatide
Trulance
Trulance is approved by the FDA to treat adult constipation types such as Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC). It effectively alleviates symptoms by increasing intestinal fluid, promoting easier bowel movements. Trulance is convenient for daily use, doesn’t require food, and is minimally absorbed into the bloodstream, reducing severe side effects and improving overall quality of life for individuals with chronic constipation or IBS-C.
Product Overview
Trulance, an oral medication known as plecanatide, is specifically designed to manage severe constipation types in adults, including Chronic Idiopathic Constipation (CIC) and Irritable Bowel Syndrome with Constipation (IBS-C). Approved by the FDA, Trulance enhances fluid in the intestines, facilitating smoother and easier bowel movements, often showing effectiveness within the first week of treatment.
This medication aims to establish more regular bowel patterns and is taken once daily, with or without food, adding convenience to its use. Trulance’s mechanism involves mimicking a natural protein in the gut, binding to intestinal cell receptors to promote fluid absorption and ease stools.
It has a favorable safety profile, primarily acting locally within the gastrointestinal tract without significant absorption into the bloodstream. This feature allows for long-term management of constipation symptoms with a low risk of severe side effects, substantially improving patients’ quality of life while managing conditions like IBS-C and CIC effectively.
What Are the Uses of Trulance?
- Irritable Bowel Syndrome with Constipation (IBS-C)
- Chronic Idiopathic Constipation (CIC)
What Are the Benefits of Trulance?
- Effectively treats chronic idiopathic constipation (CIC) in adults.
- Helps relieve constipation symptoms associated with irritable bowel syndrome (IBS-C).
- Works by increasing fluid in the intestines, making bowel movements easier.
- Generally produces results within the first week of treatment.
- Can help establish more regular bowel movements.
- Once-daily dosing makes it convenient to take.
- Does not need to be taken with food.
- May reduce abdominal pain and discomfort associated with constipation.
- Generally well-tolerated with a low risk of severe side effects.
- Does not get absorbed into the bloodstream, working locally in the gut.
- Can be used for long-term management of chronic constipation.
- May improve quality of life for people with chronic constipation or IBS-C.
What Are the Side Effects of Trulance?
Common Trulance side effects may include:
- Abdominal bloating or tenderness
- Infections, such as urinary tract infection or common cold
- Mild diarrhea
- Dizziness
- Nausea
[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
What Are the Forms & Strengths of Trulance?
Trulance comes in the form of oral tablet and is available in a strength of:
- 3 mg
What Is the Typical Dosage of Trulance?
Dosage for Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC):
- Usual Dose: The standard dosage for Trulance is 3 mg taken once daily.
- Maximum Dose: The maximum recommended dose is also 3 mg once daily.
How to Take Trulance?
- Administration: Swallow Trulance tablets whole; do not split or chew. You can take the medication with or without food.
- Frequency: Take Trulance once daily. Choose a time that suits you, but for best results, take it at the same time each day.
- If Difficulty Swallowing: If you have trouble swallowing the tablets, you might be able to crush them and mix with applesauce or water. Always confirm this method with your doctor or pharmacist.
- Accessibility: If you have trouble reading the label or opening the bottle, ask your pharmacist for accessible labels and easy-open containers.
- Reminders: To avoid missing doses, use medication reminders such as alarms, timers, or reminder apps.
What to Do When You Miss a Dose of Trulance?
- If you miss a dose and it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take extra doses to make up for the missed one.
[Note: Do not take two doses of Trulance at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]
What Happens When You Overdose on Trulance?
Do not exceed the prescribed dose. Overdosing can cause severe side effects. If you suspect an overdose, contact your doctor immediately, call America’s Poison Centers at 800-222-1222, or seek emergency medical attention.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Trulance Work?
Trulance mimics a natural protein in the digestive system that binds to receptors in the small intestine, increasing fluid absorption which helps form stools and facilitates smoother bowel movements. Users often experience relief from constipation within a week of starting treatment.
What Are the Important Safety Precautions of Trulance?
- Allergies and Intestinal Blockage: Do not use Trulance if allergic to plecanatide or if you have an intestinal blockage, as it may cause severe complications.
- Age Restrictions: Not for children under 6 due to severe dehydration risks; not recommended for those under 18.
- FDA Boxed Warning: Trulance has a boxed warning for the risk of severe dehydration in children, reflecting serious potential side effects.
- Pregnancy and Breastfeeding: Safety during pregnancy and breastfeeding is not established. Discuss risks and necessary precautions with your doctor.
- Medical History: Inform your doctor about any medical conditions, especially bowel obstructions or past allergic reactions to medications.
- Birth Control: Discuss birth control options if there’s a risk of pregnancy during treatment, as the safety of Trulance in pregnancy is uncertain.
How Do You Store Trulance?
- Store at room temperature, 68–77°F (20–25°C). Temporary storage between 59–86°F (15–30°C) is acceptable during travel.
- Keep the tablets in their original packaging to protect from light.
- Avoid storing in damp or moist areas such as bathrooms.
- Dispose of any unused medication safely to prevent accidental ingestion and environmental harm.
What Drugs Interact with Trulance?
This drug is not known to interact with other medications.
[Note: Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]
What Are the Trulance Alternatives?
- Citrucel (methylcellulose)
- Senokot (senna)
- Linzess (linaclotide)
- Colace (docusate)
- Magnesium citrate
- Tegaserod
- Dulcolax (bisacodyl)
- Amitiza (lubiprostone)
- Metamucil (psyllium)
[Note: Your healthcare provider will choose which Trulance alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Trulance Cost & Coupons
Trulance, prescribed for chronic idiopathic constipation, can be costly in the U.S., with prices frequently soaring without insurance. Arctic Meds mitigates this expense by offering the option to buy Trulance online from Canada at substantially lower costs. This initiative ensures affordable healthcare solutions for U.S. residents. Use the Trulance coupon code ARCTIC10 to enjoy an extra 10% off your first order. Additionally, participating in our referral program may reduce your medication expenses by up to $200, enhancing your overall savings.
Frequently Asked Questions
How long does it take for Trulance to work?
Trulance does not produce immediate effects. Typically, it starts to alleviate constipation within about one week of starting treatment.
Do you have to drink a lot of water with Trulance?
Yes, it’s important to stay well-hydrated while taking Trulance. The medication can cause severe diarrhea, which may lead to life-threatening dehydration. Drinking plenty of fluids can help mitigate this risk.
Does Trulance help with gas and bloating?
Trulance is effective in treating symptoms of irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation, including bloating and stomach pain. However, be aware that it can also cause diarrhea as a side effect.
Should I take Trulance at night?
Trulance can be taken at any time of the day that suits you. Ensure to swallow the tablet whole; do not crush it. If you have difficulty swallowing pills, alternative instructions are available for administering the medication.
Our Guarantee
At Arctic Meds, we guarantee that you will find the most competitive prices to buy Trulance online through our platform. As the best Canadian online pharmacy, we are committed to delivering only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. To seamlessly buy Trulance online from Canada at a low price contact us.