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Levothyroxine Sodium


Thyrox is an FDA-approved medication containing Levothyroxine Sodium, a synthetic thyroid hormone. It’s prescribed for hypothyroidism, goiter, and certain thyroid cancers. Supplementing insufficient thyroid hormone restores normal levels and relieves associated symptoms, regulating metabolism and energy levels. It is available in tablet form with various strengths, including 25mcg, 50mcg, and 100mcg. It is typically taken orally once daily on an empty stomach. The recommended dosage varies based on individual response. Side effects may include temporary hair loss, changes in appetite, weight fluctuations, and mild gastrointestinal symptoms. It’s crucial to inform your doctor about existing medical conditions, allergies, or medications to avoid interactions. In case of a missed dose, take it promptly unless close to the next dose. Store at room temperature, away from heat, moisture, and children. Follow your healthcare provider’s guidance for safe use.

Product Overview

Thyrox is an FDA-approved medication primarily composed of the active ingredient Levothyroxine Sodium, a synthetic form of the thyroid hormone thyroxine (T4). Levothyroxine is commonly prescribed for individuals with hypothyroidism, a condition in which the thyroid gland is unable to produce enough thyroid hormone. It is also utilized in cases of goiter, an enlarged thyroid gland, and certain thyroid cancers. 

Levothyroxine works by supplementing the insufficient thyroid hormone in the body, thereby restoring normal thyroid hormone levels and relieving symptoms associated with hypothyroidism. By mimicking the action of the natural hormone, it helps regulate metabolism, energy levels, and other bodily functions affected by thyroid hormone imbalance.

Thyrox is available in several strengths, like 25 mcg, 50 mcg, and 100 mcg per tablet. It is typically taken orally, usually once daily, preferably in the morning on an empty stomach, at least 30 minutes before breakfast. The dosage may vary based on individual response and the healthcare provider’s recommendation. Common side effects of Thyrox 50 tablets may include temporary hair loss, changes in appetite, weight fluctuations, and mild gastrointestinal symptoms.

It’s crucial to let your doctor know about your existing medical conditions, allergies, or medications, as they may interact with levothyroxine. In case of a missed dose, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to catch up. Store Thyrox at room temperature, away from heat, moisture, and children. It’s crucial to follow your healthcare provider’s guidance and consult them before changing the dosage or stopping taking the Thyrox 50 composition.

Uses of Thyrox

  • Thyrox is used for the treatment of hypothyroidism (reduced levels of thyroid hormone).

How to Use Thyrox?


Strengths and Forms

Thyrox is commonly available in tablet form, including strengths like:

  • Thyrox 25 mcg tablet
  • Thyrox 50 mcg tablet
  • Thyrox 100 mcg tablet

Recommended Dosage for Hypothyroidism

For Adult (18–49 Years):

  • The typical recommended dosage is 1.6 mcg/kg daily.
  • The maximum dose is 200 mcg daily.

For Children (0–17 Years):

  • The doctor decides the dosage based on weight and thyroid hormone levels.

For Seniors (50 Years and Older):

  • The typical initial dosage is 12.5–25 mcg/day.
  • Your doctor may modify your dosage every 6–8 weeks based on your thyroid hormone lab results.

Recommended Dosage for Goiter

For Adults (18 Years and Older):

  • Your doctor recommends your dosages based on your thyroid hormone level.

For Children (0–17 Years):

  • Not recommended.

Recommended Dosage for Thyroid Cancer

For Adults (18 Years and Older):

  • Your doctor adjusts your Thyrox 50 composition based on your thyroid hormone level.

For Children (0–17 Years):

  • Not recommended.

Dosing Modifications

For Pregnant Women:

  • Your doctor may recommend a higher dosage of levothyroxine.

For People with Cardiovascular Issues:

  • Your doctor may prescribe an initial dosage of 12.5–25 mcg daily.
  • Your doctor may adjust the dosage every 6–8 weeks.

[Note: Remember, these recommendations may vary from person to person. Discuss it with your doctor, and they’ll customize your Thyrox dosage accordingly.]

How to Take It?

  • Take Thyrox tablets at the same time each day to maintain constant levels of thyroid hormone in your body.
  • Take Thyrox on an empty stomach, preferably 30 minutes- 60 minutes before breakfast or at least 3-4 hours after eating.
  • Swallow Thyrox tablets whole with a full glass of water. Avoid chewing or crushing the tablets.
  • Wait at least 4 hours before taking other medications that may interfere with Thyrox absorption, such as calcium or iron supplements, antacids, or certain foods high in fiber or soy.
  • Follow up with your healthcare professional regularly for thyroid function tests to ensure your Thyrox dosage is appropriate and to monitor for any side effects of Thyrox 50 tablets or changes in your condition.
  • Do not stop taking Thyrox abruptly without discussing it with your healthcare professional, as this can cause symptoms of hypothyroidism to return or worsen.

[Note: Your doctor will decide the suitable Thyrox 50 composition for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Thyrox Work?

Thyrox is a synthetic form of the thyroid hormone thyroxine (T4). It works by supplementing the insufficient thyroid hormone in individuals with hypothyroidism, a state where your thyroid gland is unable to generate sufficient thyroid hormone. Thyrox increases thyroid hormone levels in the body, which helps regulate metabolism, energy production, and various bodily functions. By restoring normal thyroid hormone levels, Thyrox alleviates symptoms of hypothyroidism.

Important Safety Information

Side Effects

Common side effects of Thyrox may include:

  • Nausea
  • Headache
  • Fatigue
  • Insomnia
  • Weight changes (either loss or gain)
  • Sweating
  • Increased appetite
  • Shakiness
  • Nervousness
  • Changes in menstrual periods

Mild side effects of Thyrox may include:

  • Hair loss
  • Flushing
  • Stomach upset
  • Diarrhea or constipation
  • Tremors
  • Muscle weakness
  • Allergic reactions (rare)

Serious side effects of Thyrox may include:

  • Chest pain or rapid heartbeat (palpitations)
  • Difficulty breathing
  • Severe headache
  • Signs of allergic reaction (rash, itching, swelling of the face/tongue/throat, severe dizziness)
  • Changes in mood (depression, anxiety)
  • Signs of overactive thyroid (increased sweating, sensitivity to heat, diarrhea, weight loss)
  • Signs of underactive thyroid (extreme fatigue, sensitivity to cold, dry skin, constipation)
  • Seizures
  • Irregular heartbeat
  • Swelling of the ankles/feet
  • Yellowing of the eyes/skin (jaundice)
  • Worsening of diabetes control (increased thirst, increased urination, unexplained weight loss)
  • Adrenal insufficiency (fatigue, weakness, nausea, vomiting)
  • Bone pain or fractures (in long-term use, at high doses)

[Note: Remember, this list may not cover all possible side effects of Thyrox 50 tablets. Always consult with your healthcare giver for medical advice about side effects.]


Cardiac Adverse Reactions in the Elderly and Patients with Underlying Cardiovascular Disease: Overtreatment with Thyrox can lead to heightened heart rate, increased cardiac wall thickness, and contractility, potentially triggering angina or irregular heart rhythms, especially in individuals with cardiovascular issues or elderly patients. It’s advisable to commence Thyrox therapy at lower doses in these groups and monitor for cardiac arrhythmias during surgical treatments in patients with coronary artery disease. If cardiac symptoms worsen, dose reduction or temporary discontinuation may be necessary.

Myxedema Coma: The condition is marked by poor circulation and reduced metabolism, representing a critical emergency. Oral Thyrox products aren’t recommended for treating myxedema coma; instead, opt for intravenously administered thyroid hormone products.

Acute Adrenal Crisis in People with Concomitant Adrenal Insufficiency: In patients with adrenal insufficiency, thyroid hormone therapy can increase the clearance of glucocorticoids, potentially causing an acute adrenal crisis. Thus, ensure patients with adrenal insufficiency receive replacement glucocorticoids before starting Thyrox therapy.

Prevention of Hyperthyroidism: Incorrect dosing of Thyrox may adversely impact various bodily functions, including growth, cardiovascular health, bone metabolism, reproductive function, cognitive function, emotional well-being, gastrointestinal health, and glucose and lipid metabolism. Careful dose titration and monitoring are essential to avoid these effects, along with vigilance for potential drug or food interactions.

Worsening of Diabetic Control: The introduction of Thyrox therapy in individuals with diabetes mellitus may exacerbate glycemic control, necessitating adjustments to antidiabetic medications or insulin. Regular monitoring of glycemic control is vital when initiating, altering, or discontinuing Thyrox therapy.

Decreased Bone Mineral Density Linked with Thyroid Hormone Over-Replacement: Excessive thyroid hormone replacement with Thyrox may lead to improved bone resorption and reduced bone mineral density, particularly in post-menopausal women. Administering the minimum effective Thyrox dose to achieve desired clinical and biochemical responses can help mitigate this risk.

Not for Obesity or Weight Loss

Thyrox should not be used to treat obesity or for weight loss purposes. While thyroid hormones play a role in regulating metabolism, using Thyrox solely for weight reduction is not only ineffective but also potentially harmful. Inappropriate use of Thyrox for weight loss can lead to adverse effects, including cardiac complications, bone density issues, and metabolic imbalances. 


  • Take Thyrox precisely as your doctor prescribed; never adjust the dosage on your own.
  • Keep your doctor informed about any medical conditions you have before starting Thyrox.
  • Ensure you’re aware of potential interactions between Thyrox and other medications or supplements you’re taking. Discuss these with your doctor.
  • Monitor your thyroid function regularly as your doctor advises while taking Thyrox.
  • If you experience any unusual symptoms like rapid heartbeat or chest pain, notify your doctor immediately.
  • Avoid consuming excessive amounts of iodine-rich foods while taking Thyrox.
  • Store Thyrox at room temperature, away from moisture and heat, and out of reach of children and pets.
  • You are advised to take a missed dose as soon as you remember. However, do not double the dose if you are close to the next scheduled dose.
  • Before undergoing any medical procedures or surgeries, inform the healthcare provider about your Thyrox medication.
  • Discuss the potential impact of Thyrox on pregnancy or breastfeeding with your doctor if you’re planning to conceive or are pregnant or breastfeeding.

Thyrox Contraindications

  • Allergic to Levothyroxine or any other ingredients used in Thyrox.
  • Disorders related to the adrenal glands.
  • Thyrotoxicosis (high level of thyroid hormone in the bloodstream).

Missed Dose

If you forget to take a dose of Thyrox, take it as soon as you recall. But if it’s almost time for your next dose, skip the missed one and resume your usual dosing routine. Avoid taking an extra dose to compensate for the missed one.

[Note: If you have missed a dose of Thyrox tablets and are still determining when to take the next one, immediately consult your doctor or pharmacist.]


Thyrox overdose can lead to severe complications. Symptoms may include rapid heartbeat, sweating, tremors, anxiety, weight loss, and heat intolerance. In severe but rare cases, it may lead to cardiac arrhythmias, heart failure, or coma.

[Note: If you consumed more than recommended doses of Thyrox, get medical help right away, or call the Poison Help line at 1-800-222-1222.]


  • Store Thyrox at room temperature, away from moisture and heat.
  • Keep it in its original packaging, tightly closed.
  • Avoid exposure to direct sunlight.
  • Keep it out of reach of children and pets.
  • Discard any expired medicine.

[Note: Discuss with your healthcare professional about the proper disposal of any unused Thyrox tablets and any questions you may have regarding their storage.]

Thyrox Interactions

  • Cholestyramine
  • Colestipol
  • Colesevelam
  • Antacids
  • Sucralfate
  • Simethicone
  • Iron supplements
  • Sodium polystyrene sulfonate
  • Calcium supplements
  • Orlistat
  • Sucroferric oxyhydroxide
  • Lanthanum
  • Sevelamer

[Note: This isn’t a complete list, and there could be other drugs that interact with Thyrox. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Thyrox Alternatives

  • Cytomel (liothyronine sodium)
  • Thyrolar (liotrix sodium)
  • Eltroxin (levothyroxine sodium)
  • Ermeza (levothyroxine sodium)
  • Euthyrox (levothyroxine sodium)
  • Eutroxsig (levothyroxine sodium)
  • Evotrox (levothyroxine sodium)
  • Levo-T (levothyroxine sodium)
  • Levolet (levothyroxine sodium)
  • Levoxyl (levothyroxine sodium)

[Note: Your doctor will choose the best Thyrox alternative for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Frequently Asked Questions

How long does it take for Thyrox to work?

Thyrox begins working immediately. However, noticeable symptom improvement may take several weeks. Factors influencing response time include starting dose, use of T3 medication, and overall lifestyle. Regular blood tests help adjust dosage for optimal thyroid hormone levels.

Can I take Thyrox for weight loss?

Thyrox is not recommended for weight loss. It is primarily used to treat underactive thyroid (hypothyroidism) by supplementing thyroid hormones. While some people may experience weight changes due to improved metabolism, using Thyrox solely for weight loss is inappropriate and potentially harmful. Always discuss with a healthcare professional for individualized advice regarding weight management and medication use.

Can I stop taking Thyrox once my symptoms improve?

No, you should not stop taking Thyrox once your symptoms improve. Continuing the medication as prescribed by your healthcare provider is crucial to maintain optimal thyroid function and prevent symptom recurrence. Always consult your doctor before making any changes to your medication regimen. 

Can Thyrox 50 mcg tablets cause hair loss?

Yes, Thyrox 50 mcg may cause hair loss in some individuals. Changes in thyroid hormone levels can affect hair growth cycles, leading to temporary hair loss. If you experience this side effect, consult your healthcare provider.

Can I take Thyrox during pregnancy?

Yes, Thyrox can be taken during pregnancy, but it’s crucial to consult your healthcare provider. Maintaining proper thyroid function is vital for both you and your baby. Your healthcare team will monitor thyroid levels and adjust the medication dosage to ensure a healthy pregnancy.

Our Guarantee

At, we assure you the most affordable price to buy Thyrox tablets online from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Thyrox 50 mcg at a substantial cost, call us at 1-888-779-2193 toll-free.


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