Brinzolamide / Brimonidine tartrate

Simbrinza

Simbrinza is a combination eye drop medication used to decrease the intraocular pressure in people with open-angle glaucoma & ocular hypertension. It contains brinzolamide and brimonidine, which work together to reduce fluid production and enhance fluid drainage in the eye. Simbrinza offers the advantage of targeting two different mechanisms to effectively manage eye pressure, making it a versatile option for those who require a multi-faceted treatment approach.

Product Overview

Simbrinza combines two active ingredients, brinzolamide and brimonidine tartrate, to effectively manage elevated intraocular pressure in individuals diagnosed with ocular hypertension or open-angle glaucoma. Brinzolamide, a carbonic anhydrase inhibitor, reduces fluid production in the eye, while brimonidine, an alpha-2 adrenergic receptor agonist, decreases fluid production and increases fluid outflow. 

This dual-action formula provides a comprehensive approach to controlling eye pressure, which can prevent further optic nerve damage and potential vision loss associated with these conditions. Simbrinza is administered through a convenient dropper bottle, allowing for precise dosing typically three times a day. 

This regimen helps maintain consistent pressure levels throughout the day, offering relief and protection to patients. Despite its effectiveness, users should be aware of potential side effects like eye irritation, dry mouth, and drowsiness. Overall, this medication provides a critical solution for managing chronic eye conditions with minimal systemic impact and you can buy Simbrinza online from Canada easily.

What Is Simbrinza Used For?

Simbrinza helps in treating increased eye pressure in patients with the following conditions:

• Open-Angle Glaucoma
• Ocular Hypertension

What Are the Benefits of Simbrinza? 

• Effectively reduces intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
• Combines two different medications (brinzolamide and brimonidine) to provide more comprehensive treatment than single-agent therapies.
• Works by decreasing fluid production in the eye and improving fluid drainage, which helps lower eye pressure.
• Can be used as an alternative treatment option for patients who do not respond well to other glaucoma medications.
• Helps prevent potential vision loss associated with persistently high eye pressure.
• Provides a convenient once-daily dosing regimen, improving patient compliance.
• May be suitable for patients who require multiple mechanisms of action to control their eye pressure.
• Offers a targeted approach to managing glaucoma by addressing both fluid production and drainage.
• Generally well-tolerated with a relatively low risk of systemic side effects.
• Can be used in patients who have not achieved adequate pressure control with other topical eye medications.

What Are the Side Effects of Simbrinza? 

Common Simbrinza side effects may include:

• Eye discomfort
• Feeling of something in the eye
• Dry eyes
• Drowsiness
• Eye redness
• Headache
• Blurred vision
• Unusual taste
• Eye irritation
• Dry mouth

[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]

What Are the Forms & Strengths of Simbrinza?

• Form: Simbrinza comes as a liquid solution in a dropper bottle, which is specifically designed for easy application into the eye.
• Strength: Simbrinza is available in one concentration, combining 1% brinzolamide and 0.2% brimonidine tartrate.

What Is the Typical Dosage of Simbrinza?

Dosage of Simbrinza for Increased Eye Pressure

• • Recommended Dosage for Adults and Children Over 2 Years: Apply one drop into each affected eye three times a day.

• Application Instructions:

• • • Avoid touching the dropper tip to any surface or the eye to prevent infections.
    • If using other eye drops, discuss with your doctor for safety and compatibility.
    • If combining with other drops, wait at least 5 minutes between applications.

• Pediatric Dosage:

• • Under 2 Years: Simbrinza is not recommended for children under 2 years old.
  • 2 Years and Older: The dosage is the same as for adults.

How to Take Simbrinza?

• Preparation: Shake the bottle well before each use to mix the medication properly.
• Hygiene: Wash your hands with soap and water to clean them before handling the dropper.
• Application: Tilt your head back, pull down your lower eyelid to form a pocket, and place one drop from the dropper into the pocket without touching your eye.
• After Application: Close your eyes for 2-3 minutes without blinking. Press gently on the inner corner of your eye to keep the drop from draining away.

What to Do When You Miss a Dose of Simbrinza?

• If you miss a dose and it’s close to the time for your next dose, skip the missed one. Do not double the dose.
• Set alarms or reminders to help you remember to take your medication on schedule.

[Note: Do not take two doses of Simbrinza at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]

What Happens When You Overdose on Simbrinza?

• If you use more than the prescribed amount of Simbrinza, seek medical help right away. Overdosing can lead to serious side effects.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Simbrinza Work?

Simbrinza lowers eye pressure by reducing fluid production and enhancing drainage in the eye. It contains brinzolamide (decreases fluid production) and brimonidine tartrate (also reduces fluid and improves drainage), effectively managing eye conditions like glaucoma.

What Are the Important Safety Precautions of Simbrinza?

• Consultation Required: Always consult your doctor if you experience any unusual symptoms or adverse effects.
• Kidney Disease: Not recommended for patients with severe kidney issues due to poor understanding of its effects.
• Heart Disease: May lower blood pressure; not advised for those with heart disease or heart failure without consulting a doctor.
• Sudden Angle-Closure Glaucoma: Ineffective for this condition; seek immediate medical attention if experiencing severe eye pain or blurry vision.
• Liver Disease: Use with caution; discuss any liver conditions with your doctor as monitoring may be required.
• Allergic Reactions: Avoid if allergic to Simbrinza or sulfa; consult a doctor if unsure about allergies.
• Corneal Health: May increase the risk of corneal swelling; monitor corneal health closely if corneal cell count is low.
• Vascular Diseases: Use cautiously if you have vascular problems, especially orthostatic hypotension.
• Pregnancy and Breastfeeding: The safety of Simbrinza during pregnancy and breastfeeding is not established; use only if the potential benefits outweigh the risks.
• Birth Control: Discuss birth control needs to ensure protection against pregnancy while using Simbrinza.

How Do You Store Simbrinza?

• Storage Conditions: Keep at room temperature or refrigerate between 36°F and 77°F (2°C to 25°C). Avoid moisture-rich areas like bathrooms.
• Disposal: Dispose of unused or expired Simbrinza safely to prevent accidental use and environmental damage.

What Drugs Interact with Simbrinza?

Drugs that can interact with Simbrinza are mentioned below:

• Oral Carbonic Anhydrase Inhibitors:
  • Acetazolamide
  • Methazolamide
  • Keveyis (dichlorphenamide)
• Salicylates
  • Aspirin
  • Doan’s (magnesium salicylate)
  • Pepto Bismol (bismuth subsalicylate)
• Digoxin
• Central Nervous System Depressants:
  • Barbiturates
  • Opiates
  • Xanax (alprazolam)
• Monoamine Oxidase Inhibitors:
  • Emsam (selegiline)
  • Nardil (phenelzine)
  • Parnate (tranylcypromine)
• Blood Pressure Drugs:
  • Toprol XL (metoprolol)
  • Norvasc (amlodipine)
  • Lopressor (metoprolol)
  • Cozaar (losartan)
• Certain Antidepressants:
  • Silenor (doxepin)
  • Imipramine
  • Pamelor (nortriptyline)
  • Amitriptyline

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

What Is the Best Alternative to Simbrinza?

• Alphagan-P (brimonidine)
• Lumigan (bimatoprost)
• Timoptic (timolol)
• Travatan-Z (travoprost)
• Cosopt (dorzolamide/timolol)
• Azopt (brinzolamide)
• Xalatan (latanoprost)
• Carteolol (carteolol)
• Timoptic-XE (timolol)
• Combigan (brimonidine/timolol)
• Trusopt (dorzolamide)
• Timoptic in Ocudose (timolol)
• Betoptic (betaxolol)

[Note: Your healthcare provider will choose which Simbrinza alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]

Simbrinza Cost & Coupons

Simbrinza is essential for managing eye pressure, but it doesn’t have to be expensive. Arctic Meds provides Simbrinza at much lower prices when you buy online from Canada. Benefit from our competitive rates that help U.S. residents save on healthcare. Use the Simbrinza coupon code ARCTIC10 to get an extra 10% off on your first order. Plus, save up to $200 on your medication expenses by joining our referral program.

Frequently Asked Questions

How long should you use Simbrinza?

Continue using Simbrinza daily for as long as your doctor has prescribed. If you have questions about the duration of stopping the medication, consult your doctor or pharmacist for guidance.

Do you have to shake Simbrinza?

Yes, always shake the bottle well before each dose to mix the medication properly. If using other eye drops, apply them at least 5 minutes apart from Simbrinza to ensure effective absorption. Remove contact lenses before using the drops.

Does Simbrinza make you tired?

Simbrinza may cause side effects such as eye discomfort, itching, redness, dry eyes, blurred vision temporarily, a dry or unusual taste in your mouth, dizziness, drowsiness, tiredness, and headaches.

How often do you use Simbrinza eye drops?

For controlling increased eye pressure due to open-angle glaucoma or ocular hypertension, the usual dosage is one drop in the affected eye(s) three times a day.

Who cannot take Simbrinza?

Simbrinza is not suitable for individuals with lung diseases like asthma or those with unstable heart failure, which can cause symptoms such as shortness of breath, lightheadedness, night coughs, tiredness, and chest pain.

How much does Simbrinza lower eye pressure?

In clinical studies, Simbrinza has proven effective in lowering intraocular pressure. After 3 months of treatment, Simbrinza typically reduces eye pressure by approximately 8.5 mmHg, similar to the reduction seen with other combination treatments.

Our Guarantee

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