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Rosuvastatin Calcium


Rosuvastatin is a lipid-lowering medication approved by the FDA to manage high cholesterol levels. It effectively reduces LDL (bad) cholesterol, raises HDL (good) cholesterol, and lowers triglyceride levels. Rosuvastatin works by inhibiting an enzyme involved in cholesterol production in the liver. It helps prevent plaque buildup in arteries, reducing the risk of heart disease and stroke. Available in various strengths, Rosuvastatin is generally well-tolerated and can be taken with or without food.

Product Overview

Rosuvastatin is a highly effective statin medication used for managing various forms of high cholesterol and lipid disorders. It effectively lowers harmful LDL (low-density lipoprotein) cholesterol levels, often referred to as “bad” cholesterol. Additionally, Rosuvastatin can help raise beneficial HDL (high-density lipoprotein) cholesterol levels, known as “good” cholesterol. 

It also reduces triglyceride levels, another type of fat found in the blood. By lowering LDL cholesterol and regulating lipid levels, Rosuvastatin helps prevent plaque buildup in the arteries, reducing the risk of cardiovascular events such as heart attacks and strokes. Apart from its lipid-lowering effects, Rosuvastatin may provide additional cardiovascular benefits. 

It is generally well-tolerated, with a low risk of serious side effects when used as directed. Rosuvastatin is available in various dosage strengths, allowing for individualized treatment based on patient needs. It can be conveniently taken with or without food.

Uses of Rosuvastatin

  • Lowering high triglyceride levels
  • Lowering high “bad” cholesterol

Benefits of Rosuvastatin

  • Effectively lowers high levels of low-density lipoprotein (LDL) cholesterol, often called “bad” cholesterol.
  • Can help raise levels of high-density lipoprotein (HDL) cholesterol, known as “good” cholesterol.
  • Reduces triglyceride levels, another type of fat found in the blood.
  • Helps prevent plaque buildup in the arteries, reducing the risk of heart disease and stroke.
  • May provide additional cardiovascular benefits beyond lowering cholesterol levels.
  • Generally well-tolerated, with a low risk of serious side effects when used as directed.
  • Available in a wide range of dosage strengths, allowing for individualized treatment.
  • Can be taken with or without food for added convenience.
  • May be more potent and effective than some other statins at lowering LDL cholesterol levels.
  • Provides an effective long-term treatment option for managing high cholesterol and reducing cardiovascular risk.
  • Can be used alone or in combination with other cholesterol-lowering medications if needed.

Side Effects of Rosuvastatin

Common side effects of Rosuvastatin may include:

  • Fatigue
  • Constipation
  • Increased blood sugar levels (hyperglycemia)
  • Muscle pain or weakness (myalgia)
  • Nasopharyngitis (inflammation of the nose and throat)
  • Nausea
  • Abdominal pain or discomfort
  • Headache
  • Insomnia
  • Dizziness

[Note: This list is not exhaustive, if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Rosuvastatin Dosage

Forms & Strengths

It is available as oral tablets in the following strengths:

  • Rosuvastatin 5 mg tablets
  • Rosuvastatin 10 mg tablets
  • Rosuvastatin 20 mg tablets
  • Rosuvastatin 40 mg tablets

Recommended Dosages

For Adults with
  • Hyperlipidemia (High Cholesterol):
      • Initial Dose: 10 mg to 20 mg once daily
      • Maintenance Dose: 5 mg to 40 mg once daily
      • Maximum Dose: 40 mg (High dose reserved for those not reaching LDL-C goal with 20 mg)
  • Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL):
      • Initial Dose: 10 mg to 20 mg once daily
      • Maintenance Dose: 5 mg to 40 mg once daily
      • Maximum Dose: 40 mg (High dose reserved for those not reaching LDL-C goal with 20 mg)
  • Hypertriglyceridemia (High Triglycerides):
    • Initial Dose: 10 mg to 20 mg once daily
    • Maintenance Dose: 5 mg to 40 mg once daily
    • Maximum Dose: 40 mg (High dose reserved for those not reaching LDL-C goal with 20 mg)
For Children with
  • Heterozygous Familial Hypercholesterolemia (Inherited High Cholesterol):
      • Ages 8-10 years: 5 mg to 10 mg once daily
      • Ages 10-17 years: 5 mg to 20 mg once daily
  • Homozygous Familial Hypercholesterolemia (Inherited High Cholesterol):
    • Recommended Dose: 20 mg once daily

How to Take Rosuvastatin?

  • You should take the tablets exactly as prescribed by your doctor.
  • Take one tablet daily by swallowing it whole with water.
  • You can take the tablets anytime, with or without food.
  • Do not change or stop the dose without consulting your doctor.
  • Your doctor may check your cholesterol levels before and during Rosuvastatin treatment and adjust the dose accordingly.
  • Before starting Rosuvastatin, your doctor may recommend that you follow a cholesterol-lowering diet. You should continue following this diet while taking the medication.
  • Wait at least two hours after taking Rosuvastatin tablets before taking an antacid containing aluminum or magnesium hydroxide.

Missed Dose 

Take the missed dose when you remember, as long as it’s not too close to your next scheduled dose. 

[Note: Do not simultaneously take two doses of Rosuvastatin to compensate for a missed dose. This can increase your risk of experiencing side effects.]


Symptoms of an overdose may include severe muscle pain, weakness, or tenderness, as well as liver problems. Do not attempt to treat an overdose on your own; seek medical attention immediately.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Rosuvastatin Work?

Rosuvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol production in the liver. Rosuvastatin Calcium blocks this enzyme and reduces the liver’s ability to produce cholesterol, leading to lower LDL (bad) cholesterol levels in the bloodstream. It can also modestly increase HDL (good) cholesterol levels. By lowering LDL cholesterol levels, Rosuvastatin helps reduce the risk of cardiovascular issues like heart attacks and strokes in individuals with high cholesterol levels.

Important Safety Precautions

Before taking this medication, take these precautions:

  • Inform your healthcare professional about any existing medical conditions, such as liver or kidney problems, allergies, or a history of muscle issues.
  • Report any unusual muscle pain, weakness, or tenderness to your doctor promptly. They may need to adjust your Rosuvastatin dose.
  • Avoid eating grapes or drinking grape juice while taking Rosuvastatin.
  • Limit alcohol consumption and discuss your alcohol intake with your doctor.
  • If you are of Asian descent, be aware that you may have higher levels of Rosuvastatin in your bloodstream, and follow your doctor’s recommendations closely.
  • If you become pregnant while taking Rosuvastatin, contact your doctor immediately.
  • Do not breastfeed while taking Rosuvastatin without consulting your doctor.
  • Attend all scheduled lab tests to monitor your liver function and overall health.


  • Store Rosuvastatin tablets at room temperature between 20°C to 25°C (68°F to 77°F).
  • Keep the medication in its original container with the lid tightly closed.
  • Protect from moisture and light.
  • Keep Rosuvastatin out of reach of children and pets.
  • Do not store Rosuvastatin in the bathroom or kitchen, as these areas have high moisture levels.

Rosuvastatin Interactions

Rosuvastatin may interact with some medications; here are some mentioned below:

  • Antifungal medications, such as Itraconazole and Ketoconazole
  • Daptomycin
  • Niacin
  • Grapefruit juice
  • Cyclosporine
  • Contraceptives containing ethinyl estradiol and norethindrone
  • Warfarin
  • Rifampin
  • Calcium channel blockers (Diltiazem and Amlodipine)
  • Ezetimibe
  • Heart medications, such as Amiodarone and Verapamil
  • Digoxin
  • Fibrates, such as Gemfibrozil and Fenofibrate
  • Mifepristone
  • Lomitapide
  • HIV protease inhibitors, such as Ritonavir and Atazanavir
  • Colchicine
  • Antibiotics, such as Clarithromycin and Erythromycin

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

Rosuvastatin Alternatives

  • Zocor (simvastatin)
  • Mevacor (lovastatin)
  • Pravachol (pravastatin sodium)
  • Lescol (fluvastatin)
  • Altoprev (lovastatin)
  • Livalo (pitavastatin)
  • Lipitor (atorvastatin)

[Note: Your healthcare provider will choose which Rosuvastatin alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

What is the most serious side effect of Rosuvastatin? 

Although rare, the most serious side effects of Rosuvastatin are unexplained muscle pain, tenderness, weakness, or cramps. These symptoms could indicate muscle breakdown and potential kidney damage. If you experience any of these symptoms, stop taking Rosuvastatin immediately and seek medical attention.

Why does Rosuvastatin have to be taken at night? 

Rosuvastatin can be taken at any time of the day. However, healthcare providers often recommend taking it before bedtime. This timing is preferred because Rosuvastatin interferes with the process of cholesterol production in the liver, which primarily occurs at night.

What foods should be avoided when taking Rosuvastatin? 

Unlike some other statins, you can eat and drink normally while taking Rosuvastatin. Consuming grapefruit juice while on Rosuvastatin is safe, which is not the case with certain other cholesterol-lowering medications.

Can I stop taking Rosuvastatin once my cholesterol levels are normal? 

It is important to continue taking Rosuvastatin as prescribed by your doctor, even after achieving normal cholesterol levels. Consistent use helps maintain optimal cholesterol control and reduces the risk of heart disease. Stopping the medication abruptly could lead to a rebound effect, causing your cholesterol levels to rise again. Always follow your healthcare provider’s advice for the best long-term outcomes.

Our Guarantee

At Arctic Meds, we guarantee that you will find the most competitive prices for purchasing Rosuvastatin through our platform. As the best Canadian online pharmacy, we are committed to delivering only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Rosuvastatin online from Canada at a low price contact us.


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