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Ranitidine Hydrochloride

Ranitidine

Ranitidine 150 mg tablets are commonly used to manage and prevent the recurrence of ulcers in the stomach and intestines. Additionally, it addresses issues such as erosive esophagitis, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome by reducing stomach acid production. This helps alleviate symptoms like persistent cough, stomach pain, heartburn, and difficulty swallowing. Belonging to the H2 blockers drug class, Ranitidine, available in 150 mg of strength, can also be purchased over the counter for the prevention and treatment of indigestion. When using Ranitidine for self-treatment, it is crucial to follow the manufacturer’s package instructions closely and know when to seek advice from a doctor or pharmacist. So, if you want to buy Ranitidine 150 mg tablets, then you can contact the best Canadian online pharmacy.

Product Overview

Ranitidine 150 mg Tablet is used to decrease stomach acid production, helping to alleviate and prevent conditions such as heartburn, indigestion, and stomach ulcers. It’s also used to manage reflux disease and certain less common medical conditions. Additionally, it is often prescribed instead of using painkillers. The dosage and duration of treatment with Ranitidine 150 mg Tablet should be strictly followed as your doctor prescribes. The required amount and frequency depend on the condition being treated. 

Generally, symptoms like indigestion and heartburn are relieved within a few hours, and the medication may only be necessary for a short period when symptoms occur. A longer duration may be required to prevent ulcers and other conditions. Consistent use is essential for preventing future issues. Lifestyle modifications like eating more frequent meals & avoiding spicy or fatty foods can also enhance symptom management. While most individuals experience no side effects, the most common ones include headaches, constipation, drowsiness, and diarrhea. 

These side effects are generally very mild & resolve either upon discontinuation of the medication or as your body adjusts to it. Before starting Ranitidine, inform your doctor of any kidney or liver issues you may have, as these could influence the medication’s dosage or suitability. It’s also important to discuss any other medications you are taking, as they can interact with Ranitidine. This medication is generally safe during pregnancy and breastfeeding when prescribed by a doctor. However, avoid alcohol as it can increase stomach acid and worsen symptoms.

Uses of Ranitidine 

  • Management of Gastroesophageal Reflux Disease (Acid Reflux)
  • Management of Peptic Ulcer Disease

How to Use Ranitidine?

Dosage

Form: Ranitidine can be taken orally and available in the form of tablets.

Strength: 150 mg

Recommended Dosage for Different Patients

For People with Duodenal Ulcer: 

  • Take 150 mg orally twice a day or 300 mg once a day after the evening meal or at bedtime.
  • Maintenance Dose: Take 150 mg orally once a day at bedtime.
  • Duration of Therapy: 8 weeks for treatment; up to 1 year for maintenance.

For People with Dyspepsia (Over-the-counter formulations):

  • Symptom Relief: Take 75 to 150 mg orally with a glass of water.
  • Symptom Prevention: Take 75 to 150 mg orally with water, 30-60 minutes prior to a meal.
  • Maximum Dose: 2 tablets per day.
  • Duration of Therapy: Up to 14 days.

For People with Erosive Esophagitis:

  • Treatment Dose: Take 150 mg orally 4 times a day.
  • Maintenance Dose: Take 150 mg orally 2 times a day.
  • Duration of Therapy: Up to 48 weeks for maintenance.

For People with Zollinger-Ellison Syndrome:

  • Initial Dose: Take 150 mg orally 2 times a day.
  • Usual Dose (IV): 2 to 4 mg/kg, divided and given every 6-8 hours or as a continuous infusion.
  • Maximum Dose: 50 mg per dose for patients aged 16 years and older.

[Note: Keep in mind that these suggestions can differ based on individual circumstances. Consult with your doctor, who will adjust your dosage to suit your specific needs.]

How to Take It?

  • Follow the prescribed dosage of Ranitidine and duration as directed by your healthcare provider.
  • Swallow the tablet whole; do not chew, crush, or break it.
  • Ranitidine 150 mg Tablet can be taken with or without food.
  • Do not take more than 2 tablets in one day (24 hours) unless directed by your doctor.
  • For best results, take the medication at the same time each day.
  • Do not take it for more than 2 weeks continuously without talking with your doctor or healthcare provider. Also, do not discontinue the medication without consulting them.

[Note: Your doctor will decide the right amount for you based on your condition, following guidelines and studies on the drug. They’ll adjust it as needed over time.]

How Does Ranitidine Work?

After you eat, a hormone called gastrin is produced in the stomach lining. It triggers the release of histamine, which then attaches to histamine H2 receptors. This leads to the stomach releasing gastric acid. Ranitidine 150 mg works by attaching to these histamine (H2) receptors, which are on gastric parietal cells. This blocks histamine from attaching to the receptors, reducing gastric acid production. This can relieve symptoms related to excess stomach acid within about an hour after taking it. The effects can last from 4 to 10 hours, giving quick and effective relief.

Important Safety Information

Side Effects

Common side effects of Ranitidine include: 

  • Headache
  • Nausea or Vomiting
  • Constipation
  • Fast or Slow Heart Rate
  • Shortness of Breath

Serious side effects of Ranitidine include: 

  • Dizziness
  • Diarrhea
  • Stomach Pain
  • Mental Confusion
  • Easy Bruising or Bleeding
  • Dark Urine 
  • Jaundice

[Note: Remember, this list may not cover all possible side effects. Always consult with your healthcare giver for medical advice about side effects.]

Warnings

  • Using Ranitidine 150 mg may increase your risk of developing pneumonia. This risk is more common in older adults who are immunocompromised or have taken higher doses for a long time. 
  • If you are allergic to Ranitidine or any of the ingredients in the medication, do not use it. Allergic reactions to Ranitidine can be serious, including rash, itching, severe dizziness, swelling, or trouble breathing. If you experience any of these symptoms, seek immediate medical attention.
  • While heartburn is a common sign of acid reflux, it’s important to recognize the difference between heartburn and a heart attack. The symptoms of a heart attack might include chest pain or discomfort, pain that spreads to the arm or shoulder, nausea, sweating, and a general feeling of illness. 
  • Patients with kidney disease should use Ranitidine 150 mg Tablet with caution. The kidneys play an important role in filtering and eliminating the drug from the body. In patients with reduced kidney function, Ranitidine may accumulate, leading to heightened side effects. Dose adjustments may be necessary to prevent complications. Always consult your doctor for guidance and monitoring if you have kidney issues.
  • Ranitidine 150 mg Tablet should be used cautiously in patients with liver disease. The liver is helpful in metabolizing drugs, and impaired liver function can affect the elimination of Ranitidine, potentially leading to toxicity. Patients with liver issues may require adjusted doses or alternative treatments. It is important to consult a healthcare provider who can monitor liver function and make any necessary adjustments to your treatment plan.

Precautions

Alcohol: If you are using Ranitidine 150 mg Tablet, consuming alcohol can be dangerous. Alcohol can boost the acid production in your stomach, worsening conditions such as acid reflux or ulcers that the medication is often prescribed to manage. Additionally, combining alcohol with Ranitidine can amplify side effects such as dizziness, drowsiness, and difficulty concentrating. If you drink alcohol, discuss with your healthcare provider the potential risks and how to mitigate them effectively.

Pregnancy: Ranitidine 150 mg Tablet is generally considered safe during pregnancy when prescribed by a doctor. Animal studies have shown minimal to no adverse effects on the developing fetus, while human studies are limited but reassuring. The decision to use Ranitidine during pregnancy should be based on the medication’s benefits outweighing potential risks. Always consult with your doctor to ensure the safest treatment options during your pregnancy.

Breastfeeding: According to limited human data, 150 mg of ranitidine tablet is likely safe to use while breastfeeding. This medication may pass into breast milk in small amounts & is unlikely to harm a nursing baby. However, as with all medications, it is crucial to consult your healthcare provider before starting Ranitidine to discuss any possible risks and ensure it is the best option for both you and your baby.

Driving: Ranitidine 150 mg Tablet does not generally impair your ability to drive or operate machinery. Unlike some other medications, Ranitidine does not usually cause drowsiness, dizziness, or blurred vision. However, individual reactions to medication can vary. If you experience any side effects that could affect your concentration or motor skills, avoid driving or operating heavy machinery and consult your healthcare provider.

Missed Dose

  • If you forget to take a dose of Ranitidine 150 mg Tablet, take it as soon as you remember.
  • If it’s almost time for your next dose, skip the missed dose.
  • Continue with your daily dosing schedule.
  • Do not take a double Ranitidine dose to make up for a missed one.
  • Try to take your medication at the same time each day for consistency.
  • Keep track of your medication intake to ensure all doses are present.

[Note: If you have missed a dose of your medication and are still determining when to take the next one, immediately consult your doctor or pharmacist.]

Overdose 

Overdose symptoms may include lack of coordination, sensations of lightheadedness, or fainting. These signs require prompt attention to mitigate potential complications. If you suspect an overdose or experience any of these symptoms after taking Ranitidine 150 mg, do not hesitate to seek assistance immediately or contact the Poison Helpline at 1-800-222-1222. It is important to act quickly in such situations to ensure your safety and well-being. 

[Note: If you have taken more than the recommended Ranitidine 150 mg dose, get medical help immediately or call the Poison Help line at 1-800-222-1222.]

Storage

  • Store this medication at room temperature (25℃), away from light and moisture. 
  • You can also avoid storing this medication in the bathroom. 
  • You can keep this medication out of reach of children and pets. 
  • To dispose of this medication, do not pour it into a drain or flush it down the toilet unless instructed to do so. 
  • You can properly discard this medication product when it is expired or no longer needed. 

[Note: Discuss with your healthcare professional the proper disposal of unused medicine and any questions you may have regarding its storage.]

Ranitidine 150 mg Interactions

6 Disease Interactions: Ranitidine 150 mg may interact with various medical conditions, including GI bleeding, porphyria, hemodialysis, liver disease, Phenylketonuria, and renal dysfunction.

Alcohol/Food Interaction: Ranitidine 150 mg may interact with alcohol, potentially affecting its absorption or metabolism. It’s advisable to limit alcohol consumption while taking this medication. Ranitidine 150 mg may also interact with certain foods. 

12 Major Drugs Interaction: Ranitidine 150 mg may interact with 12 major drugs, including atazanavir, dasatinib, gefitinib, infigratinib, loperamide, neratinib, nirogacestat, pazopanib, rilpivirine, selpercatinib, siponimod, and sotorasib.

66 Moderate Drugs Interaction: Ranitidine 150 mg may also interact with 66 moderate drugs such as acalabrutinib, dacomitinib, flibanserin, ketoconazole, tenofovir alafenamide, thalidomide, theophylline, and more.

 61 Minor Drugs Interaction: Ranitidine 150 mg may also interact with minor drugs like

acetaminophen, alendronate, aluminum carbonate, aluminum hydroxide, atracurium, axitinib, calcium carbonate, cyclosporine, diclofenac, didanosine, dihydroxyaluminum sodium carbonate, doxacurium, duloxetine, enoxacin, succinylcholine, sulindac, tolmetin, triamterene, tubocurarine, vandetanib, vecuronium, vismodegib, and more.

[Note: This isn’t a complete list, and there could be other drugs that interact with Ranitidine 150 mg. Make sure to tell your doctor about any prescription, over-the-counter medicines, and herbal products you’re taking.]

Ranitidine Alternatives

[Note: Your doctor will choose what’s best for you. Don’t use any of these alternative medications without consulting your healthcare provider. Taking them by yourself may cause serious side effects.] 

Frequently Asked Questions

What is Ranitidine 150 mg used for?

Ranitidine is a medication primarily used to manage and heal ulcers in the stomach & intestines, as well as to prevent their recurrence once recovery has occurred. Additionally, it addresses a range of stomach and esophageal conditions, including erosive esophagitis and more. By reducing stomach acid production, Ranitidine helps alleviate pain and facilitates the healing process of the digestive tract.

Is it safe to take Ranitidine?

Ranitidine, once a common treatment option, has been discontinued in the United States. Information in this leaflet is maintained solely for historical reference. It’s important to note that the use of Ranitidine was associated with an elevated risk of pneumonia. This document does not endorse the use of Ranitidine due to its withdrawal from the market and potential health risks.

What is APO Ranitidine 150 mg used for?

This medication is designed to decrease the production of stomach acid. It is commonly prescribed to prevent  ulcers, manage gastroesophageal reflux disease (GERD)—a condition characterized by heartburn and the backward flow of stomach acid into the esophagus—or alleviate symptoms of heartburn and indigestion. This treatment helps maintain a healthier balance of stomach acids, promoting better digestive health and reducing discomfort.

What should I watch for while using this medication?

You should consider the following while using this medication:

  • Inform your doctor or pharmacist if your medical condition does not improve or worsen. It may take several days of taking this medication before your symptoms improve. Complete the full course of tablets prescribed, even if you start feeling better. 
  • Avoid smoking cigarettes or consuming alcohol, as they can irritate your stomach and delay ulcer healing. They can also exacerbate acid reflux or heartburn.
  • If you experience black, tarry stools or vomit that resembles coffee grounds, contact your doctor or healthcare professional immediately, as this may indicate a bleeding ulcer. 
  • This medication may lead to a decrease in vitamin B12 levels. Ensure you maintain an adequate intake of vitamin B12 while taking this medication. Discuss your diet and vitamin supplements with your healthcare professional.

Is Ranitidine 150 mg the same as Zantac?

Yes! Ranitidine 150 mg, commonly known by its brand name Zantac, is available over the counter (OTC) and as a prescription medication. Marketed by Sanofi, Zantac falls under the class of drugs called Histamine-2 blockers. Over-the-counter Ranitidine is frequently used to alleviate and prevent heartburn. Zantac’s availability in both OTC and prescription forms offers flexibility to consumers seeking relief from heartburn symptoms. 

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