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Antipsychotic

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Pimozide is an antipsychotic medication primarily used to treat Tourette syndrome when other treatments are ineffective. It works by blocking dopamine receptors, helping to reduce tics and other symptoms. Pimozide is available in tablet form and should be used under close medical supervision due to potential side effects like drowsiness, weight gain, heart rhythm changes, and increased prolactin levels. Regular monitoring is essential, especially for heart rhythm abnormalities, and dosage adjustments may be necessary based on individual patient responses.

Product Overview

Pimozide is a typical antipsychotic medication primarily prescribed for managing severe cases of Tourette syndrome, especially when standard treatments fail. It works by blocking dopamine receptors in the brain, which helps reduce the frequency and severity of involuntary tics and vocalizations associated with Tourette’s syndrome. Available in tablet form, Pimozide comes in strengths of 1 mg and 2 mg and requires careful titration to minimize side effects.

Common side effects include drowsiness, dry mouth, constipation, dizziness, and heart rhythm abnormalities like QT prolongation. Due to the risk of cardiac arrhythmias, regular ECG monitoring is recommended, especially during dose adjustments. Pimozide is contraindicated in patients with certain pre-existing heart conditions or those taking medications that prolong the QT interval. Patients with liver or kidney impairments may require dosage adjustments, and close monitoring is essential.

Pimozide should not be stopped suddenly and requires medical guidance throughout treatment. Depending on patient response and tolerance, alternative medications may be considered, and regular follow-ups are advised to ensure safety and efficacy.

What Are the Uses of Pimozide?

  • Treat Tourette syndrome in patients when other medications have not been effective.

What Are the Benefits of Pimozide?

  • Reduces the frequency and severity of tics and vocalizations in patients with Tourette’s syndrome.
  • It can be used off-label for severe, treatment-resistant obsessive-compulsive disorder (OCD).
  • Alleviates distressing symptoms, helping patients regain control over daily activities.
  • Provides sustained relief with appropriate dosing under medical supervision.
  • Blocks dopamine receptors, helping manage symptoms related to excessive dopamine activity in the brain.

What Are the Side Effects of Pimozide?

Common Pimozide side effects may include:

  • Restlessness
  • Blurred vision
  • Weight gain
  • Dizziness
  • Dry mouth
  • Changes in heart rhythm (QT prolongation)
  • Constipation
  • Increased prolactin levels
  • Tremors or muscle stiffness
  • Drowsiness or sedation

[Note: This list is not exhaustive, if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Pimozide Dosage

What Are the Forms & Strengths of Pimozide?

It comes in the form of tablets and is available in two strengths:

  • Pimozide 1mg tablet
  • Pimozide 2mg tablet

What Are the Recommended Dosages of Pimozide?

For Adults with Tourette’s Syndrome
  • Initial Dose: 1 to 2 mg per day, divided into two doses.
  • Dose Increase: Gradually increase the dose by 1 mg every other day.
  • Maximum Dose: Do not exceed 10 mg per day.
For Children (12 years and older) with Tourette’s Syndrome
  • Initial Dose: 0.05 mg per kg of body weight per day, divided into two doses.
  • Dose Increase: Gradually increase by 0.05 mg per kg every other day.
  • Maximum Dose: Do not exceed 10 mg per day.
For Geriatric Patients
  • Initial Dose: Start with the lower end of the dose range.
  • Dose Increase: Gradually adjust based on response and tolerance.
  • Monitoring: Close monitoring for side effects and effectiveness is essential.
For Patients with Liver or Kidney Impairment
  • Dose Adjustment: Lower doses may be needed.
  • Monitoring: Regular liver and kidney function tests are recommended.

How to Take Pimozide?

  • Never stop taking Pimozide suddenly without talking to your doctor, as this could make your symptoms worse.
  • Regularly visit your doctor for check-ups to monitor your progress and possibly adjust your dosage.
  • Swallow the Pimozide tablet whole with a glass of water. 
  • Store Pimozide at room temperature, away from moisture, heat, and light, and keep it out of reach of children and pets.
  • Do not crush, chew, or break the tablet.
  • Be cautious when driving or doing anything that requires alertness, as Pimozide can cause drowsiness and dizziness.
  • Avoid alcohol and grapefruit or grapefruit juice, as these can increase side effects.

What to Do When You Miss a Dose of Pimozide? 

  • Take the missed dose as soon as you remember unless it’s nearly time for your next dose.
  • If it’s almost time for your next dose, skip the missed one and continue your regular dosing schedule.

[Note: Do not take two doses of Pimozide simultaneously to compensate for a missed dose. This can increase your risk of experiencing side effects.]

What Happens When You Overdose on Pimozide?

An overdose of Pimozide is a medical emergency and needs immediate attention.

Symptoms of an overdose may include extreme drowsiness, confusion, slurred speech, muscle stiffness or spasms, tremors, slow or irregular heartbeat, fainting, seizures, and, in severe cases, coma or death.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Pimozide Work?

Pimozide is an antipsychotic medication used mainly to treat symptoms of Tourette’s syndrome, which includes uncontrollable tics and vocal outbursts. It belongs to a class of drugs known as typical antipsychotics and works by blocking dopamine receptors, specifically D2 receptors in the brain. Dopamine is a neurotransmitter that affects mood, behavior, and movement. By reducing dopamine activity, Pimozide helps to lessen the frequency and severity of tics and other symptoms of Tourette’s syndrome. It may also be used off-label for severe, hard-to-treat cases of obsessive-compulsive disorder (OCD) and other psychiatric conditions.

Important Safety Precautions

  • Pimozide can cause QT prolongation and serious cardiac arrhythmias, including Torsades de Pointes, and sudden death, especially at higher doses. Regular ECG monitoring is recommended.
  • Inform your doctor if you have allergies to pimozide or similar medications.
  • Avoid certain antibiotics, antifungals, HIV medications, SSRIs, and heart rhythm drugs. Consult your doctor about potential interactions.
  • Discontinue amphetamines and similar medications before starting Pimozide, as they may cause tics.
  • Notify your doctor if you have QT syndrome, irregular heartbeat, low potassium/magnesium levels, or other medical conditions.
  • Inform your doctor if you are pregnant or breastfeeding.
  • Pimozide may cause dizziness or drowsiness; avoid driving or operating machinery.
  • Consult your doctor about alcohol use, as it may worsen side effects.

How to Store Pimozide? 

  • Store Pimozide at room temperature, ideally between 68°F to 77°F.
  • Keep the medication in a dry place. Avoid storing it in bathrooms where it’s often humid.
  • Protect the medication from light by storing it in its original container or a container that resists light.
  • Ensure the container is tightly closed when not in use.
  • Always store the medication in its original packaging or container.
  • Keep Pimozide out of reach of children and pets to ensure their safety.
  • Follow specific storage instructions if provided by your pharmacist or doctor.

What Drugs Interact with Pimozide?

  • Antibiotics: (such as erythromycin or clarithromycin)
  • Calcium channel blockers (such as verapamil or diltiazem)
  • Antidepressants: Certain SSRIs (such as fluoxetine or sertraline)
  • Grapefruit juice
  • Antifungal medications: (such as ketoconazole, itraconazole)
  • Other antipsychotics
  • Antiarrhythmics: (such as amiodarone, quinidine)
  • Antiviral drugs: (such as ritonavir)

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

What Are the Pimozide Alternatives?

  • Xenazine (tetrabenazine)
  • Geodon (ziprasidone)
  • Prolixin (fluphenazine)
  • Risperdal (risperidone)
  • Intuniv, Tenex (guanfacine)
  • Abilify (aripiprazole)
  • Thorazine (chlorpromazine)
  • Seroquel (quetiapine)
  • Zyprexa (olanzapine)
  • Invega (paliperidone)
  • Clozaril (clozapine)
  • Haldol (haloperidol)
  • Catapres (clonidine)
  • Risperdal (risperidone)
  • Haldol (haloperidol)

[Note: Your healthcare provider will choose which Pimozide alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]

Pimozide Cost & Coupons

For many patients in the U.S., Pimozide can be costly, mainly if insurance doesn’t fully cover it. To make treatment more affordable, consider to buy Pimozide online from Canada through Arctic Meds. You can apply a Pimozide coupon code to reduce expenses and make it easier to access this vital medication. Arctic Meds helps provide Pimozide at a very low price, offering a more affordable option for those managing Tourette syndrome or other conditions.

Frequently Asked Questions

How long does it take for Pimozide to work?

Pimozide typically starts showing effects within a few weeks. Most doctors evaluate its impact after about a month of consistent use. Be patient and follow your healthcare provider’s guidance during this period.

Can Pimozide cause tardive dyskinesia?

Yes, Pimozide, like other antipsychotic medications, can lead to tardive dyskinesia (TD), a condition that causes uncontrollable, repetitive facial movements. If you notice any unusual movements, contact your healthcare provider right away.

Can Pimozide be used during pregnancy?

Pimozide use during the third trimester of pregnancy can be risky for your baby. It may lead to movement issues or withdrawal symptoms after birth. If you’re pregnant or planning to become pregnant, discuss safer treatment options with your healthcare provider.

Can Pimozide cause weight gain?

Weight gain is not a common side effect of Pimozide, though some individuals may experience weight changes. In clinical trials, some people gained weight while others lost weight. Keep track of any changes and inform your doctor if needed.

Our Guarantee

At Arctic Meds, we guarantee that you will find the most competitive prices for purchasing Pimozide through our platform. As the best Canadian online pharmacy, we are committed to delivering only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Pimozide online from Canada at a low price contact us.

IMPORTANT NOTE: The information available on the Arctic Meds website is intended to enhance awareness about healthcare products and medical conditions. It is for informational purposes only. Always consult a qualified healthcare professional before using any prescription or non-prescription medication. Our platform offers access to a broad selection of products that are sourced from various countries including Canada. We operate with both a licensed partnered pharmacy located in Canada along with reputable dispensing pharmacies located globally. All affiliated fulfillment centers are approved by the regulatory bodies of their respective countries.

SHIPPING

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(Shipping times may vary based on time of year)

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Refrigerated items $29.99
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