Nitazoxanide
Buy Nitazoxanide Online
Nitazoxanide is an FDA-approved antiparasitic medication primarily used to treat diarrhea caused by protozoa and also treats certain worm infections. It works by inhibiting the enzyme and disrupting the energy production process in parasites, leading to their elimination. It is available as a tablet and liquid suspension with 500 mg and 100 mg/ml strengths, respectively. For safe and efficient use of Nitazoxanide, you should take it exactly as your doctor prescribes.
Product Overview
Nitazoxanide is an antiparasitic medication primarily used to treat diarrhea caused by protozoal infections and certain worm infestations. The active ingredient, Nitazoxanide, works by inhibiting the enzyme pyruvate: ferredoxin oxidoreductase, disrupting the energy production process in parasites, leading to their elimination.
Available in tablet form with a strength of 500 mg and as an oral suspension at 100 mg/ml, Nitazoxanide should be taken as your doctor prescribes, typically every 12 hours with food for three days. It is indicated for use in adults and children aged 12 and older, with a healthcare professional providing specific dosage instructions for younger children.
Common side effects of Nitazoxanide include abdominal pain, nausea, vomiting, and discolored urine. If any severe side effects occur, consult your doctor immediately. Store Nitazoxanide in a cool, dry place away from direct sunlight. In case of a missed dose, take it as soon as possible, but do not double up on doses. Dispose of unused medication responsibly to avoid harm to others.
Uses of Nitazoxanide
It is used to treat:
- Diarrhea
- Worm infections
Benefits of Nitazoxanide
It effectively treats certain parasitic infections of the intestines.
Side Effects of Nitazoxanide
Common Nitazoxanide side effects may include:
- Abdominal pain
- Nausea
- Vomiting
- Diarrhea
- Headache
- Discolored urine
[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Nitazoxanide Dosage
Forms & Strengths
It is available in the following forms and strengths:
Form: Tablet
Strength: 500 mg
Form: Oral suspension
Strength: 100 mg/ml
Recommended Dosages
For Treatment of Diarrhea Caused by Protozoa
Tablets
- Adults and children 12 years or older: 500mg to be taken orally with food every twelve hours for three days.
- Children up to 11 years of age: Nitazoxanide tablets are not recommended for patients of this age group.
Oral Suspension
- Adults & children 12 years or older: 25 ml every 12 hours, taken with food, for three days.
- Children 4-11 years of age: 10 ml every 12 hours, taken with food, orally for three days.
- Children 1-3 years of age: 5 ml taken every 12 hours with food for three days.
- Children under a year: Your doctor should determine the usage and dosage.
How to Take Nitazoxanide?
- Before using Nitazoxanide, you should carefully read and follow the directions given in the patient information leaflet and medication guide provided by your pharmacist or healthcare provider. If you have any queries or concerns or if you do not understand any part of the leaflet, you should consult a medical professional.
- Take this medication exactly as your doctor has prescribed, usually every twelve hours for three days. Do not use more or less of it, in large quantities or for longer than prescribed, as it can cause undesirable side effects.
- If you are taking an oral suspension form of Nitazoxanide, shake its bottle well before using. Carefully measure the medication dosage using a special measuring device or spoon.
- For pediatric patients, the medication dosage is based on their weight. Children less than 11 years of age should take the oral liquid form of the medication.
- Antibiotics such as Nitazoxanide work best when the amount of medication is kept at a consistent level. You should take Nitazoxanide at evenly spaced intervals.
- You should continue to take this medication for the entire duration prescribed, even if you feel well. Discontinuing the medication too early may result in a return of the infection.
- Tell your doctor if your condition does get better or if it worsens.
Missed Dose
- If you have missed a dose of Nitazoxanide, you should take it as soon as you remember.
- However, if your next dose is almost here, you can skip the missed one and carry on taking your medication as usual.
- Do not take double or extra doses of the same medication to make up for a missed one.
- You can set a reminder on your phone to prevent missing any more doses. Medication reminders work best for this purpose.
[Note: Do not take two doses of Nitazoxanide at the same time to compensate for a missed dose. This can increase your risk of experiencing unwanted side effects.]
Overdose
If you suspect someone has overdosed on Nitazoxanide, you should seek prompt medical assistance, especially if someone is experiencing severe side effects such as difficulty breathing and passing out. You can call your doctor, 911, or poison control helpline. You can also head to the nearest emergency room.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Nitazoxanide Work?
Nitazoxanide functions by inhibiting the enzyme pyruvate: ferredoxin oxidoreductase, which is vital for the anaerobic energy metabolism of some bacteria and parasites. By blocking this enzyme, Nitazoxanide disrupts the energy production process, leading to the death of the parasites and bacteria. This mechanism makes it effective against various protozoa, helminths, and some anaerobic bacteria. It’s commonly used to treat infections like giardiasis and cryptosporidiosis.
Important Safety Precautions
- Before using this medication, tell your doctor or medical provider if you have an allergy to Nitazoxanide, any other medications or food items, etc. This medication can contain inactive ingredients, which may cause severe allergic reactions or other problems. You can ask your pharmacist or medical provider for the complete list of ingredients present in the medication.
- Before using this medication, share your complete medical history with your medical provider, especially if you have a compromised immune system due to an HIV infection, problems with the immune system, liver disease, or kidney failure.
- The oral suspension form of this medication has sugar. You should use it cautiously if you have sugar.
- Nitazoxanide should only be used during pregnancy when it is clearly needed. Discuss the risks & benefits of using this medication during pregnancy with your doctor.
- It is not known if Nitazoxanide passes into breast milk and causes harm to the nursing baby. Consult your medical giver before breastfeeding an infant while using this medication.
- Before using this medication, tell your doctor about all the medications you are currently taking or plan to take, including all prescription, non-prescription, over-the-counter, herbal, and vitamin supplements.
Storage
- Keep Nitazoxanide in its original container, tightly closed to protect it from direct sunlight, excess heat, and moisture. Do not keep it in the bathroom and other high-humidity areas.
- You should keep all medications, including Nitazoxanide, in a safe place out of the sight and reach of children and pets.
- Do not keep medications that are outdated or no longer needed. Make sure you dispose of them properly.
- Unless specifically instructed to do so, do not dispose of them in the household garbage bin, down the toilet, or down the drain.
- You should dispose of medications that have passed their expiration date or are no longer needed in such a way that prevents children, animals, and other people from consuming them.
- The best way to get rid of unwanted medications is to participate in the medicine take-back program.
- Consult your pharmacist, waste disposal company, or healthcare provider for more information on how to get rid of unwanted medications.
Nitazoxanide Interactions
Certain medications may interact with Nitazoxanide and affect how it may work. Some of the significant interactions of Nitazoxanide are as follows:
- Lisocabtagene maraleucel
- Phenytoin
- Brexucabtagene autoleucel
- Valproic acid
- Tisagenlecleucel
- Ciltacabtagene autoleucel
- Idecabtagene vicleucel
- Axicabtagene ciloleucel
- Baricitinib
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Nitazoxanide Alternatives
- Albendazole
- Mebendazole
- Ivermectin
- Vermox
- Pyrantel
- Albenza
[Note: Your healthcare provider will choose which Nitazoxanide alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
Can we use Nitazoxanide to treat viral infections?
Yes, Nitazoxanide has been studied for its antiviral properties and is used off-label to treat certain viral infections, including norovirus and rotavirus.
How does Nitazoxanide interact with other medications?
Nitazoxanide may interact with medications metabolized by the liver’s cytochrome P450 enzymes, potentially altering their effectiveness or increasing side effects.
What is the role of Nitazoxanide in treating chronic diarrhea?
Nitazoxanide effectively treats chronic diarrhea caused by protozoal infections, particularly in immunocompromised patients, by disrupting the parasites’ energy metabolism.
Is Nitazoxanide effective against drug-resistant pathogens?
Nitazoxanide has shown effectiveness against some drug-resistant pathogens, making it a potential alternative treatment when conventional therapies fail.
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