Moclobemide
Buy Moclobemide Online
Moclobemide is an antidepressant medication that is primarily used to treat depression. It functions as a reversible inhibitor of monoamine oxidase A (MAO-A), which increases serotonin, dopamine, and noradrenaline levels in the brain, aiding in symptom reduction. Moclobemide is available in tablet form, with strengths of 150 and 300 mg, and is to be taken orally after meals. Consult an expert medical provider for personalized guidance and recommendations regarding medication dosage, usage, and more.
Product Overview
Moclobemide is an antidepressant medication containing the active ingredient moclobemide, primarily used to treat depression. It functions as a reversible inhibitor of monoamine oxidase A (MAO-A), which increases the levels of mood-enhancing neurotransmitters like serotonin, dopamine, and noradrenaline in the brain, aiding in symptom reduction.
Moclobemide is available in tablet form in strengths of 150 mg and 300 mg. It is taken orally after meals. The initial recommended dosage for adults is 150 mg twice daily, with a maximum medication dosage of 600mg. It is not recommended for children unless prescribed by a doctor.
Common side effects include difficulty sleeping, dizziness, and stomach upset. Patients should follow their doctor’s instructions and not discontinue use abruptly. Missed doses should be taken as soon as remembered, but not doubled. Moclobemide should be stored in its original container at a controlled room temperature, away from heat and moisture, and out of reach of children and pets.
Uses of Moclobemide
It is used to treat:
- Depression
Benefits of Moclobemide
- It has demonstrated effectiveness and efficacy in managing both endogenous and non-endogenous depression.
- Compared to other antidepressants, Moclobemide has a relatively fast onset of action.
Side Effects of Moclobemide
Common Moclobemide side effects may include:
- Difficulty sleeping
- Dizziness
- Stomach upset, including nausea, vomiting, constipation, or diarrhea
- Dry mouth
- Headache
- Nervousness
- Tingling or numbness in the hands or feet
[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Moclobemide Dosage
Forms & Strengths
It is available in tablet form and comes in the following strengths:
- 150mg
- 300mg
Recommended Dosages
For Treating Depression
- Adults: The initial recommended dosage is 150 mg twice daily. Your doctor may adjust your dosage if required. However, the maximum dosage should not exceed 600 mg.
- Children: Your doctor will determine the usage and dosage.
How to Take Moclobemide?
- Before using Moclobemide, you should carefully read and follow the instructions for use given in the patient information leaflet and medication guide provided by your pharmacist or medical giver. You should consult your physician if you have any queries or concerns regarding the medication use or do not understand any part of this leaflet.
- You should use Moclobemide tablets exactly as prescribed by your doctor. Do not use more or less of it, in large quantities, or more than prescribed, as it can cause undesirable side effects.
- Take Moclobemide after a meal orally, by mouth, with a glass of water.
- Before using this medication, ask your doctor if you need to make dietary changes while receiving treatment with Moclobemide.
- Do not consume alcohol in large amounts while receiving treatment with Moclobemide.
- It may take several weeks to notice the full effects of this medication.
- You should visit your doctor on a regular basis to check the progress of the medication, especially during the initial months of treatment.
- To get the most benefit from your medication, you should maintain consistency in dosage and try to take it around the same time every day.
- Do not abruptly discontinue using this medication without consulting your doctor.
- Inform your doctor if your condition does not get better or if it worsens.
- Do not share your medications with others, even if they have the same condition as you do.
Missed Dose
- If you have missed a dose of Moclobemide, take it as soon as remembered.
- However, if the time to take your next dose is approaching, you may omit the missed dose and continue taking your medication according to your dosing schedule.
- If you are still deciding when to take your next dose, consult your physician or medical provider.
- You can set a reminder on your phone to prevent missing your doses. Medication reminders work best for this purpose.
[Note: Do not take two doses of Moclobemide at the same time to compensate for a missed dose. This can increase your risk of experiencing unwanted side effects.]
Overdose
Overdose of Moclobemide combined with a serotonergic agent can cause severe serotonin toxicity. If you suspect a Moclobemide overdose, you should immediately seek medical help. You can call your doctor, 911, or poison control helpline. You can also head to the nearest emergency room.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Moclobemide Work?
Moclobemide is primarily used to treat depression and social anxiety. Unlike older irreversible MAOIs, Moclobemide doesn’t cause a severe rise in blood pressure when combined with amines like tyramine-containing foods or pressor amine drugs. It increases levels of mood-enhancing neurotransmitters such as serotonin, dopamine, and noradrenaline in the brain, leading to symptom reduction in depression. Additionally, Moclobemide lacks anticholinergic effects and is advantageous for elderly patients & those with cardiovascular disease.
Important Safety Precautions
- When used in combination with certain beverages and medications, certain MAOIs, including Moclobemide, can cause severe reactions such as hypertensive crisis. To prevent this, you should not consume excessive amounts of alcohol and do not take any medication without consulting your doctor.
- Call your doctor immediately if you experience severe headache, pounding heartbeat, or irregular or slow heartbeat.
- You should not discontinue taking Moclobemide without consulting your doctor. If you plan to discontinue taking this medication, inform your doctor. They will help you gradually taper off the medication.
- You may experience lightheadedness, dizziness, or fainting, especially when you get up after sitting or lying for an extended period. To prevent this, you should get up slowly.
- Moclobemide may affect your vision or cause dizziness or drowsiness. You should not drive, operate heavy machinery, or engage in tasks that require clear vision or mental alertness unless you can do it safely.
- If you plan to have surgery, including a dental procedure, tell your dentist, doctor, or surgeon that you are using this medication. Also, tell them about all your medications, including all prescription, non-prescription, over-the-counter drugs, and herbal and vitamin supplements.
- You should continue to remain cautious for at least 14 days after discontinuing using this medication related to your diet and medications since these things may continue to interact with Moclobemide.
- You should not use Moclobemide if you have an allergy to it or any of the ingredients present in the medication.
Storage
- Store Moclobemide in its original container to protect it from direct sunlight, moisture, and excess heat.
- You should keep it at a controlled room temperature, typically between 15-30°C or 59-86°F.
- Keep the medication in a cool and dry place. Avoid keeping it in the bathroom, near the sink, or in other humid areas.
- Store it in a secure place, like a high container, out of sight and reach of children and pets.
- Check the expiration date of the medications regularly and discard any expired or outdated medication properly.
- You should dispose of unwanted medications in such a way that prevents children, animals, and other people from consuming them. Consult your medical provider, local waste disposal company, or pharmacist to learn more about the proper ways to eliminate unwanted medications.
Moclobemide Interactions
- Amoxapine
- Apraclonidine
- Benzphetamine
- Brimonidine
- Bupropion
- Desipramine
- Lofepramine
- Maprotiline
- Nortriptyline
- Opipramol
- Ozanimod
- Phendimetrazine
- Phenmetrazine
- Phentermine
- Reserpine
- Safinamide
- Trazodone
- Trimipramine
- Tryptophan
- Venlafaxine
- Viloxazine
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Moclobemide Alternatives
- Agomelatine
- Mirtazapine
- Trazodone
- Vortioxetine
[Note: Your healthcare provider will choose which Moclobemide alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
Is Moclobemide a good antidepressant?
Yes, Moclobemide is considered an effective antidepressant, particularly for treating depression, with fewer side effects compared to other antidepressants. Its reversible inhibition of MAO-A leads to a quicker onset of action, making it a preferred choice for many patients.
Does Moclobemide inhibit MAO-B?
No, Moclobemide primarily inhibits MAO-A, not MAO-B. This selective inhibition makes Moclobemide effective in increasing serotonin, dopamine, and noradrenaline levels while avoiding the severe side effects associated with non-selective MAO inhibitors.
Is Moclobemide a sedative?
Moclobemide is not classified as a sedative. It is an antidepressant that works by increasing mood-enhancing neurotransmitters in the brain. Unlike sedatives, Moclobemide does not induce drowsiness or sedation but may cause dizziness in some individuals.
What to avoid with Moclobemide?
When taking Moclobemide, avoid excessive alcohol consumption and certain foods rich in tyramine, as they may cause hypertensive reactions. Also, avoid using other medications, especially MAOIs and certain antidepressants, without consulting your doctor.
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