SAVE $20 OFF First Orders with Coupon Code: POLARBEARN20

Buy Mestinon (Pyridostigmine) Online from Canada

Mestinon Pyridostigmine Bromide



Mestinon is an FDA-approved medication for neuromuscular disorders like myasthenia gravis. It boosts muscle strength by increasing acetylcholine levels. It offers flexible dosing and is available in various forms, including tablets and syrup. Side effects may include tingling, rash, vomiting, and diarrhea. Take as directed and inform your doctor of all medications. Proper storage is important for potency. Mestinon enhances muscle function, improving the quality of life for those with neuromuscular conditions.

Product Overview 

Mestinon (pyridostigmine) is a cholinesterase inhibitor used primarily to manage and treat symptoms of myasthenia gravis, a neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. By preventing the breakdown of acetylcholine, Mestinon enhances communication between nerves and muscles, thereby improving muscle strength and control. This action helps to alleviate symptoms such as muscle weakness, enhancing the overall quality of life for those affected.

Available in various forms, including immediate-release tablets (60 mg), controlled-release tablets (180 mg), oral syrup (60 mg per 5 mL), and an injectable solution (5 mg per mL), Mestinon offers flexibility in dosing to meet individual patient needs. For myasthenia gravis, the typical initial oral dose ranges from 30 to 60 mg every 3 to 4 hours, with adjustments made based on symptomatic relief.

While effective, Mestinon may cause side effects like nausea, diarrhea, increased salivation, and sweating. Patients should consult their healthcare provider for tailored advice and to ensure safe use, particularly those with conditions like asthma, heart disease, or gastrointestinal ulcers. Routine monitoring and consultation with a healthcare provider are crucial to optimize treatment with Mestinon.

Uses of Mestinon

  • Myasthenia Gravis

Benefits of Mestinon 

  • Improves muscle strength and control
  • Helps manage symptoms of myasthenia gravis
  • Increases levels of acetylcholine, a neurotransmitter involved in muscle contraction
  • Enhances communication between nerves and muscles
  • It can improve the quality of life for individuals with certain neuromuscular disorders

Side Effects of Mestinon 

Common side effects of Mestinon may include:

  • Warmth or tingly feeling
  • Rash or itching
  • Pale skin
  • Vomiting
  • Increased sweating or cold sweat
  • Decreased pupil size
  • Diarrhea
  • Watery eyes
  • Increased saliva/mucus
  • Upset stomach
  • Increased urination
  • Abdominal cramps
  • Nausea


[Note: This list is not exhaustive, if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Mestinon Dosage

Forms & Strengths

Here are the different forms and strengths of Mestinon:

  • Injectable Solution: 5 mg per mL
  • Controlled-Release Tablet: 180 mg
  • Immediate-Release Tablet: 60 mg
  • Oral Syrup: 60 mg per 5 mL (240 mL bottle)

Recommended Dosages

For Myasthenia Gravis:
  • Initial dose: 30 to 60 mg orally, every 3 to 4 hours as needed for symptomatic relief.
  • Maintenance dose: 60 to 120 mg orally, every 3 to 6 hours as needed.
For Orthostatic Hypotension:
  • Initial dose: 30 mg orally, 2 to 3 times daily.
  • Maintenance dose: Adjusted based on patient response, typically 30 to 60 mg orally, 2 to 3 times daily.
For Reversal of Nondepolarizing Neuromuscular Blockade:
  • The anesthesiologist determines dose and frequency based on the patient’s condition and response to treatment.

How to Take Mestinon? 

  • Take Mestinon precisely as your doctor advised.
  • Typically, it’s taken orally with or without a meal.
  • Swallow the tablet whole with a full glass of water.
  • Avoid crushing, chewing, or breaking the medication unless instructed otherwise.
  • Do not take the extra dosage of this medicine to make up for a missed dose.
  • If you are not sure, consult your doctor or pharmacist for clarification.

Missed Dose 

If you miss a dose of Mestinon, take it as soon as you remember. However, if it’s almost time for your next scheduled dosage, skip the missed dose of Mestinon and continue with your regular dosing schedule. Do not double up on Mestinon doses to make up for a missed one. If you have any concerns or questions, consult your healthcare provider.


[Note: Do not simultaneously take two doses of Mestinon to compensate for a missed dose. This can heighten your risk of experiencing side effects.]


An overdose of Mestinon can lead to serious side effects such as excessive salivation, sweating, nausea, vomiting, diarrhea, muscle weakness, difficulty breathing, seizures, and possibly coma. If you suspect an overdose, seek immediate medical attention or contact a poison control center right away.


[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Mestinon Work?

Mestinon, also known as pyridostigmine, prevents the degradation of acetylcholine, a neurotransmitter responsible for playing a vital role in muscle contraction. By blocking the enzyme acetylcholinesterase, Mestinon increases the levels of acetylcholine, enhancing communication between nerves and muscles. This mechanism helps improve muscle strength and control, particularly in conditions like myasthenia gravis.

Important Safety Precautions

  • Before starting Mestinon, inform your doctor about all medications, supplements & herbal remedies, as they may interact with certain drugs.
  • Be cautious if you have asthma, epilepsy, heart disease, gastrointestinal ulcers, or urinary tract obstruction, as Mestinon may worsen these conditions.
  • Practice caution when driving or operating machinery, as Mestinon may cause dizziness, blurred vision, or muscle weakness.
  • Avoid alcohol while taking Mestinon, as it may exacerbate side effects.
  • Keep Mestinon out of reach of children and pets, as overdose can be dangerous.
  • If you become pregnant or plan to breastfeed while taking Mestinon, consult your doctor for guidance on its safety.
  • Attend routine check-ups with your doctor to monitor your response to Mestinon and adjust the dosage if necessary.
  • In case of any unusual symptoms or reactions, promptly consult your healthcare provider for guidance.


  • Keep Mestinon tablets at room temperature, away from moisture and heat.
  • Keep the medication stored in its original container with the lid tightly closed.
  • Keep Mestinon out of reach of children and pets.
  • Do not store Mestinon in the bathroom or close to the kitchen sink, as moisture can affect its efficacy.
  • If you have unused or expired medication, discard it according to local regulations or consult your pharmacist.

Mestinon Interactions 

  • Anticholinergic medications: Combining Mestinon with drugs that have anticholinergic effects, such as certain antidepressants, antihistamines, and medicines for overactive bladder, can reduce its effectiveness.
  • Corticosteroids: Concurrent use of corticosteroids with Mestinon may increase the risk of muscle weakness or other adverse effects.
  • Nondepolarizing neuromuscular blocking agents: Mestinon may potentiate the effects of nondepolarizing neuromuscular blocking agents used during surgery.
  • Beta-blockers: Beta-blockers may enhance the effects of Mestinon, leading to increased muscle weakness or other side effects.
  • Cholinergic agonists: Combining Mestinon with other cholinergic agonists may result in additive effects, elevating the risk of side effects.
  • Drugs that affect gastrointestinal motility: Certain medications, such as certain antidiarrheals or medicines for gastrointestinal disorders, may interact with Mestinon and alter its absorption or effectiveness.


[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

Mestinon Alternatives 

  • Prostigmin (neostigmine)
  • Mytelase (ambenonium)
  • Tensilon (edrophonium)
  • Regonol (pyridostigmine bromide)
  • Exelon (rivastigmine)
  • Aricept (donepezil)
  • Razadyne, Reminyl (galantamine)


[Note: Your healthcare provider will choose which Mestinon alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

How soon does Mestinon typically begin to take effect?

Mestinon usually starts working within 15 to 30 minutes. Discuss your treatment routine with your healthcare provider to optimize its effectiveness in managing muscle weakness throughout the day.

What is the duration of action for Mestinon?

The immediate-release tablet and oral solution of Mestinon typically provide effects lasting 3 to 4 hours, necessitating multiple daily doses. The extended-release formulation may offer a slightly longer duration of action. Consult your healthcare provider to determine the optimal dosing schedule for your needs.

Is it safe to consume alcohol while taking Mestinon?

While alcohol doesn’t typically interfere with the effectiveness of Mestinon, it’s advisable to restrict alcohol intake due to potential exacerbation of specific side effects like nausea, vomiting, and stomach upset. Consult your healthcare professional regarding your alcohol consumption habits and whether it’s advisable to limit or avoid alcohol while on Mestinon.

Is Mestinon classified as a steroid medication?

No, Mestinon is not a steroid. It belongs to a class of medications known as cholinesterase inhibitors. Pyridostigmine works by increasing acetylcholine levels in the body to alleviate muscle weakness associated with conditions like myasthenia gravis. On the other hand, Steroids may also be prescribed for myasthenia gravis to reduce inflammation by suppressing immune system activity. In some cases, both pyridostigmine and steroids may be required to manage the condition effectively.

Our Guarantee

At Arctic Meds, we guarantee you will find the most competitive prices for purchasing Mestinon through our platform. As the best Canadian online pharmacy, we are dedicated to delivering only top-quality medications. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Mestinon online from Canada at a low price, contact us.


All orders are shipped via XPRESS POST arriving between 3-5 business days.
(Shipping times may vary based on time of year)

Shipping prices:
Refrigerated items $29.99
Non-refrigerated items $19.99

Questions? Watch our shipping video here!

Shipping costs will be added at checkout.



5.0 out of 5 stars (based on 360 reviews)
Very good1%

Thank you very much for your help

August 11, 2022

The customer service is outstanding. I appreciate it.


Thanks so much!

August 10, 2022

You all have been amazing and I’m so glad I found you

I love doing business with our Canadian


So Easy to order

July 27, 2022

It is very easy to order with them. The prices are great and the shipping is so quick. Highly Recommend them!


Best Service EVER!

July 26, 2022

Anytime I call and need help, they are always there and help me in every way possible. I love working with them. Best service ever!


My first order with a Canadian pharmacy

July 15, 2022

First time ordering from this pharmacy. The entire process was so easy and the questions I did have the customer service representative was very helpful and knew what he was talking about. I felt so good having found them

Scroll to Top