Mesalamine
Buy Mesalamine DR Online
Mesalamine is an FDA-approved anti-inflammatory medication used to treat inflammatory bowel diseases (IBD), such as Crohn’s disease & ulcerative colitis. It functions by reducing inflammation in the colon, which helps manage and improve symptoms of IBD. It is available in different forms, with strengths ranging from 800 mg to 1.2 grams per tablet. You can buy Mesalamine DR online from Canada from the convenience of your home.
Product Overview
Mesalamine DR, an effective treatment for inflammatory bowel diseases like ulcerative colitis and Crohn’s disease, contains the active ingredient mesalamine. This medication targets inflammation directly in the colon, reducing symptoms such as stomach pain and diarrhea.
It comes in various forms, such as oral tablets and capsules (400 mg, 800 mg, 1200 mg), rectal suppositories (1000 mg), and rectal enemas (4 g/60 ml). It should be taken as prescribed, suitable for adults, and swallowed whole with plenty of fluids. Common side effects of Mesalamine may include abdominal pain, diarrhea, and headache. Important precautions include avoiding use if allergic to mesalamine or salicylates and monitoring for symptoms of acute intolerance syndrome.
If a dose is missed, take it as soon as possible unless it’s near the time for the next dose. In case of a mesalamine overdose, seek immediate medical help. Store Mesalamine at room temperature away from light, moisture & heat, and keep out of sight and reach of children and pets. Follow your healthcare provider’s instructions for safe and effective use.
Uses of Mesalamine DR
It is used to treat:
- Ulcerative colitis
- Crohn’s disease
Benefits of Mesalamine DR
- It is effective in providing relief from symptoms of ulcerative colitis, which include stomach pain, diarrhea, and gut inflammation.
- It can also be used to maintain remission and prevent flare-ups in adults with ulcerative colitis.
Side Effects of Mesalamine DR
Common Mesalamine DR side effects may include:
- Abdominal pain
- Constipation
- Diarrhea
- Headache
- Dizziness
- Flu-like symptoms
- Rash
- Nausea
- Gas (flatulence)
[Note: This list is not exhaustive; if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
Mesalamine DR Dosage
Forms & Strengths
It is available in the following forms and strengths:
Form: Oral Tablets
Strength: 800 mg, 1200 mg
Form: Oral Capsules
Strength: 400 mg
Form: Rectal suppositories
Strength: 1000 mg
Form: Rectal enemas
Strength: 4 g/60 ml
Recommended Dosages
For Ulcerative Colitis:
Oral tablets/capsules: 1.6-4.8 g/day in divided doses
Rectal suppositories: 1 g once daily
Rectal enemas: 4 g once daily
For Maintenance of Remission:
Oral: 1.6-2.4 g/day
Rectal: 1 g suppository 2-3 times per week
How to Take Mesalamine DR?
- Before taking Mesalamine DR and each time you get a refill, you should carefully read and follow the directions in the medication guide and patient information leaflet provided by your druggist or healthcare provider.
- Use Mesalamine DR exactly as your doctor prescribed. You should take the capsule form with or without food and the tablet form with meals.
- Swallow this medication whole. You should not crush, chew, or break it.
- Drink plenty of fluids while receiving treatment with Mesalamine DR unless instructed otherwise.
- The medication dosage is based on the condition being treated and the response to treatment.
- To get the most out of your medicine, you should maintain consistency in dosage & take it around the same time every day.
- Tell your doctor if your condition does not get better or if it worsens.
Missed Dose
- If you have missed a dose of Mesalamine DR, you should take it as soon as you remember.
- However, if it is almost time for your next dose, you should omit the missed dose and continue taking your medication according to your dosage schedule.
- You can set a reminder on your phone to prevent missing doses further. Medication reminders work best for this purpose.
[Note: Do not take two doses of Mesalamine DR at the same time to compensate for a missed dose. This can increase your risk of experiencing unwanted side effects.]
Overdose
If you suspect an overdose of Mesalamine DR, you should seek immediate medical assistance. Mesalamine overdose symptoms may include abdominal pain, headache, dizziness, seizures, nausea, and confusion. You can call your doctor, 911, or poison control helpline.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Mesalamine DR Work?
Mesalamine DR (delayed-release) works by targeting inflammation in the colon. The medication’s delayed-release coating allows it to pass through the stomach and small intestine intact. Once it reaches the colon, the drug is released, where it acts locally to reduce inflammation by obstructing the production of inflammatory mediators like prostaglandins and leukotrienes in the intestinal tissue.
Important Safety Precautions
- Allergies: Do not take this medication if you’re allergic to mesalamine, salicylates, aminosalicylates, or any inactive ingredients. Discontinue use and call your doctor immediately if you experience severe allergic reactions such as trouble breathing, hives, or swelling of the mouth, throat, face, or tongue.
- Kidney Issues: Renal problems have been reported with this medication. Your doctor will monitor your kidney function on a regular basis. Do not take this medication if you have pre-existing kidney conditions or are taking other drugs that may affect kidney function.
- Acute Intolerance Syndrome (AIS): This medication may cause AIS, which can mimic worsening ulcerative colitis symptoms. If your symptoms worsen, stop taking the medication and inform your doctor.
- Liver Disease: This medication may not be safe for patients with liver disease.
- Blood Disorders: Elderly patients, especially those on azathioprine or 6-mercaptopurine, may be at increased risk for blood disorders. Your doctor will monitor you for this.
- Sun Sensitivity: This medication can increase sensitivity to sunlight, particularly in those with skin conditions like eczema. Limit sun exposure, avoid tanning booths, use sunscreen, and wear protective clothing. Report any sunburn, redness, or blisters to your doctor.
- Surgical Procedures: Before surgery or dental procedures, inform your medical giver about all medications and supplements you are taking.
- Reye’s Syndrome: Children and teenagers should not take aspirin or related medications if they have the flu, chickenpox, or an undiagnosed illness, as it may lead to Reye’s syndrome.
Storage
- You should store Mesalamine DR at room temperature, away from direct sunlight, moisture, and heat.
- Keep all medications, including Mesalamine DR, in a safe place, away from the sight and reach of children and pets.
- You should not pour them into wastewater, flush it down the toilet, or throw them into the trash.
- You should dispose of unwanted medications in such a way that prevents children, animals, and others from consuming them.
- For more information on how to dispose of unwanted medications, you can consult your healthcare provider, pharmacist, or local waste disposal company.
Mesalamine DR Interactions
Certain medications may interact with Mesalamine and affect how it works or increase your risk of severe side effects.
- Ketoprofen
- Indomethacin
- Diclofenac
- Ibuprofen
- Naproxen
- Celecoxib
- Methotrexate
- Mercaptopurine
- Varicella Virus Vaccine, Live
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Mesalamine DR Alternatives
- Humira
- Stelara
- Remicade
- Entyvio
- Azathioprine
- Budesonide
[Note: Your healthcare provider will choose which Mesalamine DR alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
What are the long-term effects of using Mesalamine DR for ulcerative colitis?
Long-term use of Mesalamine DR generally maintains remission in ulcerative colitis. Patients often tolerate the drug well over extended periods. However, monitoring by a healthcare provider on a regular basis is essential to manage any potential side effects, such as kidney function impairment or increased sensitivity to sunlight.
Can Mesalamine DR be used during pregnancy?
Mesalamine DR is classified as a Category B medication for pregnancy, indicating no evidence of harm to the fetus in animal studies and insufficient human data. Pregnant women should use this medication only if clearly needed and after discussing potential risks and benefits with their healthcare provider.
How does Mesalamine DR interact with other common medications?
Mesalamine DR can interact with NSAIDs, azathioprine, mercaptopurine, and varicella virus vaccine, potentially increasing side effects. To avoid adverse interactions and ensure optimal treatment efficacy, it’s important to tell your medical giver about all medications you are taking.
Is there a recommended diet while taking Mesalamine DR for IBD?
While no specific diet is recommended for patients taking Mesalamine DR, following a balanced diet that avoids individual trigger foods can help manage IBD symptoms. Patients are often advised to maintain hydration and may benefit from consulting a dietitian to create a personalized eating plan.
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