Mesalamine
Buy Lialda Online
Lialda (mesalamine) is a delayed-release tablet used primarily to treat and manage ulcerative colitis. It reduces inflammation in the colon, helping to induce and maintain remission, alleviate symptoms like diarrhea, rectal bleeding, and abdominal pain, and improve the overall quality of life. Lialda uses MMX technology for targeted medication release and offers the convenience of once-daily dosing. It is generally well-tolerated with a favorable side effect profile, suitable for adults and children aged 5 and above. Common side effects include dizziness, nausea, and headaches. Lialda may also reduce the need for more invasive treatments.
Product Overview
Lialda, known generically as mesalamine, is a medication specifically designed for the treatment of mild to moderate ulcerative colitis, a form of inflammatory bowel disease (IBD) that affects the colon. The drug is formulated as a delayed-release tablet, which ensures that its active ingredient is released directly in the colon, the site of inflammation. This targeted release is facilitated by MMX technology, enhancing the drug’s efficacy and reducing systemic side effects.
The primary function of Lialda is to reduce inflammation, which is key to managing the symptoms of ulcerative colitis, such as diarrhea, rectal bleeding, and abdominal pain. By doing so, Lialda not only helps to induce remission in patients experiencing flare-ups but also maintains remission, preventing future episodes. Additionally, Lialda can aid in healing the intestinal lining damaged by the disease and may decrease the frequency of flare-ups.
Administered once daily, Lialda improves treatment adherence compared to medications requiring multiple daily doses. Its formulation allows minimal systemic absorption, contributing to its generally favorable side-effect profile. Common adverse effects include dizziness, headache, nausea, and abdominal pain. Lialda is indicated for use in adults and children aged 5 years and older. Regular monitoring by a healthcare provider is recommended to assess the effectiveness of the medication and to manage any potential side effects or complications.
Uses of Lialda
- Treatment of ulcerative colitis.
Benefits of Lialda
- Effectively treats mild to moderate ulcerative colitis, reducing inflammation in the colon.
- Helps induce and maintain remission in patients with ulcerative colitis.
- Uses a unique MMX technology for targeted release of medication in the colon.
- Offers once-daily dosing, improving convenience and potentially increasing medication adherence.
- May reduce the frequency of flare-ups in patients with ulcerative colitis.
- Can help heal the intestinal lining damaged by ulcerative colitis.
- Can be used for both acute treatment and long-term maintenance therapy.
- May reduce the need for more aggressive treatments or surgery in some patients.
- Can improve quality of life by managing symptoms like diarrhea, rectal bleeding, and abdominal pain.
- Available in a delayed-release tablet form, minimizing systemic absorption and potential side effects.
- Suitable for use in adults and children 5 years and older with ulcerative colitis.
Side Effects of Lialda
Common Lialda side effects may include:
- Tremor
- Fatigue or weakness
- Loss of appetite
- Skin rash
- Nervousness or anxiety
- Dizziness
- Visual disturbances (blurred vision, difficulty focusing)
- Chest pain
- Shortness of breath
- Swelling of the hands, feet, or ankles
- Headache
- Constipation
- Dry mouth
- Palpitations or irregular heartbeat
- Nausea
[Note: This list is not exhaustive, if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Lialda Dosage
Forms & Strengths
It comes in the delayed-release tablet form and has the following strengths:
- Lialda 1.2 grams (1200 mg) tablets
Recommended Dosages
Ulcerative Colitis Treatment
For Induction of Remission for Adults: Take 2.4 to 4.8 grams daily, which equates to two to four 1.2-gram tablets. It is recommended to take these tablets with food to improve digestion and absorption.
For Maintenance of Remission for Adults: The standard dosage is 2.4 grams daily, meaning two 1.2-gram tablets should be taken with food. This helps sustain the remission of symptoms.
How to Take Lialda?
- Consistent Timing: Take Lialda at the exact times each day to maintain a steady level of medication in your bloodstream.
- With or Without Food: You can take Lialda with or without food, but taking it with food might help reduce stomach upset.
- Intact Tablets: Swallow Lialda tablets whole without chewing or crushing them. They have a special coating to ensure the medication is released in the colon, and breaking the tablet can release the medicine too early.
- Hydration: Stay well-hydrated to help the medication work more effectively and to minimize potential kidney side effects.
- Regular Check-ups: Regular visits to your healthcare provider are necessary to monitor the effectiveness of Lialda and check for side effects. You might also need blood tests to monitor your kidney function and blood cell counts.
- Gradual Discontinuation: Do not stop taking Lialda suddenly, as this may worsen your symptoms. If you need to stop, your doctor will likely taper your dose gradually.
Missed Dose
If you miss a dose of Lialda, take it as soon as you remember unless it is nearly time for your next dose.
[Note: Do not simultaneously take two doses of Lialda to compensate for a missed dose. This can increase your risk of experiencing side effects.]
Overdose
An overdose of Lialda can cause severe abdominal pain, vomiting, nausea, and diarrhea and might lead to kidney issues like interstitial nephritis. If you suspect an overdose, seek immediate medical attention.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Lialda Work?
Lialda belongs to a group of drugs called aminosalicylates. The active ingredient, mesalamine, targets the colon’s lining to block substances that trigger inflammation, effectively reducing swelling, bleeding, and discomfort linked to inflammatory bowel disease (IBD). While the precise way mesalamine works is not entirely known, it is believed to suppress the production and function of inflammatory chemicals in the colon. This specific action helps keep the disease in remission and prevents episodes of symptom flare-ups.
Important Safety Precautions
- Regular Monitoring: Regular doctor visits are crucial to monitor medication effectiveness and side effects through blood and urine tests.
- Kidney Issues: Alert your doctor if you have symptoms like back or side pain, changes in urine output, bloody urine, or swelling, which could indicate kidney problems.
- Acute Intolerance Syndrome: Seek immediate medical attention for stomach pain, bloody diarrhea, fever, or rash.
- Allergic Reactions: Report any difficulty breathing, swelling, or rash immediately, as these could be signs of an allergic reaction.
- Liver Health: Inform your doctor about upper stomach pain, dark urine, or jaundice.
- Sun Sensitivity: Protect yourself from sun exposure and avoid sunlamps due to increased sensitivity.
- Drug Interactions: Do not mix mesalamine with antacids or other medications without consulting your doctor.
- Medical Information: Ensure all healthcare providers know you’re taking mesalamine, which may affect medical tests.
Storage
- Store Lialda at room temperature, ideally between 68°F to 77°F (20°C to 25°C).
- Keep the medication in a dry place. Avoid storing it in areas with high humidity, such as bathrooms.
Lialda Interactions
Several medications can interact with Lialda (mesalamine), which includes:
- Proton Pump Inhibitors (PPIs)
- Azathioprine and 6-Mercaptopurine
- Methotrexate
- Non-steroidal anti-inflammatory Drugs (NSAIDs)
- Warfarin and Other Anticoagulants
- Heparin and Heparin-like Drugs
- Antacids
- Varicella Virus Vaccine (live)
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Lialda Alternatives
- Rowasa (mesalamine) – rectal enema
- Dipentum (olsalazine)
- Pentasa (mesalamine)
- Azulfidine (sulfasalazine)
- Asacol HD (mesalamine)
- Giazo (balsalazide) – approved for male patients only
- Delzicol (mesalamine)
- Colazal (balsalazide)
- Canasa (mesalamine) – rectal suppository
- Apriso (mesalamine)
[Note: Your healthcare provider will choose which Lialda alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
How long is Lialda typically prescribed?
Lialda is generally prescribed for long-term use if it proves safe and effective for you. It starts working to reduce bowel inflammation shortly after beginning the treatment, but it may take a few weeks before you see a significant improvement in your symptoms.
Is Lialda a biological medication?
No, Lialda is not a biological medication. Biologic drugs are derived from living cells and specifically target parts of the immune system to reduce inflammation. Lialda is made from chemicals and belongs to a class of drugs known as aminosalicylates. It helps reduce inflammation in the bowel but works through a broader approach than biologics.
Is Lialda an immunosuppressant?
No, Lialda (mesalamine) is not an immunosuppressant. It is an anti-inflammatory medication used mainly to alleviate symptoms of ulcerative colitis, like diarrhea, bleeding from the rectum, and abdominal pain. It is typically one of the first treatments recommended for managing ulcerative colitis.
Is Lialda considered a blood thinner or an NSAID?
Lialda is neither a blood thinner nor an NSAID (nonsteroidal anti-inflammatory drug). It is an aminosalicylate, which reduces inflammation primarily in the colon and rectum. While its active ingredient, mesalamine, is related to aspirin (an NSAID and blood thinner), it functions differently. Although rare, Lialda can sometimes lower platelet counts, which may lead to easier bruising or bleeding, but it is not used as a blood thinner.
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