Lamictal

Buy Lamotrigine Online

Lamotrigine is an anticonvulsant & mood stabilizer used to manage bipolar disorder and epilepsy. It helps prevent mood swings and reduces seizure frequency. Available in various forms and strengths, it’s tailored to individual needs. Common side effects of this medication comprise dizziness, headache & rash. Gradual dose adjustment is critical to minimizing serious risks. Consult your healthcare provider for personalized guidance.

Product Overview 

Lamotrigine is used primarily for managing bipolar disorder and epilepsy. It effectively prevents mood swings in bipolar disorder and reduces the frequency of seizures in epilepsy, including those associated with Lennox-Gastaut syndrome. Available in various forms and strengths, including tablets, chewable tablets, and extended-release tablets, Lamotrigine is tailored to individual treatment needs. Dosage adjustments of Lamotrigine may be necessary based on individual response, and gradual dose escalation is critical to minimize the risk of severe side effects, like life-threatening skin rashes. Lamotrigine requires careful monitoring, mainly when used alongside other medications like valproic acid or carbamazepine, which may alter its effectiveness or increase side effects. Consult your healthcare specialist if you’re pregnant, breastfeeding, or taking other medications to ensure the safe and effective use of Lamotrigine.

Uses of Lamotrigine 

• Bipolar disorder
• Epilepsy
• Lennox-Gastaut syndrome

Benefits of Lamotrigine 

• It helps prevent mood swings in bipolar disorder.
• Effective in decreasing the frequency of seizures in epilepsy.

Side Effects of Lamotrigine 

Common Lamotrigine side effects may include:

• Dizziness
• Headache
• Blurred vision or double vision
• Nausea
• Vomiting
• Sleepiness or drowsiness
• Insomnia
• Tremor
• Rash
• Loss of coordination
• Dry mouth

[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Lamotrigine Dosage

Forms & Strengths

• • Tablets:
    • 25 mg
    • 100 mg
    • 150 mg
    • 200 mg

• Chewable Dispersible Tablets:

• • • 2 mg
    • 5 mg
    • 25 mg

• Orally Disintegrating Tablets (ODT):

• • • 25 mg
    • 50 mg
    • 100 mg
    • 200 mg

• Extended-Release Tablets:

• • 25 mg
  • 50 mg
  • 100 mg
  • 200 mg
  • 250 mg
  • 300 mg

Recommended Dosages

• Bipolar Disorder (Adults):
  • Start: 25 mg once daily for two weeks.
  • Maintenance: 100-200 mg daily.
• Epilepsy (Adults and Children over 12 years):
  • Start: 25 mg once daily for two weeks.
  • Maintenance: 100-400 mg daily, depending on response.
• Epilepsy (Children 2-12 years):
  • Start: 0.3 mg/kg once daily for 2 weeks.
  • Maintenance: 1-5 mg/kg daily, depending on response.
• With Valproate (Adults and Children over 12 years):
  • Start: 25 mg every other day for 2 weeks.
  • Maintenance: 100-200 mg daily.
• With Enzyme-Inducing AEDs (Adults and Children over 12 years):
  • Start: 50 mg once daily for 2 weeks.
  • Maintenance: 300-500 mg daily.

How to Take Lamotrigine? 

• Take Lamotrigine precisely as prescribed by your healthcare provider.
• Use it simultaneously each day to maintain even levels in your bloodstream.
• Lamotrigine can be taken with or without food, depending on your preference.
• Swallow the tablet whole; do not crush, chew, or break it.
• If prescribed chewable tablets, chew them thoroughly before swallowing or dissolve them in a small liquid.
• If starting Lamotrigine, increase the dose gradually as directed to minimize the risk of medication side effects, particularly the risk of a severe skin rash.
• Do not suddenly stop taking Lamotrigine without consulting your medical specialist, as this can lead to withdrawal symptoms or seizures.

Missed Dose 

If you miss a dose of Lamotrigine, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose & continue with your regular dosing schedule. Do not take two doses simultaneously to make up for the missed dose. Missing several doses in a row can increase the risk of seizures, so contact your healthcare provider if this happens.

[Note: Do not take two doses of Lamotrigine simultaneously to compensate for a missed dose. This can elevate your risk of experiencing side effects.]

Overdose

An overdose of Lamotrigine can be serious and may lead to symptoms such as severe dizziness, loss of coordination, increased seizures, blurred vision, and even life-threatening conditions like coma. If you see an overdose of Lamotrigine, seek medical attention at earliest or call your local poison control center. Do not wait for symptoms to appear, as prompt treatment is crucial.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Lamotrigine Work?

Lamotrigine functions by stabilizing electrical activity in the brain. It is an anticonvulsant and mood stabilizer that primarily affects the release of neurotransmitters, which are chemicals that transmit signals between nerve cells. Lamotrigine blocks voltage-sensitive sodium channels, reducing the release of glutamate, an excitatory neurotransmitter involved in developing seizures and mood disorders. By dampening excessive neuronal firing, Lamotrigine helps control seizures in epilepsy and stabilizes mood swings in bipolar disorder.

Important Safety Precautions 

• Be aware of potentially life-threatening skin rashes, such as Stevens-Johnson syndrome (SJS) & toxic epidermal necrolysis (TEN), and report any rash immediately.
• Start with a low dose and increase gradually as directed to reduce the risk of serious side effects.
• Do not suddenly stop taking Lamotrigine; this can increase the risk of seizures.
• Watch for signs of depression, suicidal thoughts, or mood changes, especially during the first few weeks of treatment.
• Inform your medical professional about all medications and supplements you’re taking, as Lamotrigine can interact with other drugs.
• Consult your medical professional if you are expecting a baby, planning to become pregnant, or breastfeeding.
• Attend all scheduled appointments for blood tests & check-ups to monitor your response to the medication.

Storage 

• Keep Lamotrigine at room temperature, between 20°C to 25°.
• Store Lamotrigine in its original packaging to protect it from light and moisture.
• Avoid storing Lamotrigine in humid areas like the bathroom.
• Keep the medication out of reach of children and pets to prevent accidental ingestion.
• Do not freeze the medication.
• Dispose of expired or unused Lamotrigine following local guidelines or ask your pharmacist for advice on safe disposal.

Lamotrigine Interactions

• Valproic Acid: Increases Lamotrigine levels, raising the risk of severe side effects, especially skin rashes.
• Carbamazepine: May decrease Lamotrigine levels and increase the risk of side effects such as dizziness and vision problems.
• Oral Contraceptives: Can reduce Lamotrigine levels, potentially decreasing its effectiveness; Lamotrigine may also reduce the effectiveness of contraceptives.
• Phenytoin, Phenobarbital, and Primidone: These medications can lower Lamotrigine levels, requiring dose adjustments.
• Rifampin: May decrease Lamotrigine levels, reducing its effectiveness.
• Sertraline and Other SSRIs: May increase the risk of side effects, particularly affecting mood and behavior.
• Other Antiepileptics: Interaction with other seizure medications may require dose adjustments for both drugs.

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

Lamotrigine Alternatives 

• Valproic acid (Depakene, Depakote)
• Carbamazepine (Tegretol, Carbatrol)
• Oxcarbazepine (Trileptal)
• Levetiracetam (Keppra)
• Topiramate (Topamax)
• Gabapentin (Neurontin)
• Pregabalin (Lyrica)
• Zonisamide (Zonegran)
• Phenytoin (Dilantin)
• Lacosamide (Vimpat)
• Eslicarbazepine (Aptiom)
• Clobazam (Onfi)
• Rufinamide (Banzel)

[Note: Your healthcare provider will choose which Lamotrigine alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

How long does it take to feel the full effects of Lamotrigine?

It may take several weeks to feel the full effects of Lamotrigine. You’ll need to start with a low dose to mitigate the danger of serious side effects of this medication, and your healthcare professional will gradually increase your dosage every 1 to 2 weeks until you reach a practical level. Regular follow-up with your provider is important to monitor your progress with this medication & adjust the treatment as needed.

What should I do if I develop a rash while taking Lamotrigine?

If you get a rash while taking Lamotrigine, contact your healthcare provider immediately. Rashes from this medication can become serious or even life-threatening, so early detection is crucial. Rashes typically occur within the first 2 to 8 weeks of treatment. Your risk increases if you take a higher dose than prescribed, increase your dose too quickly, or are also taking divalproex (Depakote) or valproic acid.

Can I take Lamotrigine if I’m pregnant?

If you’re pregnant or planning to become pregnant, consult your healthcare expert about the risks and benefits of taking Lamotrigine. It’s important to discuss whether alternative treatments might be more suitable. While there’s limited information on the safety of this medication during pregnancy in humans, animal studies have shown that Lamotrigine can cause serious issues, such as low birth weight, brain or bone problems, and even death in animal offspring. 

Can I take Lamotrigine if I’m breastfeeding?

If you’re breastfeeding, it’s essential to discuss with your healthcare provider the safest options for you and your baby. There may be risks associated with taking Lamotrigine (Lamictal) while breastfeeding, as the medication is known to pass into human milk. There have been reports of side effects in breastfed infants, including rash, drowsiness, poor sucking, low weight, and breathing difficulties. Your medical specialist can help you weigh the benefits and risks to determine the best action.

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