Paliperidone

Buy Invega Online

Invega (paliperidone) is an antipsychotic medication designed to treat schizophrenia and schizoaffective disorder. It effectively reduces symptoms such as hallucinations, delusions, and disorganized thinking by balancing neurotransmitters in the brain. Available in oral and injectable forms, Invega is suitable for daily use, improving mood, cognitive function, and social interactions. Following a healthcare provider’s guidance when using Invega is critical due to its potent and potential side effects.

Product Overview 

Invega (paliperidone) is an atypical antipsychotic used primarily to treat schizophrenia and schizoaffective disorder. It functions by modulating the activity of neurotransmitters in the brain, particularly dopamine and serotonin, to alleviate symptoms such as hallucinations, delusions, and disorganized thinking. This helps improve mood, thought clarity, and overall cognitive functions, enabling better social interactions and emotional stability. Available in both oral and injectable forms, Invega offers flexible dosing options, including extended-release tablets and monthly or quarterly injections, to maintain stable medication levels for continuous symptom management. Common side effects consist of weight gain, drowsiness, and gastrointestinal discomfort. Invega is crucial for maintaining mental health stability but requires careful monitoring for severe potential side effects like Neuroleptic Malignant Syndrome or Tardive Dyskinesia. It is advised to avoid alcohol and be cautious about possible drug interactions. Always consult healthcare providers for personalized dosing and before discontinuing to avoid withdrawal symptoms.

Uses of Invega

• Schizophrenia
• Schizoaffective disorder

Benefits of Invega

• Reduces symptoms of schizophrenia
• Improves thought clarity and emotional stability
• Decreases hallucinations and delusions
• Helps in managing Schizoaffective disorder
• Supports consistent mood regulation
• Aids in the overall mental functioning and social interactions

Side Effects of Invega 

Common Invega side effects may include:

• Weight gain
• Drowsiness or fatigue
• Dizziness
• Restlessness or akathisia
• Increased heart rate
• Blurred vision
• Dry mouth
• Nausea or vomiting
• Constipation
• Nasal congestion

[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Invega Dosage

Forms & Strengths

Tablets (Extended-Release Oral):

• 1.5 mg
• 3 mg
• 6 mg
• 9 mg

Injection (Sustenna, Extended-Release):

• 39 mg/mL
• 78 mg/mL
• 117 mg/mL
• 156 mg/mL
• 234 mg/mL

Injection (Trinza, Extended-Release):

• 273 mg
• 410 mg
• 546 mg
• 819 mg

Recommended Dosages

• Schizophrenia (Adults and Adolescents):

  • Initial: 6 mg once daily
  • Range: 3-12 mg/day, adjusted based on response

• Schizoaffective Disorder (Adults):

  • Initial: 6 mg once daily
  • Maintenance: Adjust dose between 3-12 mg/day as needed

• Schizophrenia (Invega Sustenna Injection):

  • Day 1: 234 mg intramuscularly
  • Day 8: 156 mg intramuscularly
  • Monthly Maintenance: 117 mg, can be adjusted between 39-234 mg based on clinical response

• Schizophrenia (Invega Trinza Injection):

  • Transition from Sustenna: Administer the same dose used for Sustenna
  • Frequency: Once every three months

How to Take Invega? 

• Take orally with or without food, usually once daily in the morning.
• Swallow the tablet whole. Do not crush, chew, or split the tablet.
• Maintain a consistent schedule to ensure even levels of medication in the body.
• Follow your healthcare provider’s instructions carefully regarding dosage and duration of treatment.
• Do not alter the dose or discontinue the medication without consulting your doctor.
• Monitor your symptoms and report any changes to your healthcare provider.

Missed Dose 

If you miss a dose of Invega, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses simultaneously to make up for a missed dose. Missing doses can affect the effectiveness of the treatment, so it’s essential to take the medication as prescribed. 

[Note: Do not take two doses of Invega simultaneously to compensate for a missed dose. This can increase your risk of experiencing side effects.]

Overdose

An overdose of Invega (paliperidone) can be severe and potentially life-threatening. Symptoms of an overdose might include severe drowsiness, fast or irregular heartbeat, fainting, and severe restlessness or agitation. In some cases, an overdose can lead to seizures, delirium, or even coma.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Invega Work?

Invega, the brand name for paliperidone, works primarily by affecting the activity of neurotransmitters in the brain, particularly dopamine and serotonin. It is classified as an atypical antipsychotic. Invega blocks or lessens the effects of dopamine and serotonin receptors, which is believed to help correct the imbalance of these chemicals that often occur in disorders like schizophrenia and schizoaffective disorder. By modulating these neurotransmitters, Invega helps to reduce symptoms such as hallucinations, delusions, and disorganized thinking and can also help improve mood and cognition.

Important Safety Precautions

• Monitor for Neuroleptic Malignant Syndrome (NMS): Be vigilant for symptoms such as fever, muscle rigidity, altered mental status, or autonomic instability.
• Risk of Tardive Dyskinesia: Be aware of the potential for involuntary, repetitive body movements, particularly of the face.
• Orthostatic Hypotension: Caution patients about the potential for dizziness or fainting when rising from a sitting or lying position.
• Hyperglycemia and Diabetes: Monitor glucose levels in patients with diabetes or those at risk for diabetes.
• Weight Gain: Monitor weight regularly due to the potential for significant weight gain.
• QT Prolongation: Monitor heart rhythm, particularly in patients with cardiac conditions or those using other medications affecting cardiac conduction.
• Leukopenia/Neutropenia: Regular blood tests may be required to monitor white blood cell counts.
• Caution in Elderly with Dementia-Related Psychosis: Increased mortality risk in elderly patients treated for dementia-related psychosis.
• Avoid Abrupt Discontinuation: Taper gradually to avoid withdrawal symptoms.
• Pregnancy and Nursing: Discuss potential risks with a healthcare provider when used during pregnancy or while breastfeeding.
• CNS Depressants Interaction: Exercise caution when combined with other central nervous system depressants such as opioids or alcohol.

Storage 

• Store Invega at room temperature, usually between 20°C to 25°C.
• Do not store in damp places such as bathrooms. Keep the medication away from direct heat and sunlight.
• Maintain the medication in its original packaging to protect it from light and moisture.
• Ensure the container is tightly closed when not in use to prevent contamination.
• Store Invega out of reach of children and pets to prevent accidental ingestion.

Invega Interactions

• CNS depressants (e.g., benzodiazepines, opioids, alcohol)
• Anticholinergic agents (e.g., benztropine, atropine)
• Antiarrhythmics (e.g., amiodarone, quinidine)
• Antihypertensive agents (e.g., beta-blockers, ACE inhibitors)
• Levodopa and dopamine agonists (e.g., pramipexole, ropinirole)
• QT-prolonging drugs (e.g., azithromycin, sotalol)
• Carbamazepine (may reduce the levels of Invega)
• Rifampin (may reduce the effectiveness of Invega)
• Phenytoin (may reduce the levels of Invega)
• Fluoxetine (may increase the levels of Invega)
• Paroxetine (may increase the levels of Invega)
• Itraconazole (may increase the levels of Invega)

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

Invega Alternatives

• Other atypical antipsychotics:
  • Risperdal (risperidone)
  • Zyprexa (olanzapine)
  • Seroquel (quetiapine)
  • Abilify (aripiprazole)
  • Geodon (ziprasidone)
  • Latuda (lurasidone)
  • Vraylar (cariprazine)
• Typical antipsychotics:
  • Haldol (haloperidol)
  • Thorazine (chlorpromazine)
  • Prolixin (fluphenazine)
• Long-acting injectable antipsychotics:
  • Risperdal Consta (risperidone)
  • Abilify Maintena (aripiprazole)
  • Zyprexa Relprevv (olanzapine)
• Other medications (depending on the specific condition):
  • Mood stabilizers (e.g., Depakote (valproic acid), Lithobid (lithium))
  • Antidepressants (e.g., Prozac (fluoxetine), Zoloft (sertraline))

Note: Your healthcare provider will choose which Invega alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions 

How long does it take for Invega to start working?

You may feel an improvement in your mood within the first week of starting Invega, but achieving the full therapeutic effects might take longer. If you do not notice any significant improvements, it’s essential to discuss this with your healthcare professional, who may adjust your dosage or explore alternative treatments. Typically, finding the optimal dosage of Invega when starting treatment can take several weeks.

Can Invega cause erectile dysfunction? 

There is a potential for Invega to lead to erectile dysfunction (ED), primarily because it can increase prolactin levels, which is known to impact sexual function. While there are no documented cases of ED in clinical trials, users should be aware of this possibility. Another profound sexual side effect is priapism, an erection lasting more than four hours. Immediate medical attention is necessary for priapism to prevent permanent damage.

How long does Invega remain in your system? 

Most of Invega is typically eliminated from your body within 5 days after discontinuation. However, this duration can vary based on overall health and genetic makeup. The medication’s half-life informs this estimate, but personal variations can alter this timeline. If you have concerns about how long Invega stays in your system, it’s best to consult your healthcare provider.

Should you drink alcohol while on Invega? 

It is recommended to avoid alcohol when taking Invega, as it can intensify specific side effects, including dizziness and drowsiness. Additionally, alcohol can exacerbate mental health conditions such as schizophrenia.

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