Adalimumab
Humira
Humira is a medication approved by the FDA to treat multiple conditions such as including rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. It is available in the form of pre-filled pens, syringes & vials, which come in varying strengths. It works by blocking tumor necrosis factor and reducing pain, inflammation, and damage caused by the conditions. For a safe and efficient use of the medicine, you should talk to your doctor and seek guidance related to dosage, storage, and more.
Product Overview
Humira is a medication primarily used to treat multiple inflammatory conditions, including psoriatic arthritis, rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. It contains adalimumab, a biologic agent that targets and inhibits tumor necrosis factor (TNF), a protein involved in inflammation. By blocking TNF, Humira helps reduce inflammation, pain, and damage caused by these conditions.
Humira is available in a strength of 40 mg per injection. It is administered as an injection subcutaneously (under the skin), either by a healthcare professional or at home by the patient. The recommended Humira dosage varies depending on the condition being treated, and your doctor will provide specific instructions. Adults and children over the age of 2 may be eligible for treatment, depending on the condition.
Common side effects of Humira may include injection site reactions, headaches & infections. Precautions should be taken for those with a history of infections or certain medical conditions. For missed doses, take it as soon as you remember unless it’s close to the next scheduled dose. Store Humira in the refrigerator and follow all instructions carefully.
What Are the Uses of Humira?
It is used to treat a variety of inflammatory conditions including:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Plaque psoriasis
- Crohn’s disease
- Ulcerative colitis
- Hidradenitis suppurativa
What Are the Benefits of Humira?
- It helps alleviate symptoms, improve physical function & enhance the quality of life for patients with these chronic conditions.
What Are the Side Effects of Humira?
Common Humira side effects may include:
- Injection site reactions (rash, redness, swelling, itching, or bruising)
- Headaches
- Upper respiratory infections (such as sinus infections & the common cold)
- Rashes
[Note: The above list is not complete; if you have any other symptoms that are not mentioned here, immediately consult your doctor.]
What Are the Forms & Strengths of Humira?
It comes in the following forms and strengths:
Form: Single-dose pen
Strengths: 40 mg/0.4 ml, 40 mg/0.8 ml, and 80 mg/0.8 ml
Form: Single-dose prefilled syringe
Strengths: 10 mg/0.1 ml, 10 mg/0.2 ml, 20 mg/0.2 ml, 20 mg/0.4 ml, 40 mg/0.4 ml, 40 mg/0.8 ml, and 80 mg/0.8 ml
Forms: Single-dose vial of liquid solution
Strength: 40 mg/0.8 ml
What Is the Typical Dosage of Humira?
Dosage for Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis
- You should take 40 mg every alternative week.
Dosage for Juvenile Idiopathic Arthritis or Pediatric Uveitis
- The medication dosage is typically based on weight, such as 10 mg every other week for 10-15 kg, 20 mg every other week for 15-30 kg, and so on.
Dosage for Crohn’s Disease
- 160mg on Day 1, followed by 80mg two weeks later, then 40mg every other week.
Dosage for Ulcerative Colitis
- 160mg on Day 1, followed by 80mg two weeks later, then 40mg every other week.
Dosage for Plaque Psoriasis or Uveitis
- The initial recommended dosage is 80mg, followed by 40mg every other week starting one week after the initial dose.
How to Take Humira?
- To understand how to use Humira for the first time and each time you get a refill, refer to the patient information leaflet and, if available, the medication guide. If you have any queries regarding the leaflet, ask your doctor.
- The Humira syringe kit is for subcutaneous use only and should be injected in the thigh or abdomen area.
- The dose of Humira is based on your condition and response to treatment. In pediatric patients, it may also be based on weight.
- During the initial days of treatment, your doctor may prescribe you a lesser dose and increase your dosage gradually if you are being treated for certain conditions.
- Before using this medicine, you should check this product for discoloration or particles. If either is present, you should not use the liquid.
- You should use this medicine regularly to get the most benefit from it.
- Inform your doctor if your condition does not get better or gets worse.
What to Do When You Miss a Dose of Humira?
- If you miss a dose of Humira, you should take it as soon as you think of it; however, omit it if it is almost time to use your next scheduled dose.
- You can set a medication reminder on your mobile phone to prevent missing doses further.
[Note: Do not take two doses of Humira simultaneously to match up a missed dose. This can increase your risk of experiencing unfavorable side effects.]
What Happens When You Overdose on Humira?
It is not recommended to inject Humira more than the prescribed dose. If someone has overdosed and is having severe symptoms, including trouble breathing or loss of consciousness, immediately seek medical attention. Call a medical professional or 911. You can also visit the nearest hospital.
[Note: If you suspect you may have taken too much Humira, call your local emergency number immediately.]
How Does Humira Work?
Humira (adalimumab) works by targeting and blocking a specific protein in the body known as tumor necrosis factor (TNF). TNF is involved in causing inflammation and immune system responses. By blocking TNF, Humira helps reduce inflammation, relieving symptoms like pain, swelling & redness associated with various autoimmune conditions such as Crohn’s disease, rheumatoid arthritis & psoriasis.
What Are the Important Safety Precautions of Humira?
- This medicine can increase your susceptibility to fungal infections and tuberculosis. Stay away from people who may have an infection.
- There is a small chance, especially in young people, that this medication may increase the risk of cancer, like lymphoma or skin cancer.
- Before using this medication, tell your doctor if you’re allergic to it or have any allergies. It may contain ingredients that may cause allergic reactions.
- Older adults may be more at risk for infections and cancer while using Humira.
- During pregnancy, this medication should only be used if absolutely necessary, as it may harm the baby. Talk to your doctor about the risks. If you have used this medication during pregnancy, ask your doctor about vaccinations for your baby.
- Humira can pass into breast milk, so consult your doctor before breastfeeding.
How Do You Store Humira?
- You can keep Humira in the refrigerator, but do not allow it to freeze.
- Keep it in its original packaging to protect it from light and extreme temperatures.
- Ask your doctor, medical provider, or pharmacist if you can keep Humira at room temperature.
- You should not keep unwanted or unused portions of the medicine and keep it away from the sight and reach of pets and children.
What Drugs Interact with Humira?
- Infliximab
- Etanercept
- Anakinra
- Abatacept
- Cyclosporine
- Warfarin
- Prednisone
- Mycophenolate mofetil
- Corticosteroids
- Biologic DMARDs
[Note: The above list of interactions is not complete. Get in touch with your doctor if you notice any interaction with food items, over-the-counter drugs, prescription medicines, or supplements.]
What Are the Humira Alternatives?
- Methotrexate
- Remicade (infliximab)
- Orencia (abatacept)
- Rituxan (rituximab)
- Xeljanz (tofacitinib)
- Stelara (ustekinumab)
- Omvoh (mirikizumab)
- Skyrizi (risankizumab)
[Note: Your healthcare provider will choose which Humira alternative is most suitable for you. Consuming them by yourself may cause adverse side effects.]
Humira Cost & Coupons
The price to buy Humira (adalimumab) online can vary depending on multiple factors such as health insurance coverage plan, prescription type, and pharmacy. Many Americans find that their health insurance plan does not cover medications like Humira, thus leading to significant out-of-pocket expenses. To manage financial burden, some Americans turn to online platforms such as Arctic Meds, which enables them to buy Humira online from Canada in the USA at a reduced price and have it delivered to their doorstep conveniently.
Frequently Asked Questions
What are the worst side effects of Humira?
In rare cases, Humira can cause severe side effects such as nervous system issues, heart failure, liver issues, lupus-like syndrome, new or worsening psoriasis, or reactivation of hepatitis B virus.
Is Humira a lifelong drug?
If your doctor determines that this medication is safe for you to use, they will prescribe it for you to use for the long term. However, they will closely monitor you to decide if Humira is working as well as it should and if you should continue using it.
Can Humira cause hair loss?
Yes, it is possible that Humira can cause hair loss in some people using it, but it’s rare, and the data is limited. You should talk with your doctor if you are concerned about hair loss while taking Humira.
How soon does Humira start working?
Humira may start to show benefits in some people using it in as little as two weeks after starting to use it.
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