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Metformin hydrochloride 


Glucophage, known by its generic name as metformin, is a biguanide primarily used to treat Type 2 diabetes mellitus. The prescription medication approved by the FDA effectively improves glycemic control in individuals with type 2 diabetes. It is available in the form of a tablet that comes in different strengths. The dosage of the medication is based on the patient’s age, condition, tolerability, and body’s response to treatment. For a safe and efficient use of the medication, consult your physician or healthcare provider. To know more about how you can buy Glucophage to treat type 2 diabetes at affordable prices, head to our website. 

Product Overview 

Glucophage, containing the active ingredient metformin, is a biguanide medication used primarily for managing Type 2 diabetes mellitus. Metformin improves glycemic control by enhancing cellular insulin sensitivity and decreasing hepatic glucose production.

Available in strengths of 500 mg, 850 mg, and 1000 mg, Glucophage is taken orally with water after meals. The initial dosage typically starts at 500 mg twice daily or 850 mg once daily, gradually increasing as needed. It is suitable for adults and children over 10 years old diagnosed with Type 2 diabetes. 

Common side effects include diarrhea, drowsiness, headache, and nausea. Patients should avoid alcohol and monitor for symptoms of lactic acidosis. If a dose is missed, take it as soon as possible unless it’s near the next scheduled dose; do not double doses. Store the Glucophage in its original container, away from heat and moisture, and out of reach of children. For proper disposal of unused medication, consult your pharmacist or local waste disposal company. Always follow your healthcare provider’s guidance for safe use.

Uses of Glucophage

It is used to treat:

  • Type 2 diabetes mellitus 

Benefits of Glucophage

  • It helps in controlling blood glucose levels.
  • Managing your blood sugar levels will reduce the risk of serious complications associated with diabetes, such as nerve damage, eye problems, kidney-related issues, and loss of limbs. 
  • Taking this medication, alongside a proper diet plan and regular exercise, will help you lead a healthy and balanced life.

Side Effects of Glucophage

Common side effects of Glucophage may include:

  • Diarrhea
  • Drowsiness 
  • Headache 
  • Fatigue 
  • Itching 
  • Rashes
  • Nausea

[Note: This list is not exhaustive; if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]

Glucophage Dosage

Forms & Strengths

It comes in the form of a tablet with the following strengths:

  • 500 mg
  • 850 mg
  • 1000 mg

Recommended Dosages

Dosage for Type 2 Diabetes Patients
  • Usual initial daily dose: 500 mg orally twice daily or 850 mg once daily, taken with a meal. 
  • Your doctor will gradually increase the dosage by 500 or 850 mg every two weeks, depending on your body’s response to treatment, age, and condition. 
  • Maximum daily dose: 2550 mg daily given once or in divided dosage. 
  • Dosages above 2000 mg have better tolerability when given thrice daily with food. 

How to Take Glucophage?

  • Before starting to take Glucophage, you should carefully read and follow the directions for use given in the patient information leaflet that came along with your prescription medication. 
  • If you have any questions or concerns about using the medication, consult your healthcare provider or physician. 
  • You should take Glucophage exactly as directed by your doctor orally by mouth with a glass of water after a meal. 
  • Do not take Glucophage more or less than prescribed, in large quantities or more frequently, as it can lead to unwanted side effects. 
  • Do not cut, crush, chew, or break the Glucophage tablet. Swallow it whole.
  • Do not stop taking this medication abruptly without consulting your doctor. 
  • You should not consume alcohol while you are taking this medication, as it may affect your blood sugar levels. 
  • Do not share this medication with others, even if they have the same symptoms as you. 

Missed Dose 

  • If you missed a dose of Glucophage, you should take it as soon as you remember. 
  • However, if it is almost time for your next dose, you may omit the missed dose and take the next dose according to your dosage schedule. 
  • Do not take two doses of the same medication to compensate for the missed dose. 
  • You can set a reminder on your phone to prevent missing doses. 

[Note: Do not take two doses of Glucophage at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]


If you think you have overdosed on this medication, you may experience hypoglycemia. Its symptoms may include extreme fatigue, drowsiness, sweating, nausea, diarrhea, and vomiting. You should seek immediate medical assistance if you experience any of these symptoms. You can call 911 or head to the nearest emergency room. 

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Glucophage Work?

Glucophage, also known as metformin, increases the ability of cells to take up glucose by improving their insulin sensitivity, allowing them to absorb glucose from the bloodstream efficiently. It also decreases the amount of glucose produced by the liver. Typically, the liver releases glucose into the bloodstream, but metformin helps regulate this process, preventing excessive glucose production. Additionally, metformin reduces the absorption of glucose from the intestine. By limiting the entry of glucose from the digestive system, it helps maintain stable blood sugar levels.

Important Safety Precautions

  • Lactic acidosis usually occurs during an acute worsening of renal function, a cardiorespiratory disease, or sepsis. Metformin accumulation raises the risk of lactic acidosis, which occurs when renal function is acutely worsened.
  • You should not take this medication if you have severe renal impairment, hypersensitivity to metformin, or diabetic ketoacidosis, with or without coma.
  • You should temporarily discontinue taking this medication if you experience severe diarrhea, dehydration, reduced fluid intake, or fever, and call your doctor at once. 
  • Patients with heart, liver, or kidney-related conditions should consult their doctor before taking this medication and should be carefully monitored if they decide to take the medication. 
  • If you are planning to undergo surgery, you should discontinue taking the medication and restart taking it after 48 hours of surgery. 
  • Before using this medication for pediatric patients, a diagnosis of type 2 diabetes should be confirmed. Children aged between 10 and 12 years should be cautiously prescribed this medication after weighing the benefits and risks of the medication. 
  • You should regularly check your blood glucose levels while receiving treatment with this medication. 
  • This medication may pass into breast milk and cause harm to the nursing infant. You should consult your physician or healthcare provider before taking this medication while breastfeeding a baby. 
  • When used along with other antidiabetic medications and insulin, Glucophage may cause hypoglycemia. 


  • You should keep the Glucophage in its original container away from direct sunlight, moisture, and excess heat. 
  • Do not keep it in the bathroom or the car, as heat and dampness may harm certain medications. 
  • Store the medication in a safe place, away from the sight and reach of children and pets. 
  • Do not keep medications that are outdated or no longer needed. Discard them safely. 
  • Do not pour it down the drain, throw it into your household garbage bin, or flush it down the toilet. 
  • Eliminate the unwanted medications in such a way that children, animals, and others cannot consume them. 
  • To learn more about properly disposing of unwanted medications, consult your healthcare provider, pharmacist, or local waste disposal company. 

Glucophage Interactions

Certain medications may interact with Glucophage and affect how it may work. 

  • Acetazolamide
  • Alcohol
  • Certain antivirals for HIV or hepatitis
  • Cimetidine
  • Dichlorphenamide
  • Digoxin
  • Diuretics
  • Dofetilide
  • Estrogens
  • Glycopyrrolate
  • Isoniazid
  • Lamotrigine
  • Memantine
  • Methazolamide
  • Metoclopramide
  • Midodrine
  • Niacin
  • Phenytoin
  • Ranolazine
  • Thyroid medications
  • Topiramate
  • Trospium
  • Vandetanib
  • Zonisamide

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

Glucophage Alternatives

  • Januvia (sitagliptin)
  • Mounjaro (tirzepatide)
  • Nesina (alogliptin)
  • Ozempic (semaglutide)
  • Rybelsus (semaglutide)
  • Tradjenta (linagliptin)
  • Trulicity (dulaglutide)
  • Victoza (liraglutide)

[Note: Your healthcare provider will choose which Glucophage alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

Can Glucophage be used in combination with other diabetes medications?

Yes, Glucophage (metformin) can be used alongside other diabetes medications, including insulin and sulfonylureas. However, combining medications increases the risk of hypoglycemia, so close monitoring and adjustment by your healthcare provider are essential.

Does Glucophage cause weight loss?

Glucophage can assist with weight loss in some patients by reducing appetite and improving insulin sensitivity. However, it is not primarily prescribed for weight loss and should be used as part of a comprehensive diabetes management plan.

Is it safe to take Glucophage during pregnancy?

Consult your healthcare provider before taking Glucophage during pregnancy. While some studies suggest it is safe, your doctor will evaluate the benefits and potential risks based on your specific condition.

How long does it take for Glucophage to start working?

Glucophage typically begins to lower blood glucose levels within 48 hours of starting the medication. However, it may take up to two weeks to see the full effect. Regular monitoring of blood glucose levels is important to assess the medication’s efficacy.

Our Guarantee

At Arctic Meds, we guarantee that you will find the most competitive prices for purchasing Glucophage through our platform. As the best Canadian online pharmacy, we are committed to delivering only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Glucophage online from Canada at a low price contact us.


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Refrigerated items $29.99
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