Galcanezumab
Emgality Auto-injector Prefilled Syringe
Emgality (galcanezumab) is used to prevent migraines and treat cluster headaches. It is administered through an auto-injector, offering convenient home use. The drug works by blocking a protein involved in transmitting pain signals, thereby reducing headache frequency and severity. Emgality is generally well-tolerated, with manageable side effects like injection site reactions and nausea. It requires monthly injections and has minimal drug interactions, making it a reliable option for those suffering from severe headaches. You can only buy Emgality online from Canada with a prescription that you may get from a healthcare professional.
Product Overview
Emgality (galcanezumab) is a specifically designed medication that targets and blocks the calcitonin gene-related peptide (CGRP), a key player in migraine and cluster headache pathophysiology. By inhibiting this peptide, Emgality effectively reduces the frequency and intensity of headache episodes.
The medication is administered via a user-friendly auto-injector, which comes in prefilled syringes or pens, allowing patients to self-administer the drug at home without professional help. Common side effects include injection site reactions, rash, and nausea, but these are typically mild and manageable.
Emgality offers significant benefits for those with difficult-to-treat migraines or cluster headaches, providing a reduction in the number of headache days and potentially improving quality of life. It is essential for users to have a valid prescription from their doctor to buy Emgality online to prevent migraine.
What Are the Uses of Emgality?
- Prevent migraines
- Treat cluster headaches, which are intense headaches that usually affect one side of the head.
What Are the Benefits of Emgality?
- Convenient self-administration at home without professional assistance.
- Only one injection is required per month, improving adherence to treatment.
- Few drug interactions, minimizing risks to the liver or kidney.
- Proven to reduce migraine frequency and the number of headache days.
- Effective in reducing the frequency of cluster headaches.
- Generally well-tolerated with minimal side effects.
What Are the Side Effects of Emgality?
Common Emgality side effects may include:
- Injection site reactions like pain, redness, or swelling
- Itching
- Rash
- Nausea
- Fatigue
- Constipation
- Skin discoloration
- Runny nose
- Sinus and throat infections
- Back & joint pain
[Note: This list is not exhaustive; if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
What Are the Forms & Strengths of Emgality?
Emgality Auto-injector comes in two forms (prefilled syringes and pens) with two strengths such as:
- 100mg/mL
- 120mg/mL
What Is the Typical Dosage of Emgality?
For Migraine Prevention
- Start with a total dose of 240 mg, which means two injections of 120 mg each.
- After that, take 120 mg as a single injection once a month.
For Episodic Cluster Headaches
- When a cluster period starts, take 300 mg as the first dose.
- Then, take 300 mg once a month until the cluster period ends.
How to Take Emgality?
- Read the patient information leaflet carefully before using the Emgality Auto-injector.
- Consult your doctor or pharmacist with any questions about using the medication.
- Take Emgality as a subcutaneous injection once a month.
- Initially, learn to self-inject under your healthcare provider’s guidance.
- Start with two or three injections at home or a doctor’s office.
- For migraine prevention, inject once a month at home.
- For cluster headache treatment, inject three times a month.
- Emgality comes in single-dose prefilled syringes and pens, which are disposable after one use.
- After removing the medication from the refrigerator, let it warm for 30 minutes; do not heat it using a microwave or hot water.
- Inspect Emgality for discoloration or particles before use, and do not use if these are present.
- Do not shake or freeze the auto-injector.
- Clean the injection site with rubbing alcohol before injecting.
- Rotate injection sites to avoid repeated use of the same area.
- Avoid injecting into damaged, tender, red, hard skin that has scars or stretch marks.
- Inject under the skin in the abdomen, thighs, lower arms, or buttocks as directed.
- Dosage depends on the treated condition and body response.
- Use the auto-injector regularly for best results.
- Inform your doctor if your condition does not improve or worsens.
What to Do When You Miss a Dose of Emgality?
If you miss a dose, take the medicine as soon as you remember, then return to your regular injection schedule one month later.
[Note: Do not take two doses of Emgality at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]
What Happens When You Overdose on Emgality?
If you think you’ve overdosed on Emgality Auto-injector, get medical help right away. For severe symptoms like trouble breathing, seizures, or passing out, call 911 or contact the poison control center.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Emgality Work?
Emgality (galcanezumab) is a medication that helps to prevent migraines and treat episodic cluster headaches by targeting and blocking a specific protein called CGRP (calcitonin gene-related peptide). CGRP plays a key role in transmitting pain signals within the nervous system, particularly during migraine attacks. Emgality works by binding directly to CGRP, effectively preventing it from attaching to its receptor. By blocking this interaction, Emgality reduces the activation of pain pathways, helping to prevent or reduce the severity of migraines and cluster headaches.
What Are the Important Safety Precautions for Emgality?
- Inform your doctor about any allergies to the medication or its ingredients.
- Emgality may contain inactive ingredients that can cause allergic reactions or other issues; ask for a full list of ingredients.
- Discuss your complete medical history with your healthcare provider.
- Notify your doctor, surgeon, or dentist about using the Emgality Auto-injector if you plan to have surgery, including any other medications, supplements, or herbal treatments you are taking.
- Use this medication during pregnancy only if clearly needed, and discuss all risks and benefits with your doctor.
- Consult your doctor before breastfeeding while on this medication, as it is unknown if galcanezumab passes into breast milk.
How Do You Store Emgality?
- Store Emgality Auto-injector in the refrigerator at 36°F-46°F (2°C-8°C).
- Do not freeze. If frozen, discard it safely.
- It can be stored at room temperature (up to 86°F or 30°C) for up to 7 days.
- Discard it if not used within 7 days at room temperature.
- Keep it in its original container to protect it from sunlight.
- Store away from direct light, moisture, and heat.
- Do not shake the auto-injector.
- Take it out of the refrigerator 30 minutes before use to let it warm up.
- Do not use heat sources like microwaves or hot water to warm it.
- Do not use it if the expiration date has passed.
- Check the liquid before use; do not use it if it is cloudy, discolored, or has particles.
- Dispose of used injectors in an FDA-approved sharps container.
What Drugs Interact with Emgality?
- Sumatriptan
- Erenumab
- Rizatriptan
- Naproxen
- Fremanezumab
- Zolmitriptan
- Ergotamine
- Eptinezumab
- Dihydroergotamine
- Ibuprofen
- Aspirin
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]
What Are the Emgality Alternatives?
- Amitriptyline (amitriptyline)
- Qulipta (atogepant)
- Verapamil (verapamil)
- Topiramate (topiramate)
- Botox (onabotulinumtoxin A)
- Valproic acid (valproic acid)
- Gabapentin (gabapentin)
- Aimovig (erenumab)
- Metoprolol (metoprolol)
- Ajovy (fremanezumab)
- Nurtec ODT (rimegepant)
- Candesartan (candesartan)
- Propranolol (propranolol hydrochloride)
- Vyepti (eptinezumab)
[Note: Your healthcare provider will choose which Emgality alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Emgality Cost & Coupons
Emgality, prescribed for migraine prevention and cluster headache treatment, can be quite expensive in the U.S., often costing significant amounts monthly without insurance. To ease this financial strain, choose to buy Emgality online from Canada through Arctic Meds. We provide Emgality at much lower costs, directly benefiting U.S. residents in search of more affordable healthcare options. Additionally, apply the Emgality coupon code “ARCTIC10” to receive an extra 10% off your initial order. Participate in our referral program to save further, potentially reducing your medication expenses by up to $200.
Frequently Asked Questions
Will Emgality stop a migraine?
Emgality is designed to prevent migraines by blocking a protein called CGRP, which is involved in causing migraines. While it’s effective in preventing the onset of migraines, it is not intended to relieve migraine symptoms once a migraine has already begun.
Does Emgality work immediately?
Emgality can start to reduce the frequency of migraines as early as one week after beginning the treatment, enhancing quality of life significantly. However, results can vary, and it’s important to discuss with your doctor the reasons Emgality has been prescribed for you.
What happens if you stop taking Emgality?
For those using Emgality for episodic cluster headaches, you may stop during remission periods without issue. However, stopping it during an active period might cause your symptoms to return to their original levels.
Where is the best place to inject Emgality?
Emgality should be injected under the skin. The most recommended sites for injection are the stomach area (avoiding two inches around the belly button) and the front part of the thigh (making sure to stay two inches above the knee and two inches below the groin).
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