Elagolix

Orilissa

Used to manage moderate to severe endometriosis pain, Orilissa is an oral medication. It is prescribed to relieve pelvic pain and painful intercourse by lowering estrogen levels. Available in multiple dosages of 150 mg & 200 mg, this medication helps control endometrial tissue growth. You can check out alternatives and interactions of this medication below. Given its out of the pocket prices in the US, residents now buy Orilissa online from Canada to save on costs without compromising on medication authenticity.

Product Overview 

Orilissa is an oral medication used to manage mild to severe endometriosis pain. It helps alleviate signs such as menstrual pain, pelvic pain, and painful intercourse (dyspareunia) by reducing estrogen levels in the body. Available in 150 mg & 200 mg strengths, Orilissa provides a non-surgical treatment option for endometriosis. 

Common side effects can be seen like hot flashes, headaches, nausea, and mood changes. Long-term use may decrease bone density, so following the prescribed duration is essential. Orilissa works by suppressing gonadotropin-releasing hormone (GnRH), which regulates estrogen production, thereby reducing the growth of endometrial tissue and associated pain. 

Monitoring bone density and mental health while taking this medication is crucial. Many individuals buy Orilissa online from Canada through trusted services to manage costs, which can provide significant savings. Always talk to your medical professional to get a better idea of Orilissa dosage, potential interactions and alternatives.

What Are the Uses of Orilissa? 

• Management of moderate to severe endometriosis pain
• Reduction of menstrual pain
• Treatment of pelvic pain
• Alleviation of painful intercourse (dyspareunia) associated with endometriosis

What Are the Benefits of Orilissa? 

• Reduces endometriosis pain
• Helps alleviate pelvic pain
• Decreases painful menstrual cramps
• Improves quality of life by managing endometriosis symptoms
• Non-surgical treatment option for endometriosis
• Provides relief from Dyspareunia

What Are the Side Effects of Orilissa? 

Common Orilissa side effects may include:

• Hot flashes
• Headache
• Nausea
• Fatigue
• Night sweats
• Insomnia
• Joint pain
• Mood changes, including depression or anxiety
• Decreased bone density (with long-term use)

[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Orilissa Dosage

What Are the Forms & Strengths of Orilissa?

• Forms: Oral tablets 
• Strengths: 150 mg and 200 mg

What Are the Recommended Dosages of Orilissa?

For Moderate Endometriosis Pain

• Dosage: This medication is prescribed as 150 mg once daily.
• Duration: Orilissa should be taken for 24 months to get lasting results.

For Severe Endometriosis Pain

• Dosage: The dosage strength is increased to 200 mg twice daily for intense pain.
• Duration: Medical professionals recommend taking this medication for up to six months.

Duration Limitations

• Use is limited due to the risk of decreased bone density, especially with higher or longer-term doses. It’s important to follow your healthcare expert’s instructions and not exceed the recommended treatment duration.

How to Take Orilissa? 

• Swallow the tablet with water; no need to break or chew it.
• It can be taken regardless of meals, before or after.
• Take Orilissa at the same time each day for the best results.
• Do not exceed the recommended duration to avoid any side effects.

What to Do When You Miss a Dose of Orilissa? 

If you miss a dose of Orilissa, take it as soon as you remember on the same day. If it is close to your upcoming dose, skip the missed dose and keep on with your regular dosing schedule. Do not double up on doses of this medication to make up for the missed one. If you happen to miss your doses very often, consider setting up a timer so you do not miss any.

[Note: Do not simultaneously take two doses of Orilissa to compensate for a missed dose. This can elevate your risk of experiencing side effects.]

What Happens When You Overdose on Orilissa?

If you exceeded that prescribed dosage of Orilissa, you may experience an increase in side effects such as hot flashes, headaches, mood changes, and nausea. In case of a medication overdose, do not attempt to self-manage it. Monitoring for unusual symptoms and following medical advice is essential to ensure safe recovery.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Orilissa Work?

Orilissa works by slowing down the production of certain hormones, explicitly gonadotropin-releasing hormone (GnRH), which is responsible for regulating the release of estrogen in the body. By lowering estrogen levels, Orilissa helps reduce the symptoms of endometriosis, like pain and inflammation, since estrogen plays a vital role in the growth of endometrial tissue. This hormonal regulation provides33 relief from moderate to severe endometriosis-related pain.

Important Safety Precautions

• Monitor bone density: Prolonged use of this medication may lead to bone loss.
• Not for pregnant women: This medication is not recommended as it can harm an unborn baby.
• Mental health: Monitor for mood changes, depression, or suicidal thoughts.
• Liver function: Regular liver monitoring may be required.
• Avoid use beyond recommended duration: Risk of severe side effects increases.
• Consult your doctor: Before taking, especially if you have a history of osteoporosis or depression.

How to Store Orilissa?

• Store this medication at a temperature ranging between 68°F to 77°F.
• Keep this medication protected from moisture and direct sunlight.
• Avoid storing Orilissa in the bathroom and other humid-prone areas as it can affect the efficacy of this medication.
• Keep the medicine stored out of reach of children and pets.
• Check expiration dates regularly and see if the medicine is past its expiration date.

What Medications Interact with Orilissa? 

• Hormonal contraceptives (e.g., birth control pills, patches, injections)
• Gonadotropin-releasing hormone (GnRH) agonists (e.g., leuprolide)
• Antiepileptic drugs (e.g., carbamazepine, phenytoin)
• CYP3A inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
• CYP3A inducers (e.g., rifampin, St. John’s wort)
• Statins (e.g., simvastatin, atorvastatin)
• Digoxin
• Cyclosporine
• Tacrolimus
• Anticoagulants (e.g., warfarin)
• Antidepressants (e.g., fluoxetine, sertraline)
• Blood pressure medications (e.g., lisinopril, losartan)
• HIV protease inhibitors (e.g., ritonavir, saquinavir)
• Macrolide antibiotics (e.g., erythromycin, clarithromycin)
• Antifungal medications (e.g., fluconazole, voriconazole)

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

What Are the Orilissa Alternatives? 

Other GnRH antagonists:

• Oriahnn (elagolix/estradiol/norethindrone acetate)
• Myfembree (relugolix/estradiol/norethindrone acetate)

GnRH agonists:

• Lupron Depot (leuprolide acetate)
• Zoladex (goserelin acetate)
• Synarel (nafarelin acetate)

Hormonal contraceptives:

• Combined oral contraceptives (various brands)
• Depo-Provera (medroxyprogesterone acetate)
• Mirena (levonorgestrel-releasing intrauterine system)

Progestins:

• Visanne (dienogest)
• Provera (medroxyprogesterone acetate)
• Norethindrone acetate

Aromatase inhibitors:

• Femara (letrozole)
• Arimidex (anastrozole)

Danazol (danazol)

Non-hormonal pain medications:

• NSAIDs: • Advil or Motrin (ibuprofen) • Aleve (naproxen)
• Tylenol (acetaminophen)

Surgical options:

• Laparoscopic excision of endometriosis lesions
• Hysterectomy (in severe cases)

[Note: Your healthcare provider will choose which Orilissa alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]

Orilissa Cost & Coupons

The cost of Orilissa and the options for obtaining it at a lower price depend on several factors, including health insurance coverage. Many Americans discover their insurance doesn’t cover medications like Orilissa, resulting in high out-of-pocket expenses. To manage these costs, some turn to services like Arctic Meds, where they can buy Orilissa online at a reduced price, making it more affordable for those in the USA.

Frequently Asked Questions

How soon does Orilissa begin to work?

While you may not experience immediate relief from this medication, it may lower hormone levels within 6 hours of taking the first dose. Getting relief from this medication may take upto a few months, so maintain consistency. If you face any concerning situation, consult your healthcare specialist.

When should I begin taking Orilissa?

Your healthcare provider will instruct you to start taking Orilissa within 7 days after the start of your period. If you begin outside this time frame, your provider will likely have you take a pregnancy test to confirm you’re not pregnant before starting the medication.

Can I have children after stopping Orilissa?

Orilissa doesn’t permanently affect your ability to have children. Still, it can be harmful to an unborn baby, which is why your provider will ensure you’re not pregnant before starting it. After stopping Orilissa, your estrogen levels will return to normal within one to two days. However, you should continue using non-hormonal birth control for 28 days after discontinuing the medication to prevent pregnancy.

What type of birth control should I use with Orilissa?

While taking Orilissa and for 28 days after stopping, it’s recommended to use non-hormonal birth control methods like condoms or spermicide to prevent pregnancy. Orilissa can reduce the effectiveness of hormonal birth control and vice versa. Additionally, hormonal contraceptives containing estrogen can increase estrogen exposure, potentially leading to side effects like blood clots. The effectiveness of progestin-only methods, like injections or implants, with Orilissa is unclear.

Our Guarantee

At Arctic Meds, we guarantee you will find the most competitive prices for purchasing Orilissa through our platform. As the best Canadian online pharmacy, we are all about delivering only the highest quality products. Each order is fulfilled through a reputable and licensed Canada pharmacy online, ensuring that every product we ship meets stringent standards of quality and authenticity. Our reliable service ships your medications directly from Canada right to your doorstep. For seamless access to buy Orilissa online from Canada at a low price contact us.

IMPORTANT NOTE: The information available on the Arctic Meds website is intended to enhance awareness about healthcare products and medical conditions. It is for informational purposes only. Always consult a qualified healthcare professional before using any prescription or non-prescription medication. Our platform offers access to a broad selection of products that are sourced from various countries including Canada. We operate with both a licensed partnered pharmacy located in Canada along with reputable dispensing pharmacies located globally. All affiliated fulfillment centers are approved by the regulatory bodies of their respective countries.