Duloxetine

Buy Cymbalta Online

Cymbalta (duloxetine) is an FDA-approved medication primarily used to treat fibromyalgia, generalized anxiety disorder, major depressive disorder, diabetic neuropathy pain, and chronic musculoskeletal pain in adults. It’s also approved for treating generalized anxiety disorder and fibromyalgia in particular children. Available in delayed-release capsules, Cymbalta helps balance natural brain substances, such as serotonin and norepinephrine. Potential side effects include insomnia, sexual dysfunction, and dizziness. It must not be crushed, split, or chewed. You can buy Cymbalta from Canada with a valid prescription that you can quickly get from your doctor. 

Product Overview

Cymbalta contains the active ingredient duloxetine, and it is prescribed for the treatment of fibromyalgia, generalized anxiety disorder, major depressive disorder, diabetic neuropathy pain, and chronic musculoskeletal pain among adults. It is also approved for treating generalized anxiety disorder in children aged seven and older and fibromyalgia in those 13 and older. 

This drug belongs to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs) and functions by restoring the balance of serotonin and norepinephrine in the brain to help improve mood and pain symptoms. It is available as delayed-release capsules in strengths of 20, 30, and 60 mg.

Most common side effects of Cymbalta may include insomnia, sexual dysfunction, dizziness, and excessive sweating. It requires careful management of dosages and must not be altered physically (crushed, split, or chewed). Follow prescribing guidelines given by your doctor to avoid potential severe side effects.

What Are the Uses of Cymbalta?

Cymbalta is approved by the FDA to manage various conditions:

• For Adults:

• • • Major Depressive Disorder (MDD)
    • Generalized Anxiety Disorder (GAD)
    • Diabetic Neuropathy Pain
    • Fibromyalgia
    • Chronic Musculoskeletal Pain

• For Children:

• • Generalized Anxiety Disorder (GAD): Ages 7 years and older.
  • Fibromyalgia: Ages 13 years and older.

What Are the Benefits of Cymbalta?

• Helps manage chronic pain conditions such as fibromyalgia and diabetic nerve pain.
• Can provide relief from musculoskeletal pain, like chronic back pain and osteoarthritis pain.
• Often improves both physical and emotional symptoms of depression.
• May help reduce anxiety symptoms and improve mood.
• Can help improve sleep quality and energy levels.
• Usually starts showing effects within 1-4 weeks of consistent use.
• Available in different dosage strengths for individualized treatment.
• Can be taken once daily, making it convenient for patients.
• Can be effective in treating multiple conditions simultaneously.

What Are the Side Effects of Cymbalta?

Common Cymbalta side effects may include:

• Insomnia (trouble sleeping)
• Sexual side effects, that includes loss of libido in females & males & erectile dysfunction in males
• Dizziness
• Hyperhidrosis (excessive sweating)
• Fatigue
• Nausea
• Dry mouth
• Headache
• Decreased appetite
• Sleepiness
• Constipation

[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]

What Are the Forms & Strengths of Cymbalta?

Cymbalta is available in the form of delayed-release oral capsules and are offered in three different strengths:

• 20 mg
• 30 mg
• 60 mg

What Is the Typical Dosage of Cymbalta?

Adult Dosage for Depression

• Starting dose: 40 to 60 mg daily.
  • 40 mg: Take 20 mg twice per day.
  • 60 mg: Take 30 mg twice per day or 60 mg once per day.
• Maximum recommended dose: 120 mg per day, though doses above 60 mg generally do not show additional benefits.

Adult Dosage for Fibromyalgia and Chronic Musculoskeletal Pain

• Start with 30 mg once daily, increasing to 60 mg after one week if needed.
• Maximum dose for effectiveness: 60 mg once per day.

Adult Dosage for Diabetic Neuropathy Pain

• Recommended dose: 60 mg once per day.

Adult Dosage for Anxiety

• Under 65 years: Start with 30 mg once daily, increasing to 60 mg as needed.
• 65 years and older: Start with 30 mg once daily for two weeks, then possibly increase to 60 mg.
• Maximum dose: 120 mg per day, with no additional benefit observed above 60 mg.

Pediatric Dosage (Approved for treating Generalized Anxiety Disorder and Fibromyalgia)

• For GAD in children ages 7 to 17 years: Start with 30 mg once daily, with a possible increase to 60 mg based on the response.
• For fibromyalgia in children ages 13 to 17 years: Start with 30 mg once daily, with an option to increase to 60 mg.

How to Take Cymbalta?

• Always take Cymbalta as directed by your doctor or healthcare provider.
• Cymbalta is available as a delayed-release oral capsule, which means it releases medication into your body after reaching your intestine.
• Depending on your treatment plan, you may take it once or twice daily.
• Try to take Cymbalta at the same time each day to maintain stable levels in your body.
• The optimal time to take Cymbalta can vary based on its use and your daily schedule. Your doctor will advise the best time for you.

• Cymbalta can be taken with or without food.

• Do not crush, split, or chew the capsules. Opened capsules can affect the drug’s effectiveness and increase side effects.

What to Do When You Miss a Dose of Cymbalta?

Take a missed dose as soon as you remember. If it’s close to your next dose, skip the missed dose and resume your regular schedule. Do not double up doses.

[Note: Do not take two doses of Cymbalta at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]

What Happens When You Overdose on Cymbalta?

• Avoid taking more than the prescribed dose. Symptoms of overdose can include drowsiness, seizures, serotonin syndrome, and more.
• In case of overdose, contact your doctor or seek emergency medical attention if symptoms are severe.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Cymbalta Work?

Cymbalta is an SNRI (serotonin-norepinephrine reuptake inhibitor) that helps restore the balance of serotonin and norepinephrine in the brain, important for mood and pain regulation.

What Are the Important Safety Precautions of Cymbalta?

• Birth Control: Discuss contraception if there’s a possibility of pregnancy while on Cymbalta due to potential complications.
• Breastfeeding: Cymbalta enters breast milk and may affect the infant. Monitor for drowsiness or feeding issues in your child.
• Boxed Warning: Cymbalta carries an FDA warning for increased risk of suicidal thoughts, especially in young adults aged 18 to 24.
• Health Conditions: Consult your doctor if you have heart issues, diabetes, liver or kidney problems, closed-angle glaucoma, a history of seizures or convulsions, bipolar disorder, hyponatremia, or conditions affecting stomach emptying as these may require caution or alternative treatments.
• Potential Side Effects: Increased blood pressure, risk of bleeding, and potential for serious eye problems. Regular monitoring is advised.
• Allergic Reactions: Avoid if you have had past allergic reactions to Cymbalta.
• Pregnancy Concerns: Consider alternative treatments as Cymbalta may pose risks during pregnancy.

How Do You Store Cymbalta?

• Store Cymbalta at room temperature, ideally at 77°F (25°C).
• Keep the capsules in a tightly sealed container to protect them from moisture and light.

What Drugs Cannot Be Taken with Cymbalta?

• Serotonin-Risk Drugs (Serotonin Syndrome Risk):

• • • SSRIs: such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac).
    • SNRIs: such as desvenlafaxine (Pristiq), venlafaxine (Effexor XR).
    • Tricyclic Antidepressants: such as amitriptyline, nortriptyline.
    • Triptans: Used for migraines, such as sumatriptan (Imitrex).
    • Pain Medications: such as tramadol, fentanyl.
    • Stimulants: such as amphetamine/dextroamphetamine (Adderall).
    • Other Drugs: Such as buspirone, lithium, monoamine oxidase inhibitors (such as phenelzine).

• Drug Metabolism Inhibitors (CYP1A2 and CYP2D6 Enzyme Inhibitors): 

• • • Strong CYP1A2 Inhibitors: such as fluvoxamine, ciprofloxacin.
    • CYP2D6 Inhibitors: such as fluoxetine, paroxetine.

• Drugs Affecting Blood Clotting:

• • NSAIDs: such as aspirin, ibuprofen, naproxen.
  • Anticoagulants: such as warfarin, rivaroxaban.
• Drugs for Irregular Heartbeat:
  • Examples: flecainide, propafenone.

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

What Are the Alternatives to Duloxetine for Depression?

• Lexapro (escitalopram)
• Prozac (fluoxetine)
• Effexor (venlafaxine)
• Wellbutrin (bupropion)

[Note: Your healthcare provider will choose which Cymbalta alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]

Cymbalta Cost & Coupons

Cymbalta can be expensive in the U.S., with prices often running high without insurance. To mitigate these costs, consider purchasing Cymbalta online from Canada through Arctic Meds. We provide Cymbalta at significantly lower prices, directly benefiting U.S. residents seeking more affordable mental health solutions. When you buy Cymbalta online from Canada through us, use the Cymbalta coupon code “ARCTIC10” to get an extra 10% off your first order. Additionally, our referral program could save you up to $200 on your ongoing medication needs.

Frequently Asked Questions

How long does Cymbalta stay in your system?

Cymbalta typically remains in your system for about three days after the last dose. If you’re concerned about how long its effects last or about possible withdrawal symptoms, it’s a good idea to discuss these with your doctor.

Why is Cymbalta taken at night?

Although Cymbalta is usually taken in the morning, some people may find it beneficial to take it at night, especially if it causes drowsiness during the day. 

Why can’t you drink coffee with Cymbalta?

It’s advisable to avoid coffee and other caffeinated beverages while on Cymbalta. Caffeine is a stimulant that can interfere with sleep and increase the risk of serotonin syndrome, a serious condition resulting from too much serotonin in the body.

What supplements cannot be taken with Cymbalta?

Certain supplements should not be taken with Cymbalta. Tryptophan and St. John’s Wort, for example, can raise serotonin levels in your body, heightening the risk of serotonin syndrome.

How long does it take for Cymbalta to work for pain?

Cymbalta can start relieving pain within two to four weeks, though it might take longer for nerve pain. Some common, usually mild side effects include nausea, dry mouth, headaches, constipation, and drowsiness. These typically diminish after a few weeks.

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