Zuclopenthixol Acetate
Buy Clopixol Acuphase Online
Clopixol Acuphase, containing the active ingredient zuclopenthixol acetate, is an antipsychotic medication used for the initial treatment of short-term psychoses, acute episodes of mental disorders, schizophrenia, and anxiety. It is administered via intramuscular injection by healthcare professionals. Common side effects include drowsiness, dizziness, and abnormal voluntary movements. It works by blocking dopamine receptors in the brain, helping to reduce symptoms like hallucinations and delusions. Clopixol Acuphase requires careful dosage and monitoring, especially in patients with renal or hepatic impairments. Proper storage and awareness of potential drug interactions are crucial for its safe use.
Product Overview
Clopixol Acuphase is a potent antipsychotic medication primarily used for the initial treatment of short-term psychoses, acute episodes of mental disorders, schizophrenia, and anxiety. Its active ingredient, zuclopenthixol acetate, affects neurotransmitters in the brain, particularly dopamine, which is crucial in how we experience pleasure and pain. By blocking dopamine receptors, Clopixol Acuphase helps to normalize brain activity and reduce symptoms such as hallucinations, delusions, and erratic behaviors.
Administered via intramuscular injection, Clopixol Acuphase is designed for rapid action, making it suitable for situations requiring quick control of severe symptoms. Common side effects include drowsiness, abnormal voluntary movements, and weight gain, among others. Patients must be monitored for any unusual symptoms, as the medication can cause significant changes in blood pressure, heart rate, and mental state.
Clopixol Acuphase can interact with various drugs, including alcohol, CNS depressants, antihypertensive medications, and those affecting the QT interval, necessitating a thorough review of the patient’s medication history by healthcare professionals. Proper storage between 15ºC and 25ºC, away from light and moisture, ensures the medication’s efficacy and safety.
Uses of Clopixol Acuphase
Clopixol is used for:
- Treatment of schizophrenia
- Treatment of acute episodes of mental disorders
- Treatment of anxiety
- Initial therapy of short-term psychoses
Benefits of Clopixol Acuphase
- Rapid onset of action for acute psychotic episodes
- Helps control agitation and aggression quickly
- Reduces need for physical restraints in emergencies
- Provides a bridge to long-term antipsychotic treatment
- Allows time for proper diagnosis and treatment planning
- Single injection effective for 2-3 days
- Reduces frequency of medication administration
- Useful for patients with poor oral medication compliance
- Helps stabilize patients for inpatient or outpatient management
- May shorten hospital stays for some patients
Side Effects of Clopixol Acuphase
Common Clopixol Acuphase side effects may include:
- Dry mouth
- Urinary retention
- Drowsiness
- Constipation
- Weight gain
- Tremors
- Increased prolactin level in blood
- Abnormality in voluntary movements
- Stiffness
- Excessive sweating/salivation
- Blurred vision
- Muscle spasm
- Changes in monthly cycles for females
- Dizziness
- Orthostatic hypotension
[Note: This list is not exhaustive, if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Clopixol Acuphase Dosage
Forms & Strengths
Clopixol comes in the following forms and strengths:
- Intramuscular Injection: 50 mg/mL & 200 mg/mL
- Tablet: 10 mg & 25 mg
Recommended Dosages
For Adults
- Typical Dosage: 50-150 mg, or 1-3 ml, every 2-3 days.
- Additional Doses: In some cases, an extra injection may be given within 24 to 48 hours after the first injection.
- Maximum Limits: Do not exceed 400 mg or more than four injections.
- Maintenance Therapy: After the last zuclopenthixol acetate injection, start oral zuclopenthixol within 2-3 days. Begin with about 40 mg daily, which can be split into smaller doses. You can increase the dose by 10-20 mg every 2-3 days, up to 75 mg or more, as needed.
For Older Patients
- Dosage Caution: Use a lower dosage, not exceeding 100 mg per injection.
For Children
- Usage: Not recommended due to lack of sufficient clinical data.
Patients with Renal Impairment
- Dosage: Follow the standard doses as prescribed by your healthcare provider.
Patients with Hepatic Impairment
- Dosage: Use half the recommended dosage. Regular testing of blood serum levels is generally advised.
How to Take Clopixol Acuphase?
- Clopixol Acuphase is an injectable medication given only by healthcare professionals.
- Ensure the healthcare provider is trained to administer deep intramuscular injections.
- The medication should be at room temperature before use.
- Verify the expiration date and check the vial for any damage before use.
- The medication should be drawn into a syringe using an aseptic technique to avoid contamination.
- It is injected directly into the muscle of the buttock or thigh.
- After the injection, gently massage the area to help prevent soreness.
- Alternate the injection sites to avoid muscle damage.
- Watch for any unusual symptoms right after the injection, such as changes in blood pressure, heart rate, or mental state.
- Regularly monitor your mental and physical health, and side effects.
- Be careful when engaging in activities that require alertness, as this medication can cause drowsiness.
Missed Dose
If it’s been less than 6 hours until the next dose, skip the missed dose. If more than 6 hours remain, take the missed dose.
[Note: Do not simultaneously take two doses of Clopixol Acuphase to compensate for a missed dose. This may increase your risk of experiencing side effects.]
Overdose
- Given by medical professionals in a controlled environment, an overdose is unlikely.
- In the rare event of an overdose, medical staff will take necessary actions to manage the situation.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Clopixol Acuphase Work?
Clopixol Acuphase is an antipsychotic medication that primarily influences neurotransmitters and chemicals in the brain that nerve cells use to communicate. One key neurotransmitter it affects is dopamine, which is significantly involved in how we feel pleasure and pain. In conditions like schizophrenia, dopamine pathways in the brain may become overly active, leading to symptoms such as hallucinations, delusions, and unpredictable behaviors. The medication contains zuclopenthixol, an active ingredient that helps manage these symptoms by blocking dopamine receptors in the brain. This blocking helps to normalize dopamine activity and reduce symptom severity. The Acuphase formulation of Clopixol is designed for rapid action. It is administered via injection, enabling it to work quicker than oral forms, which is especially useful for rapidly controlling severe symptoms.
Important Safety Precautions
- Inform your doctor if you have previously used Clopixol or any other schizophrenia treatment and experienced problems.
- Before starting Clopixol, tell your healthcare provider about all other medications you are taking, including over-the-counter drugs, to prevent any harmful interactions.
- Do not use this medication if you regularly consume alcohol.
- Avoid using Clopixol if you have seizures or liver issues.
- If you have dementia, glaucoma, low potassium levels (hypokalemia), or low magnesium levels (hypomagnesemia), discuss all risks and benefits with your doctor before receiving the injection.
- If cardiovascular diseases or blood clots are present in your family history, seek medical advice before using this medication.
- Tell your healthcare provider if you are allergic to any components of Clopixol Acuphase.
- Since Clopixol can impair your attention, avoid driving or engaging in activities that require high levels of alertness.
Storage
- Your healthcare provider or nurse will manage the storage of the injection.
- If stored at home, keep the medication out of reach of children.
- Store the injection in a safe place at temperatures between 15ºC and 25ºC.
- Protect the injection from light and keep it in the original outer carton.
Clopixol Acuphase Interactions
- Neuroleptics and Antihypertensives
- Alcohol and CNS Depressants
- Lithium
- Electrolyte Imbalance Drugs
- Levodopa and Adrenergic Drugs
- Tricyclic Antidepressants
- Metoclopramide and Piperazine
- QT Interval Risks
- CYP2D6 Inhibitors
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Clopixol Acuphase Alternatives
- Stemetil
- Risperdal
- Latuda
- Invega
- Solian
- Stelazine
- Reagila
- Modecate
- Orap
- Nozinan
- Abilify Maintena
- Sycrest
- Neulactil
- Anquil
[Note: Your healthcare provider will choose which Clopixol Acuphase alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
What happens when you stop taking Clopixol?
Stopping Clopixol suddenly can lead to withdrawal symptoms such as nausea, insomnia, and agitation. There’s also a risk that the symptoms the medication was treating, like hallucinations or mood swings, might come back (this is known as rebound or relapse). The body may need time to adjust to not having the medication anymore, which can cause physical discomfort. It’s crucial to consult with a healthcare provider before stopping or changing your dose of Clopixol.
Is Clopixol Depot and Clopixol Acuphase the same?
Clopixol comes in two forms: Clopixol Depot and Clopixol Acuphase, both containing the same active ingredient, zuclopenthixol. However, they are used differently. Clopixol Acuphase is used for quick control of severe mental disorders when other treatments haven’t worked. It acts faster and is used in acute situations. Clopixol Depot is used for ongoing management of conditions like schizophrenia, providing longer-term control.
How much time does Clopixol-Acuphase take to work?
Clopixol-Acuphase starts to have a calming effect about 2 hours after being injected. Its strongest effect occurs around 12 hours after the dose, and these effects can last up to 72 hours. Although it helps manage symptoms, it’s not intended for immediate sedation, as it works gradually.
Does Clopixol have sedative properties?
Clopixol has soothing properties, calming or reducing agitation, restlessness, hostility, and aggression. The level of sedation depends on the dosage given. Higher doses lead to stronger sedative effects, but patients may develop tolerance to these effects over time.
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