Certolizumab Pegol
Cimzia Autoinjector
Cimzia Autoinjector is an FDA-approved medication that is used to manage autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, and plaque psoriasis. It belongs to the TNF blocker class of medications, reducing inflammation and slowing disease progression. The prefilled autoinjector allows for easy self-administration, offering convenience and reducing the need for frequent clinical visits. You can buy Cimzia Autoinjector online from Canada with a valid prescription that you can receive from your doctor.
Product Overview
Cimzia Autoinjector, designed for adult patients, treats a variety of inflammatory autoimmune conditions including rheumatoid arthritis, psoriatic arthritis, Crohn’s disease, ankylosing spondylitis, plaque psoriasis, non-radiographic axial spondyloarthritis, ulcerative colitis, and uveitis.
This medication is a part of the TNF inhibitor class. It effectively reduces inflammation and helps to slow the progression of disease by targeting and neutralizing tumor necrosis factor (TNF), a substance in the body that causes inflammation. Cimzia is available in a prefilled autoinjector and it simplifies the administration process.
Cimzia Autoinjector allows patients to manage treatment at home, which is especially beneficial for those with chronic conditions requiring long-term management. Regular use of Cimzia can reduce symptoms like joint pain and stiffness, improve physical function, and potentially decrease the necessity for additional medications.
What Is Cimzia Injection Used For?
- Non-radiographic axial spondyloarthritis
- Uveitis
- Psoriatic arthritis
- Ulcerative colitis
- Crohn’s disease
- Plaque psoriasis
- Rheumatoid arthritis
- Ankylosing spondylitis
What Are the Benefits of Cimzia Autoinjector?
- Helps reduce inflammation and slow disease progression in autoimmune conditions.
- Available in prefilled autoinjector format for easy, precise dosing.
- Reduces joint pain and stiffness in rheumatoid arthritis patients.
- May be effective for patients who have not responded to other treatments.
- Offers flexibility in dosing schedule based on individual patient needs.
- Potentially reduces the need for multiple medications.
- Helps control symptoms and prevent further joint damage in rheumatoid arthritis.
- Can be used in combination with other disease-modifying antirheumatic drugs (DMARDs).
- Clinically proven to provide significant symptom relief in various inflammatory conditions.
What Are the Most Common Side Effects of Cimzia?
Common Cimzia Autoinjector side effects may include:
- High Blood Pressure
- Joint Pain (in patients with Crohn’s disease)
- Rashes
- Herpes Infections
- Injection Site Reaction
- Upper Respiratory Infection such as common cold and flu
- Urinary Tract Infection
- Headache (in patients who have arthritis or psoriasis)
- Mild Allergic Reaction
[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
What Strengths Does Cimzia Come In?
Cimzia is available in the following forms and strength:
- Prefilled Syringe: 200 mg
- Single-Dose Vial: 200 mg
What Is the Typical Dosage of Cimzia Autoinjector?
Dosage for Plaque Psoriasis in Adults
- Standard Dosage: 400 mg (two 200 mg injections) every two weeks.
- Initial Treatment: Administer 400 mg at the start, another 400 mg two weeks later, and a third 400 mg dose four weeks after the first.
- Subsequent Treatment: After initial treatment, reduce to 200 mg every two weeks.
Dosage for Crohn’s Disease in Adults
- Initial Treatment: Start with 400 mg, followed by 400 mg doses two and four weeks later.
- Maintenance Treatment: If symptoms improve, continue with 400 mg every four weeks.
Dosage for Rheumatoid Arthritis and Psoriatic Arthritis in Adults
- Initial Treatment: 400 mg initially, another 400 mg two weeks later, and a third 400 mg dose four weeks from the start.
- Ongoing Maintenance Treatment: Choose either 200 mg every two weeks or 400 mg every four weeks, based on your doctor’s advice.
Dosage for Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis in Adults
- Initial Treatment: 400 mg initially, followed by 400 mg doses two and four weeks later.
- Maintenance Treatment: Either 200 mg every two weeks or 400 mg every four weeks as recommended.
How Do You Take Cimzia?
- Initial Administration:
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- Cimzia is typically first administered by a healthcare professional in a medical setting.
- You may also be trained on self-injection techniques using a prefilled syringe for home use.
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- Injection Technique:
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- Cimzia is administered subcutaneously, which means the injection is given just under the skin.
- Rotate injection sites to prevent skin thickening or lumpiness.
- Each syringe is for single use only to ensure sterility.
How to Inject Cimzia?
- Preparation:
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- Remove the syringe from the refrigerator and allow it to warm to room temperature for 15 to 20 minutes before injecting. Avoid using heat to warm it up.
- Ensure the medication is clear and particle-free. Do not use, if discolored or cloudy.
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- Injection Process:
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- Wash and dry your hands thoroughly.
- Clean the injection site with an alcohol swab and let it dry.
- Remove the needle cover and, holding a pinch of skin, insert the needle at a 45-degree angle.
- Inject the content slowly and steadily, then dispose of the needle safely in a sharps container.
- Place a cotton ball or gauze over the injection site briefly to stop any bleeding.
What to Do When You Miss a Dose of Cimzia Autoinjector?
- Contact your doctor if you miss an appointment for an injection.
- If self-injecting, take the missed dose as soon as you remember and adjust future injections as advised by your healthcare provider.
[Note: Do not take two doses of Cimzia Autoinjector at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]
What Happens When You Overdose on Cimzia Autoinjector?
- Strictly follow the prescribed dosage. Seek emergency medical attention if severe symptoms occur or an overdose is suspected.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Cimzia Autoinjector Work?
Cimzia targets conditions caused by an overactive immune system, such as Crohn’s disease, various forms of arthritis, and psoriasis. It works by blocking tumor necrosis factor (TNF), a protein that causes inflammation, helping to reduce symptoms associated with these diseases.
What Is the Most Important Information I Should Know About Cimzia?
- FDA Boxed Warnings:
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- Infections: Increases risk of serious infections like TB; requires testing before use.
- Cancer: May elevate the risk of cancers such as lymphoma and leukemia; monitor for skin changes.
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- Precautions:
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- Hepatitis B: Reactivation possible; requires prior testing.
- Heart Conditions: Could worsen heart failure.
- Neurological Issues: May exacerbate nerve-related disorders.
- Blood Cell Counts: Potential for lowering counts; monitor regularly.
- Allergies: Avoid known allergies to Cimzia or TNF blockers.
- Latex Sensitivity: Contains latex in the syringe cap.
- Pregnancy/Breastfeeding: Safety not established; minimal transfer in breast milk.
- Alcohol Interaction: Can increase side effects like headaches.
How Do You Store Cimzia Autoinjector?
- Keep Cimzia vials and prefilled syringes refrigerated at temperatures between 36°F and 46°F (2°C to 8°C).
- Unopened vials can be stored at room temperature for up to 6 months. Do not refrigerate again after storing at room temperature.
What Medications Cannot Be Taken with Cimzia?
- Interactions with Immunosuppressant Drugs:
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- Corticosteroids such as prednisone (Rayos)
- Otrexup (methotrexate)
- Rasuvo (methotrexate)
- Trexall (methotrexate)
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- Interactions with Live Vaccines:
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- Yellow fever
- Tuberculosis
- Chickenpox
- The nasal spray form of the flu vaccine
- Measles, rubella (MMR), and mumps
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- Interactions with Certain Other Biologics:
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- Tysabri (natalizumab)
- Kineret (anakinra)
- Orencia (abatacept)
- Rituxan (rituximab)
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]
What Is an Alternative to Cimzia?
- Enbrel (etanercept)
- Azasan (azathioprine)
- Simponi (golimumab)
- Rayos (prednisone)
- Xeljanz XR (tofacitinib)
- Purixan (6-mercaptopurine)
- Otezla (apremilast)
- Cosentyx (secukinumab)
- Naprosyn (naproxen)
- Rasuvo (methotrexate)
- Actemra (tocilizumab)
- Remicade (infliximab)
- Advil (ibuprofen)
- Simponi Aria (golimumab)
- Soriatane (acitretin)
- Ilumya (tildrakizumab)
- Otrexup (methotrexate)
- Orencia (abatacept)
- Imuran (azathioprine)
- Taltz (ixekizumab)
- Kineret (anakinra)
- Trexall (methotrexate)
- Humira (adalimumab)
- Stelara (ustekinumab)
[Note: Your healthcare provider will choose which Cimzia Autoinjector alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Cimzia Autoinjector Cost & Coupons
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Frequently Asked Questions
Can you do Cimzia at home?
Yes, you can administer Cimzia at home after receiving proper training from your healthcare provider on how to inject it correctly. Refresher training is also available if needed.
Is Cimzia hard on your liver?
Cimzia may cause liver inflammation, resembling symptoms of lupus. If you experience severe allergic reactions or symptoms like those of lupus, stop using Cimzia and contact your healthcare provider immediately.
Can you drink alcohol on Cimzia?
Alcohol does not interact directly with Cimzia, but it may intensify some side effects such as headaches. It’s best to discuss alcohol consumption with your doctor.
What to avoid while on Cimzia?
Avoid live vaccines while taking Cimzia, as these can pose health risks. Non-live vaccines like the flu shot are safe and recommended annually.
Where is the best place to inject Cimzia?
Cimzia should be injected under the skin in the abdomen or thigh, as directed by your healthcare provider.
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