Nicardipine Hydrochloride
Buy Cardene Online
Cardene capsules, FDA-approved for managing chest pain and hypertension, work by relaxing blood vessels to lower blood pressure and alleviate angina. This calcium channel blocker also influences heart rate, enhancing its effectiveness. Available in both brand and generic forms, Cardene comes in 20 mg, 30 mg, and 45 mg doses, with sustained-release options of 30mg, 45 mg, and 60 mg. So, if you want to buy Cardene online from Canada, you need a valid prescription from your doctor.
Product Overview
Cardene (nicardipine hydrochloride) is a calcium channel blocker used primarily to treat hypertension and angina. Relaxing the heart and blood vessel muscles helps lower blood pressure & improve blood flow, thus easing chest pain and reducing the risk of heart-related issues.
Administered in 20 mg, 30 mg, and 45 mg capsules, Cardene should be taken 2-4 times daily based on the seriousness of the condition and individual needs. It can be consumed with or without food, though food intake may affect drug absorption.
Common side effects of Cardene include headache, dizziness, nausea, & flushing, which typically lessen as the body adapts. Severe reactions like rapid heartbeat or significant swelling require immediate medical attention. Patients with heart or liver conditions should consult their doctor before use. You can buy Cardene online from a top Canadian pharmacy.
Uses of Cardene
- Cardene oral capsules are prescribed for treating stable angina, which is a serious chest pain due to reduced blood flow to the heart.
- Cardene assists in managing and regulating blood pressure levels.
Benefits of Cardene
- Blood Pressure Reduction
- Angina Treatment
- Prevention of Heart Complications
- Enhanced Cardiac Output
- Flexible Administration
Side Effects of Cardene
Common Cardene side effects may include:
- Dizziness
- Sweating
- Blurred vision
- Unusual tiredness or weakness
- Confusion
[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]
Cardene Dosage
Cardene medication is available in various forms and strengths as follows:
Forms & Strengths
Capsules
- 20 mg
- 30 mg
- 45 mg
Capsules Sustained-Release
- 30 mg
- 45 mg
- 60 mg
Infusion Solution
- 20 mg per 200 mL
- 40 mg per 200 mL
Injectable Solution
- 2.5 mg per mL
Recommended Dosage for Cardene
Dosage Instructions for Cardene Capsules
For Treating Chest Pain:
- Adults: Initially, take 20 mg three times daily. Based on your response, your doctor may adjust this dosage.
- Children: The use and dosage must be determined by a pediatrician.
For Managing High Blood Pressure:
- Adults: Start with 20 mg three times daily. Your doctor may modify the dose depending on your medical response.
- Children: A doctor should determine whether and how to use this medication.
Dosage Instructions for Cardene Sustained-Release Capsules
- Adults: Begin with 30 mg of Cardene SR administered twice daily. Remember that the dose should be individually adjusted based on the patient’s blood pressure response.
- Children: The usage and dosage should be prescribed by a pediatrician.
How to Take Cardene?
- Take Cardene capsules by mouth, usually three times a day, with or without food.
- Follow your doctor’s dosage instructions, which depend on your medical conditions and response to the medication.
- Your doctor may adjust your dosage over time; always follow their directions.
- For best results, take Cardene regularly at the same times each day.
- Continue taking Cardene even if you feel well, as high blood pressure often has no symptoms.
- Inform your doctor or healthcare provider if your condition does not improve or worsen (e.g., high blood pressure persists or increases or chest pain becomes more frequent or severe).
- Avoid skipping doses and do not stop taking the medication unless directed by your doctor.
- Regularly check the expiration date and do not use the medication if it has expired.
Missed Dose
If you forget to take a Cardene dose, don’t take stress. If you are near your next dose, just skip the missed Cardene dose and continue with your regular schedule. Don’t take a double Cardene dose to make up for the one you missed earlier on. Keep following your usual dosing times moving forward. To help you remember to take your medication, consider keeping a medication schedule or setting reminders.
[Note: Do not take two doses of Cardene at the same time to compensate for a missed dose. This can increase your chances of experiencing severe side effects.]
Overdose
If you think you’ve overdosed on Cardene, you might experience symptoms like very low blood pressure, a slow heart rate following an initial rapid heart rate, and changes in heart rhythm. It’s important to act quickly. Contact a poison control center or you can seek emergency medical help right away. If you’re in the US, you can reach out to your local poison control center for advice.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Cardene Work?
Nicardipine Hydrochloride, also known as Cardene, is a calcium channel blocker that helps relax and dilate blood vessels by blocking calcium ions from entering the smooth muscle cells. This action lowers blood pressure and alleviates chest pain, especially in angina where restricted blood flow limits oxygen to the heart. By improving blood flow, nicardipine hydrochloride benefits patients with cardiovascular issues.
Important Safety Precautions
- Use Cardene cautiously if you have impaired liver function, as it can affect drug metabolism and increase the risk of side effects. Regular monitoring & dosage adjustments may be necessary.
- Avoid using Cardene if you have certain heart conditions, like aortic stenosis or kidney disease. Discuss your full medical history with your doctor before starting this medication.
- Inform your doctor or dentist if you are taking Cardene before any surgery or dental procedure to manage potential interactions or complications.
- Cardene can cause dizziness, affecting activities like driving or operating machinery. Avoid these activities until you know how the medication affects you and limit alcohol intake.
- Use Cardene during pregnancy only if absolutely necessary and under medical advice. Consult your doctor if breastfeeding, as it’s unclear if Cardene passes into breast milk.
Storage
- Store Cardene in a closed container at room temperature (25°C).
- Protect the medication from excessive heat, moisture, and direct sunlight.
- Ensure Cardene does not freeze.
- Keep Cardene out of reach of children.
- Dispose of any expired or unused medication.
Cardene Interactions
- Beta-Blockers: Cardene is often used with beta-blockers and is generally well-tolerated. However, monitoring for adverse effects is necessary.
- Cimetidine: The use of cimetidine with Cardene increases plasma levels of Cardene, requiring close monitoring and potential dosage adjustments.
- Digoxin: Although Cardene does not typically affect digoxin levels, monitoring serum digoxin levels after initiating therapy is recommended.
- Fentanyl Anesthesia: There is a risk of severe hypotension during fentanyl anesthesia when used with beta-blockers and calcium channel blockers. Preparing an increased volume of circulating fluids during such procedures is advised.
- Cyclosporine: Cardene increases plasma levels of cyclosporine, necessitating close monitoring and dosage adjustments to avoid toxicity.
- Food/Tobacco/Alcohol: Avoid taking Cardene capsules near meal times, and concurrent use with alcohol or tobacco is discouraged due to potential interactions.
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]
Cardene Alternatives
- Tenormin (atenolol)
- Microzide (hydrochlorothiazide)
- Cozaar (losartan)
- Coreg (carvedilol)
- Lasix (furosemide)
- Prinivil (lisinopril)
- Toprol XL (metoprolol)
- Aldactone (spironolactone)
- Norvasc (amlodipine)
- Entresto (sacubitril and valsartan)
- Lisinopril (lisinopril)
[Note: Your healthcare provider will choose which Cardene alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
Is Cardene a vasodilator?
Yes, Cardene is a vasodilator. It has been shown to significantly reduce systemic vascular resistance, especially when administered intravenously. Studies indicate that the vasodilation effects, along with the accompanying decrease in blood pressure, are more pronounced in patients with hypertension compared to normotensive individuals. Additionally, you can buy Caredene online from the best Canadian pharmacies at affordable prices.
What type of CCB is Cardene?
Cardene, known by its generic name Nicardipine, is a second-generation dihydropyridine calcium channel blocker (CCB). It is highly selective for vascular smooth muscle, promoting vasodilation which reduces blood pressure and decreases afterload.
How does Cardene affect heart rate?
Cardene, with its active ingredient Nicardipine, can influence heart rate by causing an initial increase. This effect is often a response to a drop in blood pressure, which is a common outcome when blood vessels dilate after Cardene administration. The body may compensate for the lowered blood pressure by increasing the heart rate, a phenomenon known as reflex tachycardia.
Is nicardipine better tolerated than nifedipine?
Nicardipine is often considered better tolerated than nifedipine, primarily due to the nature of its effects on blood pressure. Nicardipine tends to lower blood pressure in a more gradual and sustained manner compared to nifedipine. This slower and more controlled reduction in blood pressure can be less shocking to the system, potentially resulting in fewer immediate side effects like severe drops in blood pressure or reflex tachycardia that can occur with more abrupt changes.
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