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Betahistine Dihydrochloride

Betahistine Tablets

Betahistine Tablet (betahistine dihydrochloride) is an FDA-approved medication to increase the flow of blood to the inner ear, alleviating the pressure caused by excess fluid accumulation. This pressure is believed to be responsible for the symptoms experienced by individuals with Ménière’s disease, including nausea, vertigo (dizziness), tinnitus (ringing in the ears), and hearing loss. By reducing this pressure, the medication helps to reduce the severity of these symptoms & decrease their frequency. While it may take a few weeks before noticeable improvements occur, it is important to continue taking the tablets as directed, even if symptoms improve, until your doctor advises otherwise. So, if you want to buy Betahistine tablets for Ménière’s disease, you need a prescription from your doctor.

Product Overview

Betahistine tablet is an FDA-approved medication used to prevent and treat Ménière’s disease, an inner ear disorder. Ménière’s disease is characterized by symptoms such as dizziness, tinnitus, nausea, and loss of hearing capabilities, often caused by an accumulation of fluid in the inner ear. This medication works by reducing the amount of fluid in the ear, thereby alleviating these symptoms.

It is important to take a Betahistine 16mg tablet as your doctor prescribes. The tablet should be swallowed whole with water and taken at the same time(s) each day to ensure the most benefit. Your doctor will determine the correct Betahistine dosage for you based on your symptoms and may recommend that you take the medication for several months. It is crucial to continue taking the medication for the duration prescribed by your doctor or healthcare giver, even if you start to feel better.

Like all medications, Betahistine 16mg tablets can cause side effects. The common side effects of Betahistine may include headache, nausea, and indigestion. Some people may also experience stomach pain and bloating. Taking medication with food can help reduce stomach-related side effects.

Before taking Betahistine 16mg tablets, it is important to inform your doctor if you have asthma, stomach ulcer, or high or low blood pressure. You should also tell your doctor about any other medications you are taking to ensure that there are no interactions. Additionally, if you are pregnant or breastfeeding, then you need to speak to your doctor before taking this medication.

Uses of Betahistine Tablets

  • Betahistine tablet is a medication prescribed for alleviating the symptoms associated with Ménière’s disease, which includes sensations of dizziness & vertigo, ringing in the ears, hearing loss, and nausea.

How to Use Betahistine Tablets?


Betahistine comes as oral tablets and has the following strengths:  

  • Betahistine 8mg tablets
  • Betahistine 16mg tablets
  • Betahistine 24mg tablets

Recommended Dosage for Different Patients

Initially dose: 8-16mg 3 times daily, preferably with foods.

Maintenance doses: These are generally within the range of 24-48mg daily.

The dosage should be tailored to individual needs, and improvement may only become evident after a few weeks of treatment.

[Note: Remember these recommendations, as mentioned above, can vary depending on person to person. You need to discuss it with your doctor or pharmacist, and they’ll customize your Betahistine tablets dosage accordingly.]

How to Take It?

  • Take half or one tablet three times a day.
  • If multiple tablets are prescribed daily, distribute them evenly throughout the day. For example, take one tablet in the morning, one at midday, and one in the evening.
  • Aim to take your tablet consistently at the same time daily.
  • Consistent timing ensures a steady presence of the medication in your body.
  • Swallow the tablets whole with water unless otherwise instructed. 
  • Avoid breaking or crushing tablets unless advised by your healthcare provider.
  • Establishing a routine helps in remembering to take your medication regularly.

[Note: Your doctor or pharmacist will decide the right Betahistine tablets amount for you based on your condition, following guidelines & studies on the drug. They’ll adjust it as needed over time.]

How Do Betahistine Tablets Work?

Betahistine tablet is a medication primarily used to treat Ménière’s disease, a condition characterized by episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. It works by mimicking the effects of the natural substance histamine, which plays a crucial role in the inner ear. Specifically, Betahistine tablets act as both an agonist (activator) and antagonist (blocker) at histamine receptors. It primarily targets the H1 receptors, enhancing blood flow within the inner ear, which helps to reduce the pressure from excess fluid (endolymphatic hydrops). Additionally, Betahistine tablets may also influence the vestibular nuclei in the brainstem, which helps to improve symptoms of vertigo by promoting more stable sensory processing and neural transmission related to balance. This dual action makes Betahistine tablets effective in alleviating the symptoms associated with Ménière’s disease.

Important Safety Information

Side Effects

Common side effects of Betahistine tablets include:

  • Swelling of the  lips, face, tongue, or neck
  • Drop in blood pressure
  • Difficulty breathing
  • Lack of alertness
  • Vomiting
  • Indigestion
  • Headache
  • Stomach pain
  • Abdominal distension

Mild side effects of Betahistine tablets include:

  • Tightness in the chest
  • Itching
  • Skin peeling

Serious side effects of Betahistine tablets include:

  • Wheezing
  • Hives

[Note: This list might not include all potential side effects. Consult your healthcare giver for medical advice regarding side effects.]


Use in Patients with Porphyria: Betahistine tablets should not be used in patients with porphyria, a group of disorders that result from a buildup of chemicals (natural) that produce porphyrin in the body. The use of Betahistine tablets in such patients can exacerbate the symptoms of porphyria and should be avoided.

Patients with Bronchial Asthma: These patients should use Betahistine tablets with caution. While Betahistine tablets are generally well-tolerated, they may exacerbate respiratory symptoms in patients with asthma. It is advisable to consult with a doctor or a healthcare professional before initiating treatment with Betahistine tablets in such cases.

Not Recommended for Children: Betahistine tablets are not recommended for use in children. The safety and efficacy of Betahistine tablets in pediatric patients have not been established, and their use in this population should be avoided unless specifically directed by a healthcare provider.

Avoid in Persons with Galactose Intolerance: Betahistine tablets should not be used in persons with galactose intolerance, a condition characterized by the inability of your body to metabolize galactose, a sugar found in milk & dairy products. Betahistine tablets contain lactose and should be avoided in individuals with galactose intolerance.

Potential Stomach Discomfort: Betahistine tablets may cause mild stomach discomfort in some patients. Taking Betahistine with food can help reduce the risk of stomach-related side effects. Patients experiencing persistent or severe stomach discomfort should consult with their healthcare provider.


Allergies: If you experience an allergic reaction to Betahistine tablets, discontinue use immediately and seek medical attention from a doctor or go to a hospital immediately. Signs of an allergic reaction may include:

  • A red or bumpy skin rash or itchy skin.
  • Swelling of the face, tongue, or neck
  • Decrease in blood pressure
  • Loss of consciousness
  • Difficulty breathing

Pheochromocytoma: Notify your healthcare provider if you have a rare adrenal gland tumor called pheochromocytoma.

Other Important Precautions 

Pregnancy and Breastfeeding: Pregnant or breastfeeding females should consult with their healthcare provider before taking Betahistine tablets. The use of Betahistine tablets during pregnancy and breastfeeding is only recommended when the potential advantages outweigh the possible risks to the infant or fetus. Healthcare providers can guide the appropriate use of Betahistine tablets in these situations.

Missed Dose

  • If you forget to take a dose, take this medication as soon as possible. 
  • However, if it is almost next time for your dose, skip the missed Betahistine dose and continue with your regular dosing schedule. 
  • Do not take a double dose to make up for a missed one.

[Note: Please consult your doctor or pharmacist immediately if you’ve missed a dose of your medication and are still determining when to take the next one.]


If you or someone takes an overdose of Betahistine tablets, you may experience nausea, drowsiness, or stomach pain. Seek medical assistance from a pharmacist or a doctor immediately.

[Note: If you’ve taken more than the recommended dosage, seek immediate medical assistance or contact the Poison Help line at 1-800-222-1222.]


  • Keep your tablets below 25°C. Store them in their original package. 
  • Do not store in humid places such as the bathroom or freezer compartment. 
  • Don’t use tablets after the expiry date printed on the pack. 
  • Keep medicines away from kids.
  • Return any leftover tablets to the pharmacy for safe disposal.
  • If tablets look weird or damaged, ask your pharmacist for advice.

[Note: Consult your healthcare provider regarding the appropriate disposal of any unused medication and for any queries concerning its storage.]

Betahistine Tablets Interactions

Acrivastine: When Betahistine tablets are taken in combination with Acrivastine, the therapeutic efficacy of this medication may be reduced. 

Albuterol: When Betahistine tablets are used alongside Salbutamol, also known as Albuterol, the therapeutic efficacy of Salbutamol may be diminished. This interaction could lessen the intended benefits of Salbutamol.

Alimemazine: The combination of Betahistine and Alimemazine can reduce the efficacy of this medication. 

Amitriptyline: When Betahistine tablets are used in conjunction with Amitriptyline, the therapeutic efficacy may be decreased. 

Amoxapine: The combination of Betahistine tablets with Amoxapine can reduce their therapeutic efficacy. 

[Note: This list might not include all potential interactions, as other medications could interact with Betahistine. It’s crucial to adhere closely to your doctor’s guidance and ensure you have your medication for sudden asthma symptoms.]

Betahistine Tablets Alternatives

  • Histidiz (betahistine)
  • Dizibeat (betahistine)
  • Betanil (betahistine)
  • Vertiford (betahistine)
  • Zevert (betahistine)
  • Wertilin (betahistine)
  • Biohistin
  • Vertin (betahistine)
  • Vertistar (betahistine)
  • Neuvert (betahistine)
  • Bvert
  • Vertirest (betahistine)
  • Vesbal 
  • Vernil (betahistine)

[Note: Your doctor will choose the best option tailored to your needs. Make sure to consult your healthcare provider before exploring any alternative medications, as using them without professional guidance could result in serious side effects.] 

Frequently Asked Questions

How many Betahistine tablets can I take in a day?

Betahistine begins with a dosage of 16mg taken three times a day. It is essential to space these doses out evenly, ideally leaving 6 to 8 hours between each intake. This ensures the medication maintains its effectiveness throughout the day. Once your symptoms are better managed, your doctor might adjust your dosage. In many cases, this reduction involves shifting to an 8mg dose, still taken three times daily. Always follow your doctor’s guidance regarding dosage adjustments, as they tailor the treatment to your specific needs, ensuring optimal control of symptoms with minimal side effects.

Do Betahistine tablets lower blood pressure?

Betahistine, primarily used for treating vertigo and Meniere’s disease, can sometimes cause a decrease in blood pressure, known as hypotension. This drop in blood pressure may be accompanied by other side effects, such as an accelerated heartbeat, a condition called tachycardia, and difficulty breathing due to bronchospasm, which involves a feeling of suffocation. Fluid retention, leading to swelling or edema, can also occur. It’s important to note that very high doses of Betahistine might trigger seizures. Therefore, it is crucial to follow prescribed dosages and monitor any unusual symptoms closely.

Can I take Betahistine tablets with high blood pressure?

It’s important to know that Betahistine may not be suitable for everyone, especially if you have certain health conditions. If you have high blood pressure due to an adrenal tumor, it’s crucial to inform your doctor or pharmacist before using Betahistine. This medication can also trigger allergic reactions, so if you’ve ever had an adverse response to Betahistine or any other medicine, share this information with your healthcare provider. Always be transparent about your medical history to ensure that Betahistine is safe and appropriate for you.

Can Betahistine tablets make you sleepy?

Yes, Betahistine can cause drowsiness or fatigue in some individuals. These side effects, such as dizziness and tiredness, can impair your ability to work that needs alertness, like driving or operating heavy machinery. If you experience any of these symptoms, avoiding engaging in activities that could put you or others at risk is crucial. Moreover, exercise caution when consuming alcohol while taking this medication, as alcohol may amplify these side effects. It’s essential to be mindful of how this medicine affects you and take appropriate precautions to ensure your safety.

Is it safe to take Betahistine and Cetirizine together?

Generally, it’s not advisable to take Cetirizine and Betahistine simultaneously. Cetirizine, an antihistamine, can interfere with the effectiveness of betahistine, which is commonly used to treat Ménière’s disease. The interaction between these two medications might diminish the therapeutic benefits of Betahistine, rendering it less effective in managing your symptoms. Therefore, it is recommended to avoid using them in combination. It’s crucial to consult your healthcare giver before combining medications to ensure they do not negatively interact and to determine the best treatment approach for your condition.

Are Betahistine tablets good for anxiety?

While Betahistine tablets are often used to treat vertigo and related conditions, their effectiveness for anxiety remains unclear. A study investigating the combination of betahistine and the Epley maneuver, a common treatment for benign paroxysmal positional vertigo (BPPV), found no significant change in anxiety levels. The study compared pre-treatment and post-treatment scores on the Beck Anxiety Inventory (BAI) and found that adding betahistine to the Epley maneuver did not significantly affect anxiety in BPPV patients. This suggests that Betahistine tablets may not have a notable impact on anxiety, particularly in the context of BPPV treatment.

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