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Benzoyl Peroxide, Clindamycin (Clindamycin Phosphate)

Benzaclin Topical Gel

Benzaclin Topical Gel is FDA-approved for acne. It combines Benzoyl Peroxide and Clindamycin to combat bacteria and reduce inflammation in pimples and blackheads. Follow your doctor’s guidance to apply it once or twice daily in affected areas. Suitable for those over 12 with moderate to severe acne, it comes in strengths ranging from 2.5% to 5% Benzoyl Peroxide and 1% Clindamycin. Side effects like dryness and redness are common but usually temporary. If you miss a dose, apply it when you remember, but skip it if it’s almost time for the next one. Overdose is unlikely, but if ingested, seek medical help. Keep it at room temperature, distant from dampness and heat, and remember sunscreen as it increases sun sensitivity.

Product Overview

Benzaclin Topical Gel is a treatment approved by the FDA for acne. It has two main ingredients: Benzoyl Peroxide and Clindamycin. These help kill bacteria and reduce inflammation in pimples and blackheads. You apply the gel to your skin where you have acne, usually once or twice a day. It works best for people over 12 with moderate to severe acne.

The gel has different strengths, with Benzoyl Peroxide ranging from 2.5% to 5% and Clindamycin at 1%. You just put it directly on your skin, following the instructions from your doctor. While using it, you might experience dryness, redness, or peeling, but don’t worry; these are common and usually go away with time. Just be careful not to get it in your eyes or mouth.

If you forget to apply it, put it on as soon as you remember. But if it’s almost time for your next dose, skip the one you missed. Overdosing isn’t a concern with this gel, but if you accidentally swallow it, seek medical help. Keep it at room temperature, away from moisture and heat, and remember to wear sunscreen as it makes your skin more vulnerable to sunburns. You should always follow the instructions given by your healthcare practitioner regarding the safe and effective use of Benzaclin Topical Gel.

Uses of Benzaclin Topical Gel

  • It is used to treat acne.

How to Use Benzaclin Topical Gel?


Strengths and Forms

Form: Topical Gel

Strengths: 2.5% to 5% Benzoyl Peroxide and 1% Clindamycin

Recommended Dosage of Benzaclin Topical Gel

  • Once the skin is gently cleansed and rubbed dry with lukewarm water, apply BenzaClin Topical Gel twice daily or as your healthcare professional directs you to.

[Note: These Benzaclin Topical Gel dosage recommendations may differ from individual to individual. Discuss it with your healthcare professional, and they’ll decide your dosage accordingly.]

How to Take It?

Here are the instructions to apply Benzaclin Topical Gel:

  • Ensure the affected location is clean and dry before using.
  • Dispense a small amount of gel, equivalent to the size of a pea.
  • Apply a thin gel layer gently onto the affected skin, covering it entirely.
  • Avoid getting it into your eyes, nose, mouth, or mucous membranes.
  • After application, properly wash your hands to prevent spreading the gel accidentally.
  • Let the gel air dry completely before applying other skincare products or makeup.
  • Use Benzaclin Topical Gel per your doctor’s instructions, typically once or twice daily.
  • Even if you notice improvement, continue using the gel for the recommended duration.

[Note: Your healthcare professional will decide the correct amount of Benzaclin Topical Gel for you based on your condition. They may adjust your Benzaclin Topical Gel dosage as needed over time.]

How Does Benzaclin Topical Gel Work?

Benzaclin Topical Gel combines Benzoyl Peroxide and Clindamycin to treat acne effectively. Benzoyl peroxide is an antimicrobial agent, killing acne-causing bacteria on the skin’s surface. Clindamycin, an antibiotic, reduces inflammation associated with acne lesions. Together, these ingredients target the bacteria and inflammation involved in acne development. By addressing multiple factors contributing to acne, Benzaclin Topical Gel helps clear existing blemishes and prevent new ones from forming, promoting clearer, healthier skin.

Important Safety Information

Side Effects

Common side effects of Benzaclin Topical Gel may include:

  • Dryness or peeling of the skin
  • Redness or irritation at the application site
  • Mild burning or stinging sensation

Mild side effects of Benzaclin Topical Gel may include:

  • Itching or discomfort on the skin
  • Temporary changes in skin color
  • Sensitivity to sunlight

Adverse side effects of Benzaclin Topical Gel may include:

  • Severe skin irritation or blistering
  • Allergic reactions such as rash or swelling
  • Excessive dryness or flaking of the skin
  • Worsening of acne symptoms

[Note: This list may not cover all possible Benzaclin Topical Gel side effects. Always discuss with your healthcare giver for medical advice about side effects.]


Allergic Reactions: If you have known allergies to benzoyl peroxide, Clindamycin, or any other ingredients in Benzaclin, avoid using it. Allergic reactions may include irritation, redness, itching, inflammation, or problem breathing. If any of the symptoms occur, you should seek immediate medical attention.

Avoid Contact with Eyes and Mucous Membranes: Benzaclin is for external use only. Avoid getting it in your eyes, mouth, nose, or other mucous membranes. If it happens, rinse thoroughly with water and seek medical advice if irritation persists.

Sun Sensitivity: Benzaclin may increase sensitivity to sunlight. Limit sun exposure and use sunscreen while using the gel to decrease the risk of sunburn and skin irritation.

Avoid Use on Broken Skin: Do not apply Benzaclin to open wounds, cuts, or broken skin, as it may cause excessive irritation or systemic absorption, leading to adverse effects.

Pregnancy and Breastfeeding: The safety of Benzaclin during pregnancy and breastfeeding has not been established. Consult your healthcare provider before using Benzaclin if pregnant or breastfeeding.

Avoid Excessive Use: Do not apply Benzaclin more frequently or in larger amounts than directed by your healthcare professional, as it may increase the risk of side effects without improving efficacy.


  • Cleanse your skin properly using a mild cleanser and pat it dry before applying Benzaclin Topical Gel.
  • Avoid using harsh, chemical-made skincare products that may irritate your skin before or during treatment with Benzaclin.
  • If you have sensitive skin or a history of skin irritation, perform a patch test by applying a small amount of the gel to a small area of the skin to watch for any adverse side effects before applying it to larger areas.
  • Apply a thin layer of Benzaclin Topical Gel only to the affected areas of your skin as directed by your healthcare provider. Avoid applying it to unaffected areas to minimize the risk of irritation.
  • Be cautious to avoid contact with your eyes, mouth, nose, and other mucous membranes while applying the gel. If it happens accidentally, rinse thoroughly with water.
  • Use sunscreen and wear full clothing to minimize sun exposure while using Benzaclin Topical Gel, as it may increase sensitivity to sunlight and the risk of sunburn.
  • After applying Benzaclin Topical Gel, wash your hands thoroughly to remove any residue and prevent unintentional transfer to other body areas.
  • Allow the gel to dry properly before applying other skincare products or makeup to avoid interference with its efficacy or potential irritation.
  • If you experience excessive dryness, redness, or skin irritation after applying Benzaclin Topical Gel, consult your healthcare provider for advice on adjusting your skincare routine or treatment regimen.

Benzaclin Topical Gel Contraindications

It is contraindicated:

  • In people who are hypersensitive to any of its components or Lincomycin.
  •  If you have a history of ulcerative colitis, regional enteritis, or antibiotic-associated colitis.

Missed Dose

  • If you forget a dose, use it as soon as you recall. But if it’s nearly time for your next dose, skip the missed one.
  • Don’t apply extra gel to compensate for a missed dose.
  • Using more than directed won’t enhance effectiveness and may heighten side effects.
  • Stick to the prescribed dosage to maintain safety and effectiveness.

[Note: If you have missed a dose of Benzaclin Topical Gel and are still deciding when to take the next dose, immediately consult your doctor or pharmacist.]


Do not use more Benzaclin than prescribed. Symptoms may include severe skin irritation or blistering.

[Note: If you overdosed on Benzaclin Topical Gel, get medical help instantly or call the Poison Help line at 1-800-222-1222.]


  • Keep Benzaclin Topical Gel at room temperature, distant from dampness and heat.
  • Keep it out of reach of children and pets.
  • Avoid exposing it to direct sunlight.
  • Avoid freezing the gel.
  • Keep the container tightly closed when not in use.

[Note: Consult with your healthcare practitioner about properly disposing of unused Benzaclin Topical Gel and any questions you may have regarding their storage.]

Benzaclin Topical Gel Interactions

Here’s a list of drugs known to interact with Benzaclin Topical Gel:

  • BCG vaccine
  • Erythromycin
  • Neuromuscular blocking agents (tubocurarine, pancuronium)
  • Other acne medications (dapsone)
  • Sulphonamides (topical)
  • Tazarotene

[Note: This list is incomplete, and Benzaclin Topical Gel may interact with other drugs. If you take prescription, over-the-counter, or herbal medicines, tell your doctor about them.]

Benzaclin Topical Gel Alternatives

Here are some alternatives to Benzaclin Topical Gel:

  • Acanya (clindamycin topical / benzoyl peroxide)
  • Doxycycline (doxycycline)
  • Spironolactone (spironolactone)
  • Onexton (benzoyl peroxide/clindamycin)
  • Duac Gel (benzoyl peroxide/clindamycin)
  • Neuac (benzoyl peroxide/clindamycin)
  • Z-Clinz 10 (benzoyl peroxide/clindamycin)
  • Acticlate (doxycycline)
  • Adoxa (doxycycline)
  • Adoxa CK (doxycycline)
  • Adoxa Pak (doxycycline)
  • Adoxa TT (doxycycline)

[Note: Your healthcare professional will select the best Benzaclin Topical Gel alternative. You should discuss your healthcare provider before using these alternative medications. You may experience serious side effects if you take them alone.]

Frequently Asked Questions

How long does Benzaclin Topical Gel take to work?

Benzaclin Topical Gel typically takes several weeks to show noticeable improvement in acne symptoms. However, individual responses may vary. Following your healthcare provider’s instructions and being patient during treatment is essential. Consult your doctor promptly if you have any concerns or experience adverse effects.

How often should I apply Benzaclin Gel?

Benzaclin Gel should be applied twice daily. Wash your face, apply a thin layer to affected areas, and allow it to dry before using other skincare products or makeup. Consistency is key to the best results. Consult your doctor if you experience any irritation or adverse effects.

How do I use Benzaclin Gel with other acne treatments?

If you’re using other topical acne treatments (such as retinoids or salicylic acid), apply them at different times of the day. For example:

  • Apply Benzaclin in the morning.
  • Use other topicals (if prescribed) in the evening.

Follow your doctor’s instructions if you’re taking oral antibiotics for acne. Benzaclin can complement oral antibiotics by targeting acne bacteria on the skin’s surface. Remember, individual responses may vary, so it’s essential to customize your skincare regimen to your individual needs. 

Can I apply Benzaclin Gel during pregnancy?

Benzaclin Topical Gel has not been extensively studied in pregnant women. While animal studies have not shown evidence of teratogenicity, there is no controlled human data. It falls under US FDA pregnancy category C, meaning potential risks exist, but benefits may outweigh them. Consult your healthcare practitioner before using it during pregnancy.

Our Guarantee

At, we assure you the most affordable price when you buy Benzaclin Topical Gel online from Canada. Rest easy knowing that your order will be dispatched from a reputable Licensed Canada Pharmacy Online, adhering to the highest standards of quality and authenticity. Our discounted medications are shipped directly from Canada to your doorstep, ensuring a swift and secure delivery experience. To conveniently access Benzaclin Topical Gel online at a substantial cost, call us at 1-888-779-2193 toll-free.


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