Baclofen

Buy Baclofen Tablets Online

Baclofen is an FDA-approved medication that helps ease muscle spasms from conditions like multiple sclerosis and spinal cord injuries. Baclofen works like the natural chemical GABA to lessen muscle tightness and improve movement. You can take these tablets several times a day, with or without food. They’re good for adults and children over 12, helping to relieve discomfort from neurological issues. Some common side effects are dizziness and feeling sleepy, so be careful when doing things that need you to be alert. So, if you want to buy Baclofen to treat muscle symptoms, you need to get a prescription from your doctor.

Product Overview 

Baclofen is an FDA-approved drug mainly used to ease muscle spasms from multiple sclerosis, spinal cord injuries, and other neurological conditions. These issues can cause severe muscle stiffness and pain, interfering with everyday activities. Baclofen works by mimicking gamma-aminobutyric acid (GABA), a neurotransmitter that reduces muscle spasticity, thereby easing muscle tightness and improving movement and comfort.

It’s taken several times a day, with or without food, and should be swallowed whole with water. Suitable for adults and children aged 12 and above, Baclofen is especially helpful for those who need regular control of muscle spasms. Common side effects of Baclofen include dizziness, headaches, drowsiness, nausea, and fatigue. 

These are usually mild, but if they persist or worsen, consulting a healthcare professional is important. Patients should avoid tasks requiring alertness, like driving, until they know how Baclofen affects them. If a dose is missed, take it as soon as possible unless it’s almost time for the next dose. For overdoses, seek immediate medical help. Store the medication at room temperature, away from light and moisture, and keep it out of reach of children and pets. Follow your doctor’s instructions carefully regarding dosage and discuss any concerns for safe and effective use.

Uses of Baclofen

Baclofen is a medication primarily used to treat muscle spasticity. Here are some of its main uses: 

• Spasticity Management
• Muscle Relaxation
• Symptom Relief in Neurological Diseases

Benefits of Baclofen

• It improves muscle functioning.

Side Effects of Baclofen

Common side effects of Baclofen may include:

• Nausea
• Headache
• Sweating
• Trouble sleeping
• Increased need to urinate
• Dizziness
• Constipation
• Drowsiness
• Unusual tiredness or weakness

[Note: This list is not exhaustive, if you notice any other symptoms that are not mentioned above, consult your doctor immediately.]

Baclofen Dosage

Forms & Strengths

Baclofen comes in the following forms & strengths:

• Tablets: 5 mg, 10 mg, 20 mg 
• Oral Solution: 5 mg per 5 mL 

Recommended Dosages

For Adults with Muscle Spasticity

Start with 5 mg three times daily.

• Gradually increase the dose by 5 mg every three days until the desired effect is reached.
• Typical maintenance dose: 40-80 mg per day, split into three or four doses.
• The maximum dose generally should not exceed 80 mg daily.

For Children with Muscle Spasticity (Ages 12 and Up)

• Begin with a dose of 2.5 mg three times daily.
• Doses can be slowly increased as necessary and tolerated, but generally should not exceed 40 mg daily.

For Patients with Renal Impairment

• Reduced doses or less frequent dosing may be necessary since Baclofen is primarily excreted by the kidneys.

For Patients Undergoing Hemodialysis

• Special dosing adjustments are required, considering Baclofen is dialyzable. Dose modifications may depend on the dialysis schedule.

How to Take Baclofen?

• Follow your doctor’s instructions precisely when taking Baclofen tablets. Usually, the initial dose is lower, and your doctor will guide you on any necessary adjustments.
• Baclofen should be taken three times a day, evenly spaced out, as your healthcare provider recommends.
• You may take 10 or 20 mg of Baclofen tablets with or without food. If you experience stomach upset, consuming the tablets with food may help alleviate discomfort.
• Swallow the tablet whole with water. Do not chew, crush, or split the tablet.
• To maintain a consistent level of medication in your bloodstream, take Baclofen at the same time each day.
• Keep taking Baclofen suddenly with your doctor’s advice, as this could lead to withdrawal symptoms. If discontinuation is necessary, your doctor will generally reduce your dose gradually.

Missed Dose

If you miss a dose of Baclofen, it’s important to take it as soon as you realize you’ve skipped it. However, if the time is close to when your next scheduled dose should be taken, it’s advisable to skip the missed dose entirely. Continuing with your regular dosing schedule without taking the missed dose will help maintain the medication’s effectiveness and avoid any potential overdose from doubling up doses.

[Note: Do not take two doses of Baclofen at the same time to compensate for a missed dose. This can increase your risk of experiencing side effects.]

Overdose

Symptoms of a Baclofen overdose may present as significantly increased drowsiness and heightened dizziness, which can escalate to extreme sleepiness. Individuals may find it difficult to concentrate or focus on objects, experiencing blurred or unstable vision. Respiratory issues such as shallow or slow breathing may occur. In more severe cases, symptoms can include seizures, potentially leading to a loss of consciousness or an inability to respond. These signs indicate a critical condition requiring immediate medical attention.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Baclofen Work?

Baclofen is used to ease muscle stiffness in conditions like multiple sclerosis and spinal injuries. It works as a muscle relaxant by affecting the central nervous system. Baclofen mimics GABA, a neurotransmitter that relaxes muscles, by activating GABA receptors. This action helps reduce muscle spasms and stiffness, improving movement and decreasing pain. As a result, it enhances life quality for those with muscle spasticity. 

Important Safety Precautions 

• Baclofen might increase the risk of ovarian cysts; discuss risks with your doctor.
• Inform your healthcare provider if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.
• Using Baclofen during pregnancy or breastfeeding may cause withdrawal symptoms in the baby, such as stiff muscles, tremors, or seizures.
• Tell your doctor if you have a history of:
  • Balance issues
  • Schizophrenia or confusion
  • High blood pressure or rapid heart rate
  • Stroke or blood clots
  • Kidney disease
  • Mental illness or psychosis
  • Cerebral palsy
  • Epilepsy or seizures
  • Parkinson’s disease
  • Rheumatic disease
• Do not take Baclofen if you are allergic to it.

Storage 

• Store the tablets at room temperature, between 68°F and 77°F.
• Keep in a dry location away from direct light.
• Maintain the medication in its original container with the lid tightly sealed to prevent air exposure.
• Keep children and pets out of reach to prevent accidental ingestion.
• Do not dispose of medications in the toilet or drain unless directed by the packaging or your pharmacist.

Baclofen Interactions 

• Muscle Relaxants: Combining Baclofen with other muscle relaxants can intensify their effects, heightening the risk of muscle weakness and respiratory complications.
• Central Nervous System Depressants: Using Baclofen alongside CNS depressants like benzodiazepines, tricyclic antidepressants, or alcohol can significantly increase the risk of respiratory depression, profound sedation, and dizziness.
• Diabetes Medications: Baclofen may raise blood glucose levels, potentially reducing the effectiveness of diabetes medications.
• Antihypertensive Drugs: Baclofen can amplify the effects of antihypertensive agents, leading to an elevated risk of hypotension.
• Monoamine Oxidase Inhibitors (MAOIs): The risk of hypotension and central nervous system depression may increase when Baclofen is taken with MAOIs.
• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): The interaction of Baclofen with NSAIDs may heighten the risk of kidney issues.
• Lithium: Simultaneous use of Baclofen and lithium might elevate the risk of lithium toxicity.

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions or supplements.]

Baclofen Alternatives 

• Norflex (orphenadrine)
• Skelaxin (metaxalone)
• Robaxin (methocarbamol)
• Zanaflex (tizanidine)
• Soma (carisoprodol)
• Lioresal (Baclofen – another brand)
• Flexeril (cyclobenzaprine)

[Note: Your healthcare provider will choose which Baclofen alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

Is Baclofen a pain reliever?

Yes, Baclofen alleviates the pain and discomfort associated with muscle spasms.

Is Baclofen safe daily?

Taking Baclofen daily for an extended period is generally safe. However, if you’ve been using it long-term, don’t stop abruptly without consulting your doctor. Generally, to minimize potential side effects, your doctor will taper your dosage gradually over a few weeks.

Is Baclofen bad for your kidneys?

Baclofen, a muscle relaxant frequently prescribed, is mainly eliminated through the kidneys. In patients with impaired kidney function, there is a significant risk of toxicity.

Does Baclofen affect BP?

While Baclofen primarily causes side effects like excessive sleepiness, dizziness, and confusion, it can also lead to more severe issues such as difficulty breathing and low blood pressure in extreme cases. It is important to consult your healthcare provider or pharmacist before beginning any new medication.

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