Oxipurinol
Buy Allopurinol Online at Affordable Price
Allopurinol is available as a generic and brand-name drug. Marketed under the brand names Lopuring and Zyloprim, this drug is used for the treatment of gout and kidney stones. Besides, it is also used for the prevention of increased uric acid levels in people undergoing cancer chemotherapy. The medication is available in an oral tablet form but can also be given to patients as an injection administered by a professional. The dosage can vary based on the patient’s condition.
Product Overview
Allopurinol is a prescription medication primarily used to treat gout and kidney stones. It contains the active ingredient oxipurinol, which lowers the production of uric acid in the body. Excessive uric acid can lead to painful gout attacks and the formation of kidney stones.
Available in strengths of 100 and 300 mg, Allopurinol should be taken exactly as prescribed by your healthcare provider, typically once a day after a meal. It is suitable for adults and children, depending on the condition being treated. Allopurinol helps manage these conditions effectively by restricting xanthine oxidase that are involved in the production of uric acid.
There are certain side effects of this medication which may include, rash, nausea, and diarrhea. Do not forget to inform your doctor about any allergies, medical history, or current medications. If you miss a dose, take it immediately, but avoid doubling up. In case of overdose, seek emergency medical assistance. Store the medication at room temperature, away from moisture and heat, and always follow your healthcare provider’s guidance for optimal results and safety.
Uses of Allopurinol
It is used to treat:
- Gout (a type of arthritis)
- Increased uric acid levels
- Certain types of kidney stones
Benefits of Allopurinol
- It helps minimize uric acid levels in the blood, which is crucial for managing conditions like gout and kidney stones.
- It prevents the formation of uric and crystals, thus reducing painful gout attacks.
- It is effective for long-term use.
- It helps lower the risk of kidney stone formation, especially uric acid stones.
Side Effects of Allopurinol
Common side effects of Allopurinol may include:
- Increased gout attacks at the beginning of the treatment
- Rash
- Nausea
- Vomiting
- Diarrhea
- Abnormal liver tests
- Drowsiness
- Swelling
- Troubled breathing
- Feeling tired
- Less urination
- Bruising
- Fever
- Headache
- Abdomen pain
- Joint pain
- Nosebleeds
- Taste changes
[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]
Allopurinol Dosage
Forms & Strengths
It comes in the following forms and strengths:
- Tablet: 100 mg and 300 mg
- Solution for Intravenous Injection: 20 mg/mL
Recommended Dosages
Dosage for Gout
- Starting Dose: Take 100 mg each day. If needed, the doctor may increase the dosage later.
- Standard Dose: 200-600 mg each day. This dose can be taken as a single tablet or divided into two or four doses.
Dosage for Hyperuricemia Due to Chemotherapy
- Standard Dose: Take 200-400 mg daily per square meter of the body’s surface area. You can take it as a single infusion or divide it into equal infusions every 6, 8, or 12 hours.
- Maximum Dose: 600 mg per day.
Dosage for Recurrent Calcium Oxalate Calculi
- Standard Dose: Take a single dose of 200 to 300 mg daily or divide it into two or three doses.
Children’s Dosage for Hyperuricemia Caused By Chemotherapy (2 Years & Above)
- Standard Dose: 300 mg daily per square meter of the body surface. You can divide it into two or four doses.
- Maximum Dose for Children Aged 11 Years & Above: 800 mg daily. Do not exceed 300 mg.
- Maximum Dose for Children Aged 6 to 10 Years: 300 mg daily.
- Maximum Dose for Children Aged 2 to 6 Years: 150 mg daily.
How to Take Allopurinol?
- Take the medicines as instructed by your healthcare provider.
- Take the medication after having your meals to avoid an upset stomach.
- Drink a lot of fluid while taking your tablets. This helps in preventing kidney stones.
- Ask your doctor about fluid intake for each day.
- If your dose exceeds 300 mg daily, take smaller doses of the medicine during the daytime.
- Take your medications simultaneously each day to get the most benefit.
- Try to swallow your tablets as a whole.
- If you are facing difficulty swallowing the tablets, either discuss the matter with your doctor, or you can break or crush them.
Missed Dose
- Take your medicines as soon as you remember.
- If it is almost time for your next dose, you can omit the missed one and resume your regular dosing plan.
- Try not to skip any doses, as it can cause adverse reactions.
- Use medication apps or set reminders on your phone to avoid skipping doses.
- You can talk with a medical expert if you have any concerns about your missed dose.
[Note: Do not take two doses of Allopurinol simultaneously to compensate for a missed dose. This can increase your risk of experiencing side effects.]
Overdose
If the drug level in your body exceeds the maximum amount, you are likely to experience serious side effects. This may include:
- Diarrhea
- Nausea
- Skin rash
- Gout flare-up
- Fluctuations in your liver function tests
If you notice any of the above symptoms, immediately get medical help or call 911.
[Note: If you notice you have taken too much medication, call your local emergency number immediately.]
How Does Allopurinol Work?
Every medication belongs to a certain class of drugs, meaning a group of medications that works similarly. Allopurinol oral tablets belong to the xanthine oxidase inhibitors class of drugs that help form uric acid. When a person takes Allopurinol tablets or injections, this drug blocks xanthine oxidase, thus reducing the uric acid levels in the blood & urine. Increased uric acid levels in blood or urine cause gout, kidney stones, and arthritis in a patient’s body. Therefore, doctors prescribe this medication to manage uric acid production in the body effectively.
Important Safety Precautions
- If you have a history of recurrent kidney stones, reduce your intake of animal protein, refined sugars, sodium, oxalate, and calcium-rich foods.
- Do not take this medication if you have allergies to Allopurinol ingredients.
- These oral tablets can cause liver problems as a side effect. So, if you have liver damage or had one in the past, the drug can exacerbate the condition. Talk to your medical practitioner before using the medication.
- Similarly, Allopurinol can also worsen your kidney problems, and there are chances that your kidney may not remove the drug properly, causing adverse effects on the system. Consult with a medical professional before taking this drug.
- Do not use this product if you are pregnant, as it may cause harm to the fetus, increasing the chances of birth defects. Although it is observed in pregnant animals, precautions must taken. Discuss with your doctor before making any decision.
- When using Allopurinol, breastfeeding is not advised as the medication may harm the child if it enters the breast milk.
Storage
- Store Allopurinol tablets at a room temperature of 20°C to 25°C.
- Keep it in a tightly closed container.
- Avoid keeping them damp in areas like the bathrooms or near the sinks.
- Keep them out of reach and sight of children.
- Do not flush the tablets or containers down the toilet.
- Discard medicines that are expired or not in use.
- Take professional advice on how you should dispose of medicines.
Allopurinol Interactions
- Ampicillin
- Hydrochlorothiazide
- Mercaptopurine
- Azathioprine
- Cyclosporine
- Chlorpropamide
- Warfarin
- Coumadin
- Jantoven
[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]
Allopurinol Alternatives
- Aloprim
- Febuxostat
- Probenecid
- Krystexxa
- Pegloticase
- Rilonacept
[Note: Your healthcare provider will choose which Allopurinol alternative is best for you. Taking or consuming them by yourself may cause serious side effects.]
Frequently Asked Questions
Can I gain weight while using Allopurinol?
No, you don’t gain weight by using Allopurinol oral tablets; rather, it causes weight loss in some patients as a side effect. The medication makes you feel less hungry; thus, it helps you lose weight. However, it is not advised to use Allopurinol as a weight loss medication; discuss it with your doctors once.
Do different strengths of Allopurinol have different side effects?
No, you won’t experience different side effects from the different strengths of the medication. However, you may likely notice increased side effects with a higher dose of Allopurinol. Some of the common side effects of the medication include joint pain, skin rash, drowsiness, etc.
How many days does Allopurinol take to start working?
Allopurinol generally takes 2 to 3 days to start working, but the days can vary depending on the individual’s reaction to the medication. Additionally, your doctor will prescribe a low dosage followed by an increasing dose. This variation in dosage might increase the days to 1 to 3 weeks to lower uric acid levels.
Can I drink alcohol while taking Allopurinol?
While there are no interactions between Allopurinol and alcohol, it is usually advised to avoid alcohol intake with this medication, as alcoholic beverages can increase uric acid levels, causing gout flare-ups. Therefore, it is important to limit your alcohol consumption or consult with a doctor for expert guidance.
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