(Fluticasone / Salmeterol)

Buy Advair Online 

Advair is a dual-action inhaler that combines fluticasone, a corticosteroid that reduces inflammation, with salmeterol, a beta-agonist that opens airways. It is essential for managing asthma and COPD. Designed for regular use, Advair improves lung function and decreases flare-ups when used twice daily. It’s crucial for ongoing symptom management but not for acute relief. Common side effects include sore throats and respiratory infections. Regular mouth rinsing after use is recommended.

Product Overview 

Advair is a prescription medication expertly designed to manage two primary respiratory conditions: asthma and Chronic Obstructive Pulmonary Disease (COPD). This inhaler combines fluticasone, a corticosteroid that reduces inflammation within the airways, with salmeterol, a long-acting beta-agonist that relaxes and widens the airways. Together, these components work synergistically to alleviate symptoms and improve lung function.

Advair is pivotal in reducing the frequency and severity of respiratory flare-ups and is prescribed in various strengths to cater to different severity levels of asthma and COPD. The convenient twice-daily dosing regimen ensures sustained symptom control and enhanced breathing capability.

However, it’s important to note that Advair is not suitable for addressing acute asthma attacks; instead, it is used for the ongoing management of symptoms. Common side effects include sore throat, headache, and respiratory infections. Patients are advised to rinse their mouths post-inhalation to prevent oral thrush, a common side effect.  

Uses of Advair 

• Asthma maintenance treatment
• COPD management

Benefits of Advair 

• Effectively manages asthma and COPD symptoms.
• It enhances airflow by reducing inflammation and widening airways.
• Lowers the frequency and severity of asthma attacks and COPD exacerbations.

Side Effects of Advair 

Common Advair side effects may include:

• Sore throat
• Nasal congestion
• Sinusitis
• White patches in the mouth and throat
• Hoarseness or changes in voice
• Headache
• Nausea and vomiting
• Back pain
• Muscle cramps
• Cough
• Bronchitis
• Dizziness
• Fever
• Rash or skin reactions
• Tremor or shakiness
• Increased heart rate (tachycardia)
• Nervousness or anxiety
• Insomnia or sleep disturbances
• Pharyngitis (inflammation of the pharynx)

[Note: This list is not exhaustive; if you notice any other symptoms not mentioned above, consult your doctor immediately.]

Advair Dosage

Forms & Strengths

Advair Diskus (dry powder inhaler):

• 100/50 mcg (100 mcg fluticasone propionate, 50 mcg salmeterol).
• 250/50 mcg (250 mcg fluticasone propionate, 50 mcg salmeterol).
• 500/50 mcg (500 mcg fluticasone propionate, 50 mcg salmeterol).

Advair HFA (metered-dose inhaler):

• 45/21 mcg (45 mcg fluticasone propionate, 21 mcg salmeterol).
• 115/21 mcg (115 mcg fluticasone propionate, 21 mcg salmeterol).
• 230/21 mcg (230 mcg fluticasone propionate, 21 mcg salmeterol).

Recommended Dosages

Asthma (Adults & adolescents 12 years and older):

• Advair Diskus: 100/50 mcg, 250/50 mcg, or 500/50 mcg twice daily.
• Advair HFA: 45/21 mcg, 115/21 mcg, or 230/21 mcg, two inhalations twice daily.

Asthma (Children 4-11 years):

• Advair Diskus: 100/50 mcg twice daily.

COPD (Adults):

• Advair Diskus: 250/50 mcg twice daily.

Elderly patients:

• No specific dosage adjustment is required.

Patients with hepatic impairment:

• Use with caution, and monitor for systemic corticosteroid effects.

Patients with renal impairment:

• No dosage adjustment is required.

How to Take Advair? 

• Shake the inhaler well before each use.
• Breathe out entirely, away from the inhaler.
• Place the mouthpiece between your lips and close them tightly around it.
• Inhale profoundly and steadily while pressing down on the canister.
• Hold your breath for close to 10 seconds, then exhale slowly.
• Rinse your mouth with water without swallowing after each use to prevent thrush.
• Clean the inhaler weekly with a dry cloth to avoid blockage.

Missed Dose 

If you miss a dose of Advair, take it as soon as you remember. However, if it’s almost time for your next dose of Advair, skip the missed dose and continue with your regular schedule. Do not take extra doses to make up for a missed one. 

[Note: Do not simultaneously take two doses of Advairto to compensate for a missed dose. This can spike your risk of experiencing side effects.]

Overdose

An overdose of Advair can lead to serious side effects like fast or irregular heartbeat, chest pain, tremors, seizures, and potentially life-threatening complications. Seek medical attention immediately if an overdose is suspected.

[Note: If you notice you have taken too much medication, call your local emergency number immediately.]

How Does Advair Work?

Advair combines two medications: fluticasone, a corticosteroid that lower inflammation in the airways & salmeterol, a long-acting beta-agonist that relaxes and opens the air passages in the lungs. Together, they help to prevent asthma attacks and manage chronic obstructive pulmonary disease (COPD) symptoms over time. This combination of medications is taken regularly to maintain airway function and reduce the frequency of respiratory symptoms.

Important Safety Precautions 

• Advair should not be used to treat sudden asthma attacks; have a rescue inhaler (e.g., albuterol) for emergencies.
• Inform your doctor about all medications you are taking, including prescription, over-the-counter, and herbal supplements.
• After using Advair, remember to rinse your mouth with water regularly to prevent thrush (yeast infection in the mouth).
• Ensure you do not exceed the prescribed dosage or frequency of Advair use.
• Monitor for signs of worsening asthma or COPD symptoms and inform your doctor promptly.
• Advair may increase the risk of pneumonia, especially in older adults; discuss with your doctor.
• Avoid exposure to infections like chickenpox or measles; inform your doctor if you are exposed.
• Inform healthcare providers of your use of Advair before any surgical procedures.
• Keep Advair away from heat or direct sunlight and store at room temperature.
• Do not use Advair if you are allergic to fluticasone or salmeterol.

Storage 

• Keep Advair at room temperature between 68°F to 77°F.
• Store Advair in a dry place away from moisture, heat, and direct sunlight.
• Store the inhaler in its sealed pouch until you’re ready to use it to protect it from moisture.
• Avoid puncturing the canister or exposing it to high heat or open flame.
• Keep Advair out of reach of children and pets.
• Do not store Advair in the bathroom due to moisture.

Advair Interactions 

• Ritonavir and other potent CYP3A4 inhibitors:
  • It can increase systemic exposure to fluticasone (a component of Advair).
  • This may lead to an increased risk of systemic corticosteroid side effects.
  • Concomitant use is not recommended.
• Beta-blockers: This may reduce the effectiveness of Advair.
• Diuretics: This may increase the risk of ECG changes or hypokalemia.
• Monoamine Oxidase Inhibitors (MAOIs) and Tricyclic Antidepressants (TCAs): May potentiate the cardiovascular effects of salmeterol (a component of Advair).
• Other long-acting beta2-agonists: Should not be used in combination with Advair due to the risk of overdose.
• Xanthine derivatives, steroids, or diuretics: May potentiate hypokalemia.
• Strong CYP3A4 inducers (e.g., rifampin): May decrease the systemic effects of inhaled corticosteroids.

[Note: This list of interactions isn’t complete. Talk to your doctor if you notice any interaction with food, over-the-counter drugs, prescriptions, or supplements.]

Advair Alternatives

• Symbicort (budesonide/formoterol)
• Breo Ellipta (fluticasone furoate/vilanterol)
• Dulera (mometasone/formoterol)
• AirDuo RespiClick (fluticasone propionate/salmeterol)
• Flovent (fluticasone)
• Pulmicort (budesonide)
• Qvar (beclomethasone)
• Asmanex (mometasone)
• Serevent (salmeterol)
• Foradil (formoterol)
• Spiriva (tiotropium)
• Incruse Ellipta (umeclidinium)
• Singulair (montelukast)
• Accolate (zafirlukast)
• Xolair (omalizumab)
• Nucala (mepolizumab)
• Fasenra (benralizumab)
• Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol)

[Note: Your healthcare provider will choose which Advair alternative is best for you. Taking or consuming them by yourself may cause serious side effects.] 

Frequently Asked Questions

Is Advair a steroid?

Yes, Advair contains fluticasone, a corticosteroid. Alongside fluticasone, it includes salmeterol, a long-acting beta agonist. These components work synergistically to gradually improve respiratory function.

How long does Advair stay in your system?

After taking a dose of Advair, it typically takes nearly 2 days for most of the medication to be eliminated. This estimation is based on the medication’s half-life. For optimal symptom control, Advair should be taken twice daily, approximately 12 hours apart.

How long does it take for Advair to work?

Initially, you may experience improved breathing within about 30 minutes after using Advair. However, it typically takes around 1 week or longer to achieve the maximum benefit from the medication. If you do not notice a significant changes in your symptoms after 2 weeks, your healthcare specialist may adjust your dosage or consider alternative treatments.

Is Advair safe for long-term use?

Advair is designed for regular use to manage symptoms of asthma or COPD, and many individuals use it long-term without significant issues. Concerns about long-term steroid use often relate to oral steroids, which can lead to bone weakening and higher blood sugar levels. Inhaled steroids like fluticasone, however, typically pose fewer risks of these side effects. If you have questions about the safety of using Advair over the long term, it’s essential to discuss them with your healthcare provider.

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